The reduction of cholesteryl linoleate in lipoproteins: An index of clinical severity in β-thalassemia/Hb E

Clinical Chemistry and Laboratory Medicine

Volumn 44, Issue 5, 2006, Pages 574-581

  Luechapudiporn, Rataya ^a   Morales, Noppawan Phumala ^b   Fucharoen, Suthat ^c   Chantharaksri, Udom ^b  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Cholesteryl linoleate; Hypocholesterolemia; Non transferrin bound iron; Oxidative stress; Thalassemia

Indexed keywords

BIOLOGICAL MARKER; CHOLESTEROL OLEATE; HEMOGLOBIN E; HIGH DENSITY LIPOPROTEIN; LINOLEIC ACID; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSFERRIN;

ARTICLE; ATHEROGENESIS; BETA THALASSEMIA; CORRELATION ANALYSIS; DISEASE SEVERITY; GENETIC RISK; HIGH RISK PATIENT; HUMAN; HUMAN CELL; IRON OVERLOAD; LIPID PEROXIDATION; LIPOPROTEIN METABOLISM; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN MODIFICATION;

ADOLESCENT; ADULT; ALPHA-TOCOPHEROL; BETA-THALASSEMIA; CASE-CONTROL STUDIES; CHEMISTRY, CLINICAL; CHILD; CHOLESTEROL ESTERS; FEMALE; HEMOGLOBIN E; HUMANS; LIPID PEROXIDATION; LIPOPROTEINS; MALE; MIDDLE AGED; OXIDATIVE STRESS; OXYGEN;

EID: 33646692249     PISSN: 14346621     EISSN: 14346621     Source Type: Journal    
DOI: 10.1515/CCLM.2006.093     Document Type: Article

References (40)

