-
1
-
-
0034466374
-
Human urotensin-II, the most potent mammalian vasoconstrictor identified to date, as a therapeutic target for the management of cardiovascular disease
-
Douglas SA, Ohlstein EH. Human urotensin-II, the most potent mammalian vasoconstrictor identified to date, as a therapeutic target for the management of cardiovascular disease. Trends Cardiovasc Med 2000; 10: 229-37.
-
(2000)
Trends Cardiovasc Med
, vol.10
, pp. 229-237
-
-
Douglas, S.A.1
Ohlstein, E.H.2
-
2
-
-
3042682003
-
Urotensin-II-converting enzyme activity of furin and trypsin in human cells in vitro
-
Russell FD, Kearns P, Toth I, Molenaar P. Urotensin-II-converting enzyme activity of furin and trypsin in human cells in vitro. J Pharmacol Exp Ther 2004; 310: 209-14.
-
(2004)
J Pharmacol Exp Ther
, vol.310
, pp. 209-214
-
-
Russell, F.D.1
Kearns, P.2
Toth, I.3
Molenaar, P.4
-
3
-
-
0002726148
-
Urotensin receptors
-
Girdalstone D, Ed, London, IUPHAR Media
-
Douglas SA, Ohlstein EH. Urotensin receptors. In: Girdalstone D, Ed, The IUPHAR compendium of receptor characterization and classification. London, IUPHAR Media, 2000; 365-72.
-
(2000)
The IUPHAR Compendium of Receptor Characterization and Classification
, pp. 365-372
-
-
Douglas, S.A.1
Ohlstein, E.H.2
-
4
-
-
0036848062
-
Is urotensin-II the new endothelin?
-
Maguire JJ, Davenport AP. Is urotensin-II the new endothelin? Br J Pharmacol 2002; 137: 579-88.
-
(2002)
Br J Pharmacol
, vol.137
, pp. 579-588
-
-
Maguire, J.J.1
Davenport, A.P.2
-
5
-
-
5144219967
-
Cellular distribution of immunoreactive urotensin-II in human tissues with evidence of increased expression in atherosclerosis and a greater constrictor response of small compared to large coronary arteries
-
Maguire JJ, Kuc RE, Wiley KE, Kleinz MJ, Davenport AP. Cellular distribution of immunoreactive urotensin-II in human tissues with evidence of increased expression in atherosclerosis and a greater constrictor response of small compared to large coronary arteries. Peptides 2004; 25: 1767-74.
-
(2004)
Peptides
, vol.25
, pp. 1767-1774
-
-
Maguire, J.J.1
Kuc, R.E.2
Wiley, K.E.3
Kleinz, M.J.4
Davenport, A.P.5
-
6
-
-
4043172801
-
Increased expression of urotensin II and its cognate receptor GPR14 in atherosclerotic lesions of the human aorta
-
Bousette N, Patel L, Douglas SA, Ohlstein EH, Giaid A. Increased expression of urotensin II and its cognate receptor GPR14 in atherosclerotic lesions of the human aorta. Atherosclerosis 2004; 176: 117-23.
-
(2004)
Atherosclerosis
, vol.176
, pp. 117-123
-
-
Bousette, N.1
Patel, L.2
Douglas, S.A.3
Ohlstein, E.H.4
Giaid, A.5
-
7
-
-
5144234214
-
Urotensin II in the cardiovascular system
-
Richards AM, Charles C. Urotensin II in the cardiovascular system. Peptides 2004; 25: 1795-802.
-
(2004)
Peptides
, vol.25
, pp. 1795-1802
-
-
Richards, A.M.1
Charles, C.2
-
8
-
-
0141788726
-
Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure
-
Russell FD, Meyers D, Galbraith AJ, et al. Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure. Am J Physiol Heart Circ Physiol 2003; 285: 1576-81.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
, pp. 1576-1581
-
-
Russell, F.D.1
Meyers, D.2
Galbraith, A.J.3
-
9
-
-
0345731373
-
The expression of urotensin II receptor (U2R) is up-regulated by interferon-g
-
Birker-Robaczewska M, Boukhadra C, Studer R, Mueller C, Binkert C, Nayler O. The expression of urotensin II receptor (U2R) is up-regulated by interferon-g. J Recept Signal Transduct Res 2003; 23: 289-305.
