Biphasic insulin aspart vs. human insulin in adolescents with type 1 diabetes on multiple daily insulin injections

Pediatric Diabetes

Volumn 7, Issue 1, 2006, Pages 4-10

  Mortensen, Henrik ^a   Kocova, Mirjana ^b   Teng, Lot Yin ^c   Keiding, Jens ^d   Bruckner, Iona ^e   Philotheou, Areti ^f  

^a International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^b Pediatric Clinic   (Macedonia)

^c Novo Nordisk Pharma Singapore Pte Ltd   (Singapore)

^d NOVO NORDISK A S   (Denmark)

^e N Malaxa Hospital   (Romania)

^f UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Adolescents; Biphasic insulin aspart; Body mass index; Prandial blood glucose; Type 1 diabetes

Indexed keywords

BIASP; BIPHASIC INSULIN; GLUCOSE; HEMOGLOBIN A1C; HUMAN INSULIN; INSULIN ASPART; INSULIN LISPRO; ISOPHANE INSULIN;

ADOLESCENT; ARTICLE; BODY MASS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG SAFETY; FEMALE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; HYPOGLYCEMIA; INCIDENCE; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MULTIPLE DRUG DOSE; PARALLEL DESIGN; PATIENT MONITORING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; TREATMENT DURATION;

ADOLESCENT; BLOOD GLUCOSE; BODY MASS INDEX; CHILD; DIABETES MELLITUS, TYPE 1; DRUG ADMINISTRATION SCHEDULE; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; INJECTIONS, SUBCUTANEOUS; INSULIN; MALE;

EID: 33646689784     PISSN: 1399543X     EISSN: 13995448     Source Type: Journal    
DOI: 10.1111/j.1399-543X.2006.00138.x     Document Type: Article

References (18)

1. D iabetes C ontrol and C omplications T rial R esearch G roup. Adverse events and their association with treatment regimens in the diabetes control and complications trial. Diabetes Care 1995: 18: 1415-1427.
2. B ryden KS, P eveler RC, S tein A, N eil A, M ayou RA, D unger DB. Clinical and psychological course of diabetes from adolescence to young adulthood: A longitudinal cohort study. Diabetes Care 2001: 24: 1536-1540.
3. M ortensen HB, H ougaard P. Comparison of metabolic control in a cross-sectional study of 2,873 children and adolescents with IDDM from 18 countries. The Hvidore Study Group on Childhood Diabetes. Diabetes Care 1997: 20: 714-720.
4. FDA -C enter F or D rug E valuation and R esearch (CDER). Draft guidance: Evaluation of new treatments for diabetes mellitus, 1998.
5. M ortensen HB, R obertson KJ, A anstoot HJ et al. Insulin management and metabolic control of type 1 diabetes mellitus in childhood and adolescence in 18 countries. Hvidore Study Group on Childhood Diabetes. Diabet Med 1998: 15: 752-759.
6. T anner JM. Normal growth and techniques of growth assessments. Clin Endocrinol Metab 1986: 15: 411-451.
7. B runner GA, H irschberger S, S endlhofer G et al. Post-prandial administration of the insulin analogue insulin aspart in patients with type 1 diabetes mellitus. Diabet Med 2000: 17: 371-375.
8. W eyer C, H eise T, H einemann L. Insulin aspart in a 30/70 premixed formulation. Pharmacodynamic properties of a rapid-acting insulin analog in stable mixture. Diabetes Care 1997: 20: 1612-1614.
9. H ermansen K, V aaler S, M adsbad S et al. Postprandial glycemic control with biphasic insulin aspart in patients with type 1 diabetes. Metabolism 2002: 51: 896-900.
10. Swift PGF, ed. Consensus guidelines for the management of type 1 diabetes mellitus in children and alolescents. In: ISPAD Guidelines 2000. Zeist, Netherlands: Medforum, 2000.
11. C ole TJ, F reeman JV, P reece MA. Body mass index reference curves for the UK, 1990. Arch Dis Child 1995: 73: 23-29
12. D orchy H, R oggemans MP, W illems D. Glycated hemoglobin and related factors in diabetic children and adolescents under 18 years of age: A Belgian experience. Diabetes Care 1997: 20: 2-6.
13. H ermansen K, F ontaine P, K ukolja KK, P eterkova V, L eth G, G all MA. Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin) in basal-bolus therapy for patients with type 1 diabetes. Diabetologia 2004: 47: 622-629.
14. H oey H, A anstoot HJ, C hiarelli F et al. Good metabolic control is associated with better quality of life in 2,101 adolescents with type 1 diabetes. Diabetes Care 2001: 24: 1923-1928.
15. D anne T, K ordonouri O, E nders I, W eber B. Factors influencing height and weight development in children with diabetes. Results of the Berlin Retinopathy Study. Diabetes Care 1997: 20: 281-285.
16. B ryden KS, N eil A, M ayou RA, P eveler RC, F airburn CG, D unger DB. Eating habits, body weight, and insulin misuse. A longitudinal study of teenagers and young adults with type 1 diabetes. Diabetes Care 1999 22: 1956-1960.
17. D aneman D, O lmsted M, R ydall A, M aharaj S, R odin G. Eating disorders in young women with type 1 diabetes. Prevalence, problems and prevention. Horm Res 1998: 50 (Suppl. 1): 79-86.
18. WHO. Health and health behaviour among young people. Currie C, Hurrelmann K, Settertobulte W, Smith R, and Todd J. 1997/98 International Report. 2000. WHO Regional Office for Europe, Copenhagen. WHO Policy Series. Health Policy for Children and Adolescents, Issue 1.