Calcium is not required for Immulectin-2 binding, but protects the protein from proteinase digestion

Insect Biochemistry and Molecular Biology

Volumn 36, Issue 6, 2006, Pages 505-516

  Yu, Xiao Qiang ^a   Ma, Yukun ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

C type lectin; Calcium independent; Carbohydrate recognition domain; Immulectin 2; Lipopolysaccharide; Lipoteichoic acid; Manduca Sexta

Indexed keywords

CALCIUM; IMMULECTIN 2 PROTEIN, MANDUCA SEXTA; IMMULECTIN-2 PROTEIN, MANDUCA SEXTA; INSECT PROTEIN; LECTIN; LIPID A; TRYPSIN;

ANIMAL; ANTIGEN ANTIBODY REACTION; ARTICLE; CHEMISTRY; DRUG EFFECT; IMMUNOLOGY; INNATE IMMUNITY; LEPIDOPTERA; METABOLISM; PROTEIN BINDING;

AGGLUTINATION; ANIMALS; CALCIUM; IMMUNITY, NATURAL; INSECT PROTEINS; LECTINS, C-TYPE; LIPID A; MANDUCA; PROTEIN BINDING; TRYPSIN;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA; MANDUCA SEXTA;

EID: 33646758172     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ibmb.2006.03.010     Document Type: Article

References (46)