-
(2003)
J Recept Signal Transduct Res
, vol.23
, pp. 289-305
-
-
Birker-Robaczewska, M.1
Boukhadra, C.2
Studer, R.3
Mueller, C.4
Binkert, C.5
Nayler, O.6
-
10
-
-
0037042532
-
Congestive heart failure and expression of myocardial urotensin II
-
Douglas SA, Tayara L, Ohlstein EH, Halawa N, Giaid A. Congestive heart failure and expression of myocardial urotensin II. Lancet 2002; 359: 1990-7.
-
(2002)
Lancet
, vol.359
, pp. 1990-1997
-
-
Douglas, S.A.1
Tayara, L.2
Ohlstein, E.H.3
Halawa, N.4
Giaid, A.5
-
11
-
-
0033575930
-
Human urotensin II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
-
Ames RS, Sarau HM, Douglas SA, et al. Human urotensin II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature 1999;401:282-6.
-
(1999)
Nature
, vol.401
, pp. 282-286
-
-
Ames, R.S.1
Sarau, H.M.2
Douglas, S.A.3
-
12
-
-
3042713965
-
Plasma concentration of urotensin II is raised in hypertension
-
Cheung BM, Leung R, Man YB, Wong LY. Plasma concentration of urotensin II is raised in hypertension. J Hypertens 2004; 22: 1341-4.
-
(2004)
J Hypertens
, vol.22
, pp. 1341-1344
-
-
Cheung, B.M.1
Leung, R.2
Man, Y.B.3
Wong, L.Y.4
-
13
-
-
3142634520
-
The relationship between urotensin II plasma immunoreactivity and left ventricular filling pressures in coronary artery disease
-
Heringlake M, Kox T, Uzun O, et al. The relationship between urotensin II plasma immunoreactivity and left ventricular filling pressures in coronary artery disease. Regul Pept 2004; 121: 129-36.
-
(2004)
Regul Pept
, vol.121
, pp. 129-136
-
-
Heringlake, M.1
Kox, T.2
Uzun, O.3
-
14
-
-
1542316805
-
Elevated plasma human urotensin-II-like immunoreactivity in ischemic cardiomyopathy
-
Lapp H, Boerrigter G, Costello-Boerrigter LC, et al. Elevated plasma human urotensin-II-like immunoreactivity in ischemic cardiomyopathy. Int J Cardiol 2004; 94: 93-7.
-
(2004)
Int J Cardiol
, vol.94
, pp. 93-97
-
-
Lapp, H.1
Boerrigter, G.2
Costello-Boerrigter, L.C.3
-
15
-
-
0037016037
-
Plasma urotensin in human systolic heart failure
-
Ng LL, Loke I, O'Brien RJ, Squire IB, Davies JE. Plasma urotensin in human systolic heart failure. Circulation 2002; 106: 2877-80.
-
(2002)
Circulation
, vol.106
, pp. 2877-2880
-
-
Ng, L.L.1
Loke, I.2
O'Brien, R.J.3
Squire, I.B.4
Davies, J.E.5
-
16
-
-
0037287386
-
Increased plasma urotensin II levels in patients with diabetes mellitus
-
Lond
-
Totsune K, Takahashi K, Arihara Z, Sone M, Ito S, Murakami O. Increased plasma urotensin II levels in patients with diabetes mellitus. Clin Sci (Lond) 2003; 104: 1-5.
-
(2003)
Clin Sci
, vol.104
, pp. 1-5
-
-
Totsune, K.1
Takahashi, K.2
Arihara, Z.3
Sone, M.4
Ito, S.5
Murakami, O.6
-
17
-
-
0035828410
-
Role of urotensin II in patients on dialysis
-
Totsune K, Takahashi K, Arihara Z, et al. Role of urotensin II in patients on dialysis. Lancet 2001; 358: 810-1.
-
(2001)
Lancet
, vol.358
, pp. 810-811
-
-
Totsune, K.1
Takahashi, K.2
Arihara, Z.3
-
18
-
-
0036892492
-
Increased urotensin II plasma levels in patients with cirrhosis and portal hypertension
-
Heller J, Schepke M, Neef M, Woitas R, Rabe C, Sauerbruch T. Increased urotensin II plasma levels in patients with cirrhosis and portal hypertension. J Hepatol 2002; 37: 767-72.
-
(2002)
J Hepatol
, vol.37
, pp. 767-772
-
-
Heller, J.1
Schepke, M.2
Neef, M.3
Woitas, R.4
Rabe, C.5
Sauerbruch, T.6
-
19
-
-
18144374156
-
Increased plasma levels of Urotensin-II in preeclampsia-eclampsia: A new mediator in pathogenesis?
