Albumin stimulation of eosinophil migration involves PI3-kinases and is associated with diminished eosinophil CD49d and CD49f expression

International Archives of Allergy and Immunology

Volumn 140, Issue 2, 2006, Pages 113-120

  Lampinen, Maria ^a   Håkansson, Lena Douhan ^a   Venge, Per ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Adhesion molecules; Albumin; Chemotaxis; Eosinophil; Migration; Signal transduction

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; ALBUMIN; ALPHA4 INTEGRIN; ALPHA6 INTEGRIN; CELL ADHESION MOLECULE; INTERLEUKIN 2; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE C INHIBITOR; WORTMANNIN;

ARTICLE; ASSAY; BOYDEN CHAMBER ASSAY; CELL ACTIVATION; CELL ADHESION; CELL SIZE; CELL SURFACE; CHEMOKINESIS; CHEMOTAXIS; EOSINOPHIL; FLOW CYTOMETRY; GRANULOCYTE; HUMAN; HUMAN CELL; LEUKOCYTE MIGRATION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; ANDROSTADIENES; CELL ADHESION; CELL SIZE; CHEMOTAXIS, LEUKOCYTE; CHROMONES; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; EOSINOPHILS; FLOW CYTOMETRY; HUMANS; INDOLES; INTEGRIN ALPHA4; INTEGRIN ALPHA6; INTERLEUKIN-2; MIDDLE AGED; MORPHOLINES; PROTEIN KINASE INHIBITORS; SERUM ALBUMIN; SIGNAL TRANSDUCTION;

EID: 33646585114     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000092412     Document Type: Article

References (28)