1. Barkhausen T., Krettek C., and van Griensven M. L-selectin: adhesion, signaling and its importance in pathologic posttraumatic endotoxemia and non-septic inflammation. Exp. Toxicol. Pathol. 57 (2005) 39-52
2. Christophides G.K., Zdobnov E., Barillas-Mury C., Birney E., Blandin S., Blass C., Brey P.T., Collins F.H., Danielli A., Dimopoulos G., Hetru C., Hoa N.T., Hoffmann J.A., Kanzok S.M., Letunic I., Levashina E.A., Loukeris T.G., Lycett G., Meister S., Michel K., Moita L.F., Muller H.M., Osta M.A., Paskewitz S.M., Reichhart J.M., Rzhetsky A., Troxler L., Vernick K.D., Vlachou D., Volz J., von M.C., Xu J., Zheng L., Bork P., and Kafatos F.C. Immunity-related genes and gene families in Anopheles gambiae. Science 298 (2002) 159-165
3. Dodd R.B., and Drickamer K. Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity. Glycobiology 11 (2001) 71R-79R
4. Drickamer K. Evolution of Ca(2+)-dependent animal lectins. Prog. Nucleic Acid Res. Mol. Biol. 45 (1993) 207-232
5. Drickamer K., and Dodd R.B. C-Type lectin-like domains in Caenorhabditis elegans: predictions from the complete genome sequence. Glycobiology 9 (1999) 1357-1369
6. Drickamer K., and Fadden A.J. Genomic analysis of C-type lectins. Biochem. Soc. Symp. 69 (2002) 59-72
7. Dunn P.E., and Drake D. Fate of bacteria injected into naïve and immunized larvae of the tobacco hornworm, Manduca sexta. J. Invertebr. Pathol. 41 (1983) 77-85
8. East L., and Isacke C.M. The mannose receptor family. Biochim. Biophys. Acta. 1572 (2002) 364-386
9. Erbe D.V., Wolitzky B.A., Presta L.G., Norton C.R., Ramos R.J., Burns D.K., Rumberger J.M., Rao B.N., Foxall C., Brandley B.K., et al. Identification of an E-selectin region critical for carbohydrate recognition and cell adhesion. J. Cell Biol. 119 (1992) 215-227
10. Erbe D.V., Watson S.R., Presta L.G., Wolitzky B.A., Foxall C., Brandley B.K., and Lasky L.A. P- and E-selectin use common sites for carbohydrate ligand recognition and cell adhesion. J. Cell Biol. 120 (1993) 1227-1235
11. Feinberg H., Park-Snyder S., Kolatkar A.R., Heise C.T., Taylor M.E., and Weis W.I. Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor. J. Biol. Chem. 275 (2000) 21539-21548
12. Graves B.J., Crowther R.L., Chandran C., Rumberger J.M., Li S., Huang K.S., Presky D.H., Familletti P.C., Wolitzky B.A., and Burns D.K. Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains. Nature 367 (1994) 532-538
13. Hitchen P.G., Mullin N.P., and Taylor M.E. Orientation of sugars bound to the principal C-type carbohydrate-recognition domain of the macrophage mannose receptor. Biochem. J. 333 Pt 3 (1998) 601-608
14. Holmskov U., Thiel S., and Jensenius J.C. Collections and ficolins: humoral lectins of the innate immune defense. Annu. Rev. Immunol. 21 (2003) 547-578
15. Iobst S.T., Wormald M.R., Weis W.I., Dwek R.A., and Drickamer K. Binding of sugar ligands to Ca(2+)-dependent animal lectins. I. Analysis of mannose binding by site-directed mutagenesis and NMR. J. Biol. Chem. 269 (1994) 15505-15511
16. Jack D.L., and Turner M.W. Anti-microbial activities of mannose-binding lectin. Biochem. Soc. Trans. 31 (2003) 753-757
17. Koizumi N., Imamura M., Kadotani T., Yaoi K., Iwahana H., and Sato R. The lipopolysaccharide-binding protein participating in hemocyte nodule formation in the silkworm Bombyx mori is a novel member of the C-type lectin superfamily with two different tandem carbohydrate-recognition domains. FEBS Lett. 443 (1999) 139-143
18. Koizumi N., Imai Y., Morozumi A., Imamura M., Kadotani T., Yaoi K., Iwahana H., and Sato R. Lipopolysaccharide-binding protein of Bombyx mori participates in a hemocyte-mediated defense reaction against gram-negative bacteria. J. Insect Physiol. 45 (1999) 853-859
19. Laemmli M.K. Cleavage of structural proteins during the assembly of the head of bacteria-phage T4. Nature (Lond.) 227 (1970) 680-685
20. Ley K. Functions of selectins. Results Probl. Cell Differ. 33 (2001) 177-200
21. Ling E., and Yu X.-Q. Cellular encapsulation and melanization are enhanced by immulectins, pattern recognition receptors from the tobacco hornworm Manduca sexta. Dev. Com. Immunol. 33 (2006) 289-299
22. Ling E., and Yu X.-Q. Hemocytes from the tobacco hornworm Manduca sexta have distinct functions in phagocytosis of foreign particles and self dead cells. Dev. Comp. Immunol. 33 (2006) 301-309