-
Balat O, Aksoy F, Kutlar I, et al. Increased plasma levels of Urotensin-II in preeclampsia-eclampsia: a new mediator in pathogenesis? Eur J Obstet Gynecol Reprod Biol 2005; 120: 33-8.
-
(2005)
Eur J Obstet Gynecol Reprod Biol
, vol.120
, pp. 33-38
-
-
Balat, O.1
Aksoy, F.2
Kutlar, I.3
-
20
-
-
5144230026
-
Urotensin II and cardiovascular diseases
-
Thanassoulis G, Huyhn T, Giaid A. Urotensin II and cardiovascular diseases. Peptides 2004; 25: 1789-94.
-
(2004)
Peptides
, vol.25
, pp. 1789-1794
-
-
Thanassoulis, G.1
Huyhn, T.2
Giaid, A.3
-
21
-
-
10744220750
-
Deletion of the UT receptor gene results in the selective loss of urotensin-II contractile activity in aortae isolated from UT receptor knockout mice
-
Behm DJ, Harrison SM, Douglas SA, et al. Deletion of the UT receptor gene results in the selective loss of urotensin-II contractile activity in aortae isolated from UT receptor knockout mice. Br J Pharmacol 2003; 139: 464-72.
-
(2003)
Br J Pharmacol
, vol.139
, pp. 464-472
-
-
Behm, D.J.1
Harrison, S.M.2
Douglas, S.A.3
-
22
-
-
0035146524
-
Cardiostimulant effects of urotensin-II in human heart in vitro
-
Russell FD, Molenaar P, O'Brien DM. Cardiostimulant effects of urotensin-II in human heart in vitro. Br J Pharmacol 2001; 132: 5-9.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 5-9
-
-
Russell, F.D.1
Molenaar, P.2
O'Brien, D.M.3
-
23
-
-
0033776533
-
Orphan-receptor ligand human urotensin II: Receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1
-
Maguire JJ, Kuc RE, Davenport AP. Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1. Br J Pharmacol 2000; 131: 441-6.
-
(2000)
Br J Pharmacol
, vol.131
, pp. 441-446
-
-
Maguire, J.J.1
Kuc, R.E.2
Davenport, A.P.3
-
24
-
-
2442449621
-
Vasoconstrictive effects of endothelin-1, endothelin-3, and urotensin II in isolated perfused human lungs and isolated human pulmonary arteries
-
Bennett RT, Jones RD, Morice AH, Smith CFC, Cowen ME. Vasoconstrictive effects of endothelin-1, endothelin-3, and urotensin II in isolated perfused human lungs and isolated human pulmonary arteries. Thorax 2004; 59: 401-7.
-
(2004)
Thorax
, vol.59
, pp. 401-407
-
-
Bennett, R.T.1
Jones, R.D.2
Morice, A.H.3
Smith, C.F.C.4
Cowen, M.E.5
-
25
-
-
0036210734
-
Effects of human urotensin II in isolated vessels of various species; comparison with other vasoactive agents
-
Camarda V, Rizzi A, Calo G, et al. Effects of human urotensin II in isolated vessels of various species; comparison with other vasoactive agents. Naunyn-Schmiedeberg's Arch Pharmacol 2002; 365: 141-9.
-
(2002)
Naunyn-Schmiedeberg's Arch Pharmacol
, vol.365
, pp. 141-149
-
-
Camarda, V.1
Rizzi, A.2
Calo, G.3
-
26
-
-
0035853051
-
Effects of urotensin II in human arteries and veins of varying caliber
-
Hillier C, Berry C, Petrie MC, et al. Effects of urotensin II in human arteries and veins of varying caliber. Circulation 2001; 103: 1378-81.
-
(2001)
Circulation
, vol.103
, pp. 1378-1381
-
-
Hillier, C.1
Berry, C.2
Petrie, M.C.3
-
27
-
-
0034996521
-
Potent vasodilator responses to human urotensin-II in human pulmonary and abdominal resistance arteries
-
Stirrat A, Gallagher M, Douglas SA, et al. Potent vasodilator responses to human urotensin-II in human pulmonary and abdominal resistance arteries. Am J Physiol Heart Circ Physiol 2001; 280: H925-8.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
-
-
Stirrat, A.1
Gallagher, M.2
Douglas, S.A.3
-
28
-
-
0013023197
-
Contractile responses to human urotensin-II in rat and human pulmonary arteries: Effect of endothelial factors and chronic hypoxia in the rat
-
MacLean MR, Alexander D, Douglas SA, et al. Contractile responses to human urotensin-II in rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat. Br J Pharmacol 2000; 130: 201-4.