1. Venge P, Håkansson L: The eosinophil and asthma; in Kaliner M, Persson CGA, Barnes PJ, Debber M (eds): Asthma: Pathophysiology and Treatment. New York, Marcel Dekker, 1990, pp 477-502.
2. Lampinen M, Carlson M, Sangfelt P, Taha Y, Thörn M, Lööf L, Raab Y, Venge P: IL-5 and TNF-α participate in recruitment of eosinophils to intestinal mucosa in ulcerative colitis. Dig Dis Sci 2001;46:2004-2009.
3. Håkansson L, Carlson M, Stålenheim G, Venge P: Migratory responses of eosinophil and neutrophil granulocytes from patients with asthma. J Allergy Clin Immunol 1990;85:743-750.
4. Boyden S: The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. J Exp Med 1962;115:453-466.
5. Falk W, Goodwin RH Jr, Leonard EJ: A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration. J Immunol Methods 1980;33:239-247.
6. Wilkinson PC: A requirement for albumin as a carrier for low molecular weight leukocyte chemotactic factors. Exp Cell Res 1976;103:415-420.
7. 4 is dependent on chemokinetic factors. J Leukoc Biol 1985;38:521-530.
8. Valerius NH: Chemotaxis, spreading and oxidative metabolism of neutrophils: influence of albumin in vitro. Acta Pathol Microbiol Immunol Scand 1983;91:43-49.
9. Lynch OT, Giembycz MA, Barnes PJ, Hellewell PG, Lindsay MA: 'Outside-in' signalling mechanisms underlying CD11b/CD18-mediated NADPH oxidase activation in human adherent blood eosinophils. Br J Pharmacol 1999;128:1149-1158.
10. Amin RM, Hays JH, Shakir KM: Phosphoinositide turnover in human platelets is stimulated by albumin. Life Sci 1991;49:1707-1719.
11. Yoshikawa M, Matsumoto K, Iida M, Akasawa A, Moriyama H, Saito H: Effect of extracellular matrix proteins on platelet-activating factor-induced eosinophil chemotaxis. Int Arch All Immunol 2002;128:3-11.
12. Lampinen M, Håkansson L, Venge P: Interleukin-2 inhibits eosinophil migration but is counteracted by IL-5 priming. Clin Exp All 2001;31:249-258.
13. Hansel TT, De Vries IJM, Iff T, Rihs S, Wandzilak M, Betz S, Blaser K, Walker C: An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils. J Immunol Methods 1991;145:105-110.
14. Wilkinson PC: Principles of the measurement of leukocyte chemotaxis using Boyden's method; in Chemotaxis and Inflammation. London, Churchill Livingstone, 1974, pp 33-53.
15. Sabroe I, Hartnell A, Jopling LA, Bel S, Ponath PD, Pease JE, Collins PD, Williams TJ: Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways. J Immunol 1999;162:2946-2955.
16. Sotsios Y, Ward SG: Phosphoinositide 3-kinase: a key biochemical signal for cell migration in response to chemokines. Immunol Rev 2000;177:217-235.
17. Pinho V, Souza DG, Barsante MM, Hamer FP, De Freitas MS, Rossi AG, Teixeira MM: Phosphoinositide-3 kinases critically regulate the recruitment and survival of eosinophils in vivo: importance for the resolution of allergic inflammation. J Leukoc Biol 2005;77:800-810.
18. Palframan RT, Collins PD, Severs NJ, Rothery S, Williams TJ, Rankin SM: Mechanisms of acute eosinophil mobilization from the bone marrow stimulated by interleukin 5: the role of specific adhesion molecules and phosphatidylinositol 3-kinase. J Exp Med 1998;188:1621-1632.
19. Woschnagg C, Garcia RC, Venge P: The mechanisms of serum-treated zymosan (STZ)-induced oxidative metabolism by human eosinophils and the effects of IL-5 priming. Allergy 2001;56:639-645.
20. Sano M, Leff AR, Myou S, Boetticher E, Meliton AY, Learoyd J, Lambertino AT, Munoz NM, Zhu X: Regulation of interleukin-5-induced beta2-integrin adhesion of human eosinophils by phosphoinositide 3-kinase. Am J Respir Cell Mol Biol 2005;33:65-70.
21. Cole AT, Garlick NM, Galvin AM, Hawkey CJ, Robins RA: A flow cytometric method to measure shape change of human neutrophils. Clin Sci 1995;89:549-554.
22. Choi EN, Choi MK, Park CS, Chung IY: A parallel signal-transduction pathway for eotaxin- and interleukin-5-induced eosinophil shape change. Immunology 2003;108:245-256.
23. Georas SN, McIntyre BW, Ebisawa M, Bednarczyk JL, Sterbinsky SA, Schleimer RP, Bochner BS: Expression of a functional laminin receptor (α6β1, very late activation antigen-6) on human eosinophils. Blood 1993;82:2872-2879.
24. Palframan RT, Collins PD, Severs N, Rothery S, Williams TJ, Rankin SM: Mechanisms of acute eosinophil mobilization from the bone marrow stimulated by interleukin-5: the role of specific adhesion molecules and phosphatidylinositol 3-kinase. J Exp Med 1998;188:1621-1632.
25. Kayaba H, Yamada Y, Cui CH, Saito N, Honda K, Kobayashi Y, Urayama O, Chihara J: Expression of VLA-4 on eosinophils decreases in patients with eosinophilia. Int Arch Allergy Immunol 2001;125(suppl 1):33-37.
26. Georas SN, Liu MC, Newman W, Beall LD, Stealey BA, Bochner BS: Altered adhesion molecule expression and endothelial cell activation accompany the recruitment of human granulocytes to the lung after segmental antigen challenge. Am J Respir Cell Mol Biol 1992;7:261-269.
27. Nocker RET, van der Zee JS, Weller FR, van Overveld FJ, Jansen HM, Out TA: Segmental allergen challenge induces plasma protein leakage into the airways of asthmatic subjects at 4 hours but not at 5 minutes after challenge. J Lab Clin Med 1999;134:74-82.
28. Collins DS, Dupurs R, Gleich GJ, Bartemes KR, Koh YY, Pollice M, Albertine KH, Fish JE, Peters SP: Immunoglobulin E-mediated increase in vascular permeability correlates with eosinophilic inflammation. Am Rev Respir Dis 1993;147:677-683.