1. Livrea MA, Tesoriere L, Pintaudi AM, Calabrese A, Maggio A, Freisleben HJ, et al. Oxidative stress and antioxidant status in b-thalassemia major: iron overload and depletion of lipid soluble antioxidants. Blood 1996;88:3608-14.
2. Sonakul D, Fucharoen S. Pulmonary thromboembolism in thalassemic patients. South East Asian J Trop Med Pubic Health 1992;23:25-8.
3. Sonakul D, Pacharee P, Laohapand T, Fucharoen S. Pulmonary artery obstruction in thalassemia. South East Asian J Trop Med Pubic Health 1980;11:516-23.
4. Wong V, Yu Y, Laing R, Tso W, Li A, Chan TK. Cerebral thrombosis in β-thalassemia/hemoglobin E disease. Stroke 1990;21:812-6.
5. Pascher F, Keen R. Ulcers of the leg in Cooley's anemia. N Engl J Med 1957;256:1220-2.
6. Steinberg D, Parthasaraty S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol. Modifications of low density lipoprotein that increase its atherogenicity. N Engl J Med 1989;320:915-24.
7. Berliner JA, Heinecke JW. The role of oxidized lipoproteins in atherogenesis. Free Radic Biol Med 1996;20:707-27.
8. Goldfarb AW, Rachmilewitz EA, Eisenberg S. Abnormal low and high density lipoproteins in homozygous beta-thalassaemia. Br J Haematol 1991;79:481-6.
9. Livrea MA, Tesoriere L, Maggio A, D'Arpa D, Pintaudi AM, Pedone E. Oxidative modification of low-density lipoprotein and atherogenetic risk in beta-thalassemia. Blood 1998;92:3936-42.
10. Giardini O, Murgis F, Martino F, Mannarino O, Corrado G. Serum lipid pattern in beta-thalassemia. Acta Haematol 1978;60:100-7.
11. Maioli M, Cuccuru GB, Pranzetti P, Pacifico A, Cherchi GM. Plasma lipids and lipoproteins pattern in beta-thalassemia major. Acta Haematol 1984;71:106-10.
12. Maioli M, Vigna GB, Tonolo G, Brizzi P, Ciccarese M, Donega P, et al. Plasma lipoprotein composition, apolipoprotein(a) concentration and isoforms in beta-thalassemia. Atherosclerosis 1997;131:127-33.
13. Tesoriere L, D'Arpa D, Maggio A, Giaccone V, Pedone E, Livrea MA. Oxidation resistance of LDL is correlated with vitamin E status in β-thalassemia intermedia. Atherosclerosis 1998;137:429-35.
14. Altamentova SM, Marva E, Shaklai N. Oxidative interaction of unpaired hemoglobin chains with lipids and proteins: a key for modified serum lipoproteins in thalassemia. Arch Biochem Biophys 1997;345:39-46.
15. Steinberg D. Oxidative modification of LDL and atherogenesis. Circulation 1997;95:1062-71.
16. Chisolm G, Ma G, Irwin K, Martin L, Gunderson K, Linberg L, et al. 7β-hydroperoxycholest-5-en-3β-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized low density lipoprotein. Proc Natl Acad Sci USA 1994;91:11452-6.
17. Brook CJ, Harland WA, Steel G. Lipids of human atheroma: isolation of hydroxyoctadecadienoic acids from advanced aortal lesions. Biochim Biophys Acta 1970;202:563-6.
18. Belkner J, Stender H, Kuhn H. The rabbit 15-lipoxygenase preferentially oxygenates LDL cholesterol esters, and this reaction does not require vitamin E. J Biol Chem 1998;273:23225-32.
19. Winichagoon P, Fucharoen S, Chen P, Wasi P. Genetic factors affecting clinical severity in β-thalassemia syndromes. J Pediatr Hematol Oncol 2000;22:573-80.
20. Havel RJ, Eder HA, Bragdon JH. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 1955;34:1345-53.
21. Frei B, Yamamoto Y, Niclas D, Ames BN. Evaluation of an isoluminal chemiluminescence assay for the detection of hydroperoxides in human blood plasma. Anal Biochem 1988;175:120-30.
22. Kritharides L, Jessup W, Gifford J, Dean RT. A method for defining the stages of low-density lipoprotein oxidation by the separation of cholesterol- and cholesteryl ester-oxidation products using HPLC. Anal Biochem 1993;213:79-89.
23. Al-Refaie FN, Wickena DG, Wonke B, Kontoghiorghens G, Hoffbrand A. Serum non-transferrin-bound iron in beta-thalassemia major patients treated with desferrioxamine and L1. Br J Haematol 1992;82:431-6.
24. Asakawa T, Matsushita S. Coloring condition of thiobarbituric acid test for detecting lipid hydroperoxide. Lipids 1980;15:137-40.
25. Uchiyama M, Mihara M. Determination of malondialdehyde precursor in tissue by thiobarbituric acid test. Anal Biochem 1978;86:271-8.
26. Zaspel BJ. Determination of alpha-tocopherol in tissues and plasma by high performance liquid chromatography. Ann Biochem 1983;130:146-50.
27. Kuhn H, Belkner J, Wiesner R, Schewe T, Lankin VZ, Tikhaze AK. Structure elucidation of oxygenated lipids in human atherosclerotic lesions. Eicosanoids 1992;5:17-22.
28. Lenz M, Hughes H, Mitchell J, Via D, Guyton J, Taylor A, et al. Lipid hydroperoxy and hydroxy derivatives in copper-catalyzed oxidation of low density lipoprotein. J Lipid Res 1990;31:1043-50.
29. Han J, Hajjar DP, Tauras JM, Nicholson AC. Cellular cholesterol regulates expression of the macrophage type B scavenger receptor, CD 36. J Lipid Res 1999;40:830-8.
30. Leitinger N. Cholesteryl ester oxidation products in atherosclerosis. Mol Aspects Med 2003;24:239-50.
31. 2 is used as oxidant. Biochim Biophys Acta 1998;1392:23-40.
32. Hersberger M, von Eckardstein A. Low high-density lipoprotein cholesterol. Drugs 2003;63:1907-45.
33. Bowry VW, Stanley KK, Stocker R. High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors. Proc Natl Acad Sci USA 1992;89:10316-20.
34. Durrington PN, Mackness B, Mackness MI. Paraoxonase and atherosclerosis. Arterioscler Thromb Vasc Biol 2001;21:473-80.
35. Gowri MS, Van der Westhuyzen DR, Bridges SR, Anderson JW. Decreased protection by HDL from poorly controlled type 2 diabetic subjects against LDL oxidation may be due to the abnormal composition of HDL. Arterioscler Thromb Vasc Biol 1999;19:2226-33.
36. Carpenter KL, Taylor SE, Veen C, Williamson BK, Ballantine JA, Mitchinson MJ. Lipids and oxidised lipids in human atherosclerotic lesions at different stages of development. Biochim Biophys Acta 1995;1256:141-50.
37. Shinar E, Rachmilewitz EA. Oxidative denaturation of red blood cells in thalassemia. Sem Hematol 1990;27:70-82.
38. Jarolim P, Lahav M, Liu S, Palek J. Effect of hemoglobin oxidation products on the stability of red cell membrane skeletons and the associations of skeletal proteins: correlation with a release of hemin. Blood 1990;76:2125-31.
39. Phumala N, Porasuphatana S, Unchern S, Pootrakul P, Fucharoen S, Chantharaksri U. Hemin: a possible cause of oxidative stress in blood circulation of β-thalassemia/hemoglobin E Disease. Free Radic Res 2003;37:129-35.
40. Tribble DL, Chu BM, Levine GA, Krauss RM, Gong EL. Selective resistance of LDL core lipids to iron-mediated oxidation: implications for the biological properties of iron-oxidized LDL. Arterioscler Thromb Vasc Biol 1996;16:1580-7.