-
(2000)
Br J Pharmacol
, vol.130
, pp. 201-204
-
-
MacLean, M.R.1
Alexander, D.2
Douglas, S.A.3
-
29
-
-
4644306988
-
Emerging roles of urotensin-II in cardiovascular disease
-
Russell FD. Emerging roles of urotensin-II in cardiovascular disease. Pharmacol Ther 2004; 103: 223-43.
-
(2004)
Pharmacol Ther
, vol.103
, pp. 223-243
-
-
Russell, F.D.1
-
30
-
-
0036157935
-
Urotensin II evokes potent vasoconstriction in humans in vivo
-
Bohm F, Pernow J. Urotensin II evokes potent vasoconstriction in humans in vivo. Br J Pharmacol 2002; 135: 25-7.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 25-27
-
-
Bohm, F.1
Pernow, J.2
-
31
-
-
0036163976
-
High plasma concentrations of human urotensin II do not alter local or systemic hemodynamics in man
-
Wilkinson IB, Affolter JT, de Haas SL, et al. High plasma concentrations of human urotensin II do not alter local or systemic hemodynamics in man. Cardiovas Res 2002; 53: 341-7.
-
(2002)
Cardiovas Res
, vol.53
, pp. 341-347
-
-
Wilkinson, I.B.1
Affolter, J.T.2
De Haas, S.L.3
-
32
-
-
26244465123
-
Arrestin-independent internalization and recycling of the urotensin receptor contribute to long-lasting urotensin II-mediated vasoconstriction
-
Giebing G, Tolle M, Jurgensen J, et al. Arrestin-independent internalization and recycling of the urotensin receptor contribute to long-lasting urotensin II-mediated vasoconstriction. Circ Res 2005; 97: 707-15.
-
(2005)
Circ Res
, vol.97
, pp. 707-715
-
-
Giebing, G.1
Tolle, M.2
Jurgensen, J.3
-
33
-
-
0034644865
-
Human urotensin II mediates vasoconstriction via an increase in inositol phosphates
-
Opgaard OS, Nothacker HP, Ehlert FJ, Krause DN. Human urotensin II mediates vasoconstriction via an increase in inositol phosphates. Eur J Pharmacol 2000; 406: 265-71.
-
(2000)
Eur J Pharmacol
, vol.406
, pp. 265-271
-
-
Opgaard, O.S.1
Nothacker, H.P.2
Ehlert, F.J.3
Krause, D.N.4
-
34
-
-
2342656463
-
Mechanism of human urotensin II-induced contraction in rat aorta
-
Tasaki K, Hori M, Ozaki H, Karaki H, Wakabayashi I. Mechanism of human urotensin II-induced contraction in rat aorta. J Pharmacol Sci 2004; 94: 376-83.
-
(2004)
J Pharmacol Sci
, vol.94
, pp. 376-383
-
-
Tasaki, K.1
Hori, M.2
Ozaki, H.3
Karaki, H.4
Wakabayashi, I.5
-
35
-
-
0037040391
-
Human urotensin II-induced aorta ring contractions are mediated by protein kinase C, tyrosine kinases and Rho-kinase: Inhibition by somatostatin receptor antagonists
-
Rossowski WJ, Cheng BL, Taylor JE, Datta R, Coy DH. Human urotensin II-induced aorta ring contractions are mediated by protein kinase C, tyrosine kinases and Rho-kinase: inhibition by somatostatin receptor antagonists. Eur J Pharmacol 2002; 438: 159-70.
-
(2002)
Eur J Pharmacol
, vol.438
, pp. 159-170
-
-
Rossowski, W.J.1
Cheng, B.L.2
Taylor, J.E.3
Datta, R.4
Coy, D.H.5
-
36
-
-
0035827716
-
Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase
-
Sauzeau V, Mellionnec EL, Bertoglio J, Scalbert E, Pacaud P, Loirand G. Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase. Circ Res 2001; 88: 1102-4.