23. Ma C., and Kanost M.R. A beta1,3-glucan recognition protein from an insect, Manduca sexta, agglutinates microorganisms and activates the phenoloxidase cascade. J. Biol. Chem. 275 (2000) 7505-7514
24. 2+ and monosaccharide binding to a C-type carbohydrate-recognition domain of the macrophage mannose receptor. J. Biol. Chem. 272 (1997) 5668-5681
25. Napper C.E., Dyson M.H., and Taylor M.E. An extended conformation of the macrophage mannose receptor. J. Biol. Chem. 276 (2001) 14759-14766
26. Ng K.K., Drickamer K., and Weis W.I. Structural analysis of monosaccharide recognition by rat liver mannose-binding protein. J. Biol. Chem. 271 (1996) 663-674
27. Patel K.D., Cuvelier S.L., and Wiehler S. Selectins: critical mediators of leukocyte recruitment. Semin. Immunol. 14 (2002) 73-81
28. Raetz C.R., and Whitfield C. Lipopolysaccharide endotoxins. Annu. Rev. Biochem. 71 (2002) 635-700
29. Shin S.W., Park S.S., Park D.S., Kim M.G., Kim S.C., Brey P.T., and Park H.Y. Isolation and characterization of immune-related genes from the fall webworm, Hyphantria cunea, using PCR-based differential display and subtractive cloning. Insect Biochem. Mol. Biol. 28 (1998) 827-837
30. Shin S.W., Park D.S., Kim S.C., and Park H.Y. Two carbohydrate recognition domains of Hyphantria cunea lectin bind to bacterial lipopolysaccharides through O-specific chain. FEBS Lett 467 (2000) 70-74
31. Taylor M.E., and Drickamer K. Structural requirements for high affinity binding of complex ligands by the macrophage mannose receptor. J. Biol. Chem. 268 (1993) 399-404
32. Taylor M.E., Bezouska K., and Drickamer K. Contribution to ligand binding by multiple carbohydrate-recognition domains in the macrophage mannose receptor. J. Biol. Chem. 267 (1992) 1719-1726
33. Torgersen D., Mullin N.P., and Drickamer K. Mechanism of ligand binding to E- and P-selectin analyzed using selectin/mannose-binding protein chimeras. J. Biol. Chem. 273 (1998) 6254-6261
34. Vasta G.R., Quesenberry M., Ahmed H., and O'Leary N. C-type lectins and galectins mediate innate and adaptive immune functions: their roles in the complement activation pathway. Dev. Comp. Immunol. 23 (1999) 401-420
35. Weis W.I., Kahn R., Fourme R., Drickamer K., and Hendrickson W.A. Structure of the calcium-dependent lectin domain from a rat mannose-binding protein determined by MAD phasing. Science 254 (1991) 1608-1615
36. Weis W.I., Drickamer K., and Hendrickson W.A. Structure of a C-type mannose-binding protein complexed with an oligosaccharide. Nature 360 (1992) 127-134
37. Weis W.I., Taylor M.E., and Drickamer K. The C-type lectin superfamily in the immune system. Immunol. Rev. 163 (1998) 19-34
38. Yu X.-Q., and Kanost M.R. Immulectin-2, a lipopolysaccharide-specific lectin from an insect, Manduca sexta, is induced in response to Gram-negative bacteria. J. Biol. Chem. 275 (2000) 37373-37381
39. Yu X.-Q., and Kanost M.R. Binding of hemolin to microbial lipopolysaccharide and lipoteichoic acid: an immunoglobulin superfamily member from insects as a pattern recognition receptor. Eur. J. Biochem. 269 (2002) 1827-1834
40. Yu X.-Q., and Kanost M.R. Manduca sexta lipopolysaccharide-specific immulectin-2 protects larvae from bacterial infection. Dev. Com. Immunol. 27 (2003) 189-196
41. Yu X.-Q., and Kanost M.R. Immulectin-2, a pattern recognition receptor that stimulates hemocyte encapsulation and melanization in the tobacco hornworm, Manduca sexta. Dev. Com. Immunol. 28 (2004) 891-900
42. Yu X.-Q., Gan H., and Kanost M.R. Immulectin, an inducible C-type lectin from an insect, Manduca sexta, stimulates activation of plasma prophenol oxidase. Insect Biochem. Mol. Biol. 29 (1999) 585-597
43. Yu X.-Q., Tracy M.E., Ling E., Scholz F.R., and Trenczek T. A novel C-type immulectin-3 from Manduca sexta is translocated from hemolymph into the cytoplasm of hemocytes. Insect Biochem. Mol. Biol. 35 (2005) 285-295
44. Yu X.-Q., Ling E., Tracy M.E., and Zhu Y. Immulectin-4 from the tobacco hornworm Manduca sexta binds to lipopolysaccharide and lipoteichoic acid. Insect Mol. Biol. 15 (2006) 119-128
45. Zamze S., Martinez-Pomares L., Jones H., Taylor P.R., Stillion R.J., Gordon S., and Wong S.Y. Recognition of bacterial capsular polysaccharides and lipopolysaccharides by the macrophage mannose receptor. J. Biol. Chem. 277 (2002) 41613-41623
46. Zelensky A.N., and Gready J.E. C-type lectin-like domains in Fugu rubripes. BMC Genomics 5 (2004) 51