Induction of apoptosis in leukemia cell lines by Linum persicum and Euphorbia cheiradenia

Journal of Cancer Research and Clinical Oncology

Volumn 132, Issue 7, 2006, Pages 427-432

  Amirghofran, Zahra ^a,b   Bahmani, Masoud ^a   Azadmehr, Abbas ^a   Javidnia, Katayoun ^b  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Apoptosis; Euphorbia cheiradenia; Linum persicum

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; DNA FRAGMENT; EUPHORBIA CHEIRADENIA EXTRACT; EUPHORBIA EXTRACT; LINUM PERSICUM EXTRACT; PLANT EXTRACT; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ANGIOSPERM; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; COLORIMETRY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; EUPHORBIA; EUPHORBIA CHEIRADENIA; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; IRAN; LEUKEMIA CELL; LINUM PERSICUM; MEDICINAL PLANT; PRIORITY JOURNAL;

ANTICARCINOGENIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; COLORIMETRY; COLORING AGENTS; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EUPHORBIA; FLAX; FLOW CYTOMETRY; HELA CELLS; HUMANS; JURKAT CELLS; K562 CELLS; LEUKEMIA; PHYTOTHERAPY; PLANT EXTRACTS; TETRAZOLIUM SALTS; THIAZOLES;

EID: 33646719952     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-006-0084-x     Document Type: Article

References (25)

1. Adam-Klages S, Adam D, Janssen O, Kabelitz D (2005) Death receptors and caspases: role in lymphocyte proliferation, cell death, and autoimmunity. Immunol Res 33:149-166
2. Canel C, Moraes RM, Dayan FE, Ferreira D (2000) Podophyllotoxin. Phytochemistry 54:115-120
3. Corea G, Fattorusso E, Lanzotti V, Taglialatela-Scafati O, Appendino G, Ballero M, Simon PN, Dumontet C, Di Pietro A (2003) Modified jatrophane diterpenes as modulators of multidrug resistance from Euphorbia dendroides L. Bioorg Med Chem 11:5221-5227
4. Cuendet M, Pezzuto JM (2004) Antitumor activity of bruceantin: an old drug with new promise. J Nat Prod 67:269-272
5. Gillespie SK, Zhang XD, Hersey P (2004) Ingenol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells. Mol Cancer Ther 3:1651-1658
6. Herrmann M, Lorenz HM, Voll R, Grunke M, Woith W, Kalden JR (1994) A rapid and simple method for the isolation of apoptotic DNA fragments. Nucleic Acids Res 22:5506-5507
7. Heywood VH (1979) Flowering plants of the world. Oxford University Press, Oxford, pp 207-208
8. Hohmann J, Molnar J, Redei D, Evanics F, Forgo P, Kalman A, Argay G, Szabo P (2002) Discovery and biological evaluation of a new family of potent modulators of multidrug resistance: reversal of multidrug resistance of mouse lymphoma cells by new natural jatrophane diterpenoids isolated from Euphorbia species. J Med Chem 45:2425-2431
9. Kartal M, Konuklugil B, Indrayanto G, Alfermann AW (2004) Comparison of different extraction methods for the determination of podophyllotoxin and 6-methoxypodophyllotoxin in Linum species. J Pharm Biomed Anal 35:441-447
10. Kupchan SM, Uchida I, Branfman AR, Dailey RG Jr, Fei BY (1976) Antileukemic principles isolated from Euphorbiaceae plants. Science 191:571-572
11. Li X, Ji L, Wang Z (2002) Advances in the study on the effects of Chinese herbal drugs on apoptosis. Zhong Yao Cai 25:135-139
12. Liu LG, Tan RX (2001) New jatrophane diterpenoid esters from Euphorbia turczaninowii. J Nat Prod 64:1064-1068
13. Liu WK, Ho JC, Qin G, Che CT (2002) Jolkinolide B induces neuroendocrine differentiation of human prostate LNCaP cancer cell line. Biochem Pharmacol 63:951-957
14. Ogbourne SM, Suhrbier A, Jones B, Cozzi SJ, Boyle GM, Morris M, McAlpine D, Johns J, Scott TM, Sutherland KP, Gardner JM, Le TT, Lenarczyk A, Aylward JH, Parsons PG (2004) Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death. Cancer Res 64:2833-2839
15. Petersen M, Alfermann AW (2001) The production of cytotoxic lignans by plant cell cultures. Appl Microbiol Biotechnol 55:135-142
16. Ravikanth V, Lakshmi Niranjan Reddy V, Vijender Reddy A, Ravinder K, Prabhakar Rao T, Siva Ram T, Anand Kumar K, Prakesh Vamanarao D, Venkateswarlu Y (2003) Three new ingol diterpenes from Euphorbia nivulia: evaluation of cytotoxic activity. Chem Pharm Bull (Tokyo) 51:431-434
17. Rechinger KH (1982) Euphorbiaceae. In: Rechinger KH (ed) Flora iranica, no.6. Akademische Druck-u, Verlagsanstalt, Graz, pp 8-48
18. Thomson M, Ali M (2003) Garlic [Allium sativum]: a review of its potential use as an anti-cancer agent. Curr Cancer Drug Targets 3:67-81
19. Tsan MF, White JE, Maheshwari JG, Chikkappa G (2002) Antileukemia effect of resveratrol. Leuk Lymphoma 43:983-987
20. Valente C, Pedro M, Duarte A, Nascimento MS, Abreu PM, Ferreira MJ (2004) Bioactive diterpenoids, a new jatrophane and two ent-abietanes, and other constituents from Euphorbia pubescens. J Nat Prod 67:902-904
21. Van Uden W, Homan B, Woerdenbag HJ, Pras N, Malingre TM, Wichers HJ, Harkes M (1992) Isolation, purification, and cytotoxicity of 5-methoxypodophyllotoxin, a lignan from a root culture of Linum flavum. J Nat Prod 55:102-110
22. Vasilev NP, Ionkova I (2005) Cytotoxic activity of extracts from Linum cell cultures. Fitoterapia 76:50-53
23. Vasilev N, Momekov G, Zaharieva M, Konstantinov S, Bremner P, Heinrich M, Ionkova I (2005) Cytotoxic activity of a podophyllotoxin-like lignan from Linum tauricum Willd. Neoplasma 52:425-429
24. Weiss SG, Tin-Wa M, Perdue RE, Farnsworth NR (1975) Potential anticancer agents II: antitumor and cytotoxic lignans from Linum album (Linaceae). J Pharm Sci 64:95-98
25. Wu TS, Lin YM, Haruna M, Pan DJ, Shingu T, Chen YP, Hsu HY, Nakano T, Lee KH (1991) Antitumor agents, 119. Kansuiphorins A and B, two novel antileukemic diterpene esters from Euphorbia kansui. J Nat Prod 54:823-829