Tamm-Horsfall protein knockout mice do not develop medullary cystic kidney disease [2]

Kidney International

Volumn 69, Issue 10, 2006, Pages 1914-1915

  Raffi, H ^a   Bates Jr , J M ^a   Laszik, Z ^a   Kumar, S ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TAMM HORSFALL GLYCOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AUTOSOMAL DOMINANT DISORDER; BODY WEIGHT; CLINICAL FEATURE; CONTROLLED STUDY; FEEDING BEHAVIOR; FEMALE; GENE MUTATION; GOUT; HISTOPATHOLOGY; HOMOLOGOUS RECOMBINATION; INFLAMMATORY INFILTRATE; KIDNEY BIOPSY; KIDNEY FAILURE; KIDNEY FIBROSIS; KNOCKOUT MOUSE; LETTER; MALE; MEDULLARY SPONGE KIDNEY; MOUSE; NONHUMAN; PHYSICAL ACTIVITY; POLYURIA; PRIORITY JOURNAL; URIC ACID NEPHROPATHY;

ANIMALS; MICE; MICE, KNOCKOUT; MUCOPROTEINS; POLYCYSTIC KIDNEY DISEASES; RECOMBINATION, GENETIC; STAINING AND LABELING;

EID: 33646704233     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5000411     Document Type: Letter

References (4)

1. Rezende-Lima W, Parreira KS, Garcia-Gonzalez M et al. Homozygosity for uromodulin disorders: FJHN and MCKD-type 2. Kidney Int 2004; 66: 558-563.
2. Hart TC, Gorry MC, Hart PS et al. Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy. J Med Genet 2002; 39: 882-892.
3. Bleyer AJ, Hart TC, Shihabi Z et al. Mutations in the uromodulin gene decrease urinary excretion of Tamm-Horsfall protein. Kidney Int 2004; 66: 974-977.
4. Bates JM, Raffi HM, Prasadan K et al. Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int 2004; 65: 791-797.