-
(2001)
Circ Res
, vol.88
, pp. 1102-1104
-
-
Sauzeau, V.1
Mellionnec, E.L.2
Bertoglio, J.3
Scalbert, E.4
Pacaud, P.5
Loirand, G.6
-
38
-
-
25144432742
-
Effect of exogenous urotensin-II on vascular tone in skin microcirculation of patients with essential hypertension
-
Sondermeijer B, Kompa A, Komesaroff P, Krum H. Effect of exogenous urotensin-II on vascular tone in skin microcirculation of patients with essential hypertension. Am J Hypertens 2005; 18: 1195-9.
-
(2005)
Am J Hypertens
, vol.18
, pp. 1195-1199
-
-
Sondermeijer, B.1
Kompa, A.2
Komesaroff, P.3
Krum, H.4
-
39
-
-
0037251222
-
Central cardiovascular action of urotensin II in conscious rats
-
Lin Y, Tsuchihashi T, Matsumura K, Abe I, Iida M. Central cardiovascular action of urotensin II in conscious rats. J Hypertens 2003; 21: 159-65.
-
(2003)
J Hypertens
, vol.21
, pp. 159-165
-
-
Lin, Y.1
Tsuchihashi, T.2
Matsumura, K.3
Abe, I.4
Iida, M.5
-
40
-
-
0242441544
-
Central cardiovascular action of urotensin II in spontaneously hypertensive rats
-
Lin Y, Tsuchihashi T, Matsumura K, et al. Central cardiovascular action of urotensin II in spontaneously hypertensive rats. Hypertens Res 2003; 26: 839-45.
-
(2003)
Hypertens Res
, vol.26
, pp. 839-845
-
-
Lin, Y.1
Tsuchihashi, T.2
Matsumura, K.3
-
41
-
-
0041331762
-
Urotensin II acts centrally to increase epinephrine and ACTH release and cause potent inotropic and chronotropic actions
-
Watson AMD, Lambert GW, Smith KJ, May CN. Urotensin II acts centrally to increase epinephrine and ACTH release and cause potent inotropic and chronotropic actions. Hypertension 2003; 42: 373-9.
-
(2003)
Hypertension
, vol.42
, pp. 373-379
-
-
Watson, A.M.D.1
Lambert, G.W.2
Smith, K.J.3
May, C.N.4
-
42
-
-
0036710537
-
Cardiovascular effects of urotensin II in different brain areas
-
Lu Y, Zou CJ, Huang DW, Tang CS. Cardiovascular effects of urotensin II in different brain areas. Peptides 2002; 23: 1631-5.
-
(2002)
Peptides
, vol.23
, pp. 1631-1635
-
-
Lu, Y.1
Zou, C.J.2
Huang, D.W.3
Tang, C.S.4
-
43
-
-
4644365094
-
A radioimmunoassay to detect urotensin II in the plasma of rat models of hypertension
-
Song W, Ashton N, Balment RJ. A radioimmunoassay to detect urotensin II in the plasma of rat models of hypertension. J Physiol 2002; 544P: S024.
-
(2002)
J Physiol
, vol.544 P
-
-
Song, W.1
Ashton, N.2
Balment, R.J.3
-
44
-
-
0142243355
-
A comparison of cerebrospinal fluid and plasma urotensin II concentrations in normotensive and hypertensive patients undergoing urological surgery during spinal anesthesia: A pilot study
-
Thompson JP, Watt P, Sanghavi S, Strupish JW, Lambert DG. A comparison of cerebrospinal fluid and plasma urotensin II concentrations in normotensive and hypertensive patients undergoing urological surgery during spinal anesthesia: a pilot study. Anesth Analg 2003; 97: 1501-3.
-
(2003)
Anesth Analg
, vol.97
, pp. 1501-1503
-
-
Thompson, J.P.1
Watt, P.2
Sanghavi, S.3
Strupish, J.W.4
Lambert, D.G.5
-
45
-
-
0035208378
-
Co-expression of urotensin II and its receptor (GPR14) in human cardiovascular and renal tissues
-
Matsushita M, Shichiri M, Imai T, et al. Co-expression of urotensin II and its receptor (GPR14) in human cardiovascular and renal tissues. J Hypertens 2001; 19: 2185-90.
-
(2001)
J Hypertens
, vol.19
, pp. 2185-2190
-
-
Matsushita, M.1
Shichiri, M.2
Imai, T.3
-
46
-
-
33645937651
-
Expression of urotensin II and Gprotein coupled receptor 14 mRNA in human pheochromocytoma tissues
-
Liu GQ, Zeng ZP, Li HZ, et al. Expression of urotensin II and Gprotein coupled receptor 14 mRNA in human pheochromocytoma tissues. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2005; 27: 457-60.
