Cytotoxic diterpenoids from Podocarpus madagascariensis from the Madagascar rainforest

Natural Product Research

Volumn 20, Issue 6, 2006, Pages 606-610

  Reynolds, Micah ^a   Chaturvedula, V S Prakash ^a   Ratovoson, Fidisoa ^b   Andriantsiferana, Rabodo ^c   Rasamison, Vincent E ^c   Guza, Rebecca C ^a   Kingston, David G I ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b MISSOURI BOTANICAL GARDEN   (United States)

^c Centre National d'Application des Recherches Pharmaceutiques   (Madagascar)

Author keywords

Cytotoxicity; Phenolic diterpenoids; Podocarpaceae; Podocarpus madagascariensis

Indexed keywords

19 HYDROXYTOTAROL; 4BETA CARBOXY 19 NORTOTAROL; DITERPENOID; METHYL 13 HYDROXY 14 ISOPROPYL 9(11),12,14(8) PODOCARATRIENE 19 OATE; PLANT EXTRACT; PODOCARPUS MADAGASCARIENSIS EXTRACT; TOTARADIOL; UNCLASSIFIED DRUG;

ARTICLE; BARK; CANCER CELL CULTURE; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CYTOTOXICITY; DRUG ACTIVITY; DRUG DETERMINATION; DRUG IDENTIFICATION; GYMNOSPERM; MADAGASCAR; METHYLATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OVARY CANCER; PLANT ROOT; PODOCARPUS MADAGASCARIENSIS; RAIN FOREST;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DITERPENES; ECOSYSTEM; FEMALE; GYMNOSPERMS; HUMANS; MADAGASCAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OVARIAN NEOPLASMS; PLANT BARK; PLANT ROOTS; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET;

GYMNOSPERMAE; PODOCARPACEAE; PODOCARPUS;

EID: 33646687261     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786410500249315     Document Type: Article

References (8)

1. Williams, RB and Norris, A and Merola, J and Miller, JS and Andriantsiferana, R and Rasamison, VE and Kingston, D.G.I. J. Nat. Prod. (in press)Biodiversity Conservation and Drug Discovery in Madagascar, Part 15. For Part 14, see
2. Cao, S and Schilling, SJK and Miller, JS and Andriantsiferana, R and Rasamison, VE and Kingston, D.G.I. (2004) J. Nat. Prod., 67, pp. 454.
3. Murphy, BT and Cao, S and Norris, A and Ratovoson, F and Andriantsiferana, R and Rasamison, VE and Kingston, D.G.I. (2005) J. Nat. Prod., 68, pp. 417.
4. Cambie, RC and Simpson, WRJ and Colebrook, LD. (1963) Tetrahedron, 19, pp. 209.
5. Cambie, RC and Cox, RE and Croft, KD and Sidwell, D. (1984) Phytochemistry, 23, pp. 333.
6. Cambie, RC and Cos, RE and Croft, KD and Sidwell, D. (1983) Phytochemistry, 22, pp. 1163.
7. Ying, B-P and Kubo, I. (1991) Phytochemistry, 30, pp. 1951.
8. Louie, KG and Behrens, BC and Kinsella, TJ and Hamilton, TC and Grotzinger, KR and McKoy, WM and Winker, MA and Ozols, RF. (1985) Cancer Res., 45, pp. 2110.