Crystal structure of the human B-form low molecular weight phosphotyrosyl phosphatase at 1.6-Å resolution

Journal of Biological Chemistry

Volumn 281, Issue 10, 2006, Pages 6520-6527

  Zabell, Adam P R ^a,b   Schroff Jr , Alfred D ^a   Bain, Bornadata Evans ^a   Van Etten, Robert L ^a   Wiest, Olaf ^b   Stauffacher, Cynthia V ^a  

^a PURDUE UNIVERSITY   (United States)

^b UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYMES; HYDROGEN; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NITROGEN COMPOUNDS;

ACTIVATOR RESPONSES; CRYSTAL PACKING; PHOSPHOTYROSYL PHOSPHATASE; SURFACE-EXPOSED ARGININE;

ENZYME KINETICS;

ISOENZYME; PEPTIDE; PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE; ACP1 PROTEIN, HUMAN; ENZYME ACTIVATOR; ENZYME INHIBITOR; NITROPHENOL; NITROPHENYL PHOSPHATE; ONCOPROTEIN; ORGANOPHOSPHORUS COMPOUND; PHOSPHOTYROSINE;

ARTICLE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; HYDROGEN BOND; KINETICS; OPTICAL RESOLUTION; PRIORITY JOURNAL; WILD TYPE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; ENZYME SPECIFICITY; HUMAN; METABOLISM; MOLECULAR WEIGHT; MUTATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; ENZYME ACTIVATORS; ENZYME INHIBITORS; HUMANS; KINETICS; MOLECULAR WEIGHT; MUTATION; NITROPHENOLS; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHOTYROSINE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS; SUBSTRATE SPECIFICITY;

EID: 33646574302     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M506285200     Document Type: Article

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