-
(2005)
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
, vol.27
, pp. 457-460
-
-
Liu, G.Q.1
Zeng, Z.P.2
Li, H.Z.3
-
47
-
-
0042071570
-
Role of urotensin II gene in genetic susceptibility to type 2 diabetes mellitus in Japanese subjects
-
Wenyi Z, Suzuki S, Hirai M, et al. Role of urotensin II gene in genetic susceptibility to type 2 diabetes mellitus in Japanese subjects. Diabetologia 2003; 46: 972-6.
-
(2003)
Diabetologia
, vol.46
, pp. 972-976
-
-
Wenyi, Z.1
Suzuki, S.2
Hirai, M.3
-
48
-
-
5144234639
-
Genetic variations at urotensin II and urotensin II receptor genes and risk of type 2 diabetes mellitus in Japaneses
-
Suzuki S, Wenyi Z, Hirai M, et al. Genetic variations at urotensin II and urotensin II receptor genes and risk of type 2 diabetes mellitus in Japaneses. Peptides 2004; 25: 1803-8.
-
(2004)
Peptides
, vol.25
, pp. 1803-1808
-
-
Suzuki, S.1
Wenyi, Z.2
Hirai, M.3
-
49
-
-
5144231012
-
Elevated plasma levels of immunoreactive urotensin II and its increased urinary excretion in patients with type 2 diabetes mellitus: Association with progress of diabetic nephropathy
-
Totsune K, Takahashi K, Arihara Z, et al. Elevated plasma levels of immunoreactive urotensin II and its increased urinary excretion in patients with type 2 diabetes mellitus: association with progress of diabetic nephropathy. Peptides 2004; 25: 1809-14.
-
(2004)
Peptides
, vol.25
, pp. 1809-1814
-
-
Totsune, K.1
Takahashi, K.2
Arihara, Z.3
-
50
-
-
7444244979
-
Increased expression of urotensin II and urotensin II receptor in human diabetic nephrophathy
-
Langham RG, Kelly DJ, Gow RM, et al. Increased expression of urotensin II and urotensin II receptor in human diabetic nephrophathy. Am J Kidney Dis 2004; 44: 826-31.
-
(2004)
Am J Kidney Dis
, vol.44
, pp. 826-831
-
-
Langham, R.G.1
Kelly, D.J.2
Gow, R.M.3
-
51
-
-
0036176365
-
Insulin resistance and vascular function
-
Baron AD. Insulin resistance and vascular function. J Diabetes Complications 2002; 16: 92-102.
-
(2002)
J Diabetes Complications
, vol.16
, pp. 92-102
-
-
Baron, A.D.1
-
52
-
-
0034941634
-
Inhibition of insulin release by urotensin II - A study on the perfused rat pancreas
-
Silvestre RA, Rodriguez-Gallardo J, Egido EM, Marco J. Inhibition of insulin release by urotensin II - a study on the perfused rat pancreas. Horm Metab Res 2001; 33: 379-81.
-
(2001)
Horm Metab Res
, vol.33
, pp. 379-381
-
-
Silvestre, R.A.1
Rodriguez-Gallardo, J.2
Egido, E.M.3
Marco, J.4
-
53
-
-
11844271454
-
Urotensin-II is present in pancreatic extracts and inhibits insulin release in the perfused rat pancreas
-
Silvestre RA, Egido EM, Hernandez R, et al. Urotensin-II is present in pancreatic extracts and inhibits insulin release in the perfused rat pancreas. Eur J Endocrinol 2004; 151: 803-9.
-
(2004)
Eur J Endocrinol
, vol.151
, pp. 803-809
-
-
Silvestre, R.A.1
Egido, E.M.2
Hernandez, R.3
-
54
-
-
0035200903
-
Vasoconstrictor activity of novel endothelin peptide, ET-1 (1-31), in human mammary and coronary arteries in vitro
-
Maguire JJ, Kuc RE, Davenport AP. Vasoconstrictor activity of novel endothelin peptide, ET-1 (1-31), in human mammary and coronary arteries in vitro. Br J Pharmacol 2001; 134: 1360-6.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 1360-1366
-
-
Maguire, J.J.1
Kuc, R.E.2
Davenport, A.P.3
-
55
-
-
0023216566
-
Effects of somatostatin-25 and urotensin II on lipid and carbohydrate metabolism of coho salmon, Oncorhynchus kisutch
-
Sheridan MA, Plisetskaya EM