In vitro and in vivo prodrug therapy of prostate cancer using anti-γ-Sm-scFv/hCPA fusion protein

Prostate

Volumn 66, Issue 8, 2006, Pages 858-866

  Hao, Xiao Ke ^a   Liu, Jia Yun ^a   Yue, Qiao Hong ^a   Wu, Guo Jun ^a   Bai, Yu Jie ^b   Yin, Ying ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

ADEPT; Carboxypeptidase A(CPA); Methotrexate (MTX); Prostate cancer; scFv

Indexed keywords

CARBOXYPEPTIDASE A; HYBRID PROTEIN; IODINE 125; METHOTREXATE; SEMINOPROTEIN ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DIRECTED ENZYME PRODRUG THERAPY; ARTICLE; CANCER INHIBITION; CELL CYCLE; COLONY FORMATION; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; CYTOTOXICITY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROSTATE CANCER; RADIOISOTOPE DISTRIBUTION; SURVIVAL TIME; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES, NEOPLASM; CARBOXYPEPTIDASES A; CELL CYCLE; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; MALE; METHOTREXATE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; PHENYLALANINE; PRODRUGS; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RECOMBINANT FUSION PROTEINS; TRANSPLANTATION, HETEROLOGOUS; TUMOR STEM CELLS;

EID: 33646750584     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.20402     Document Type: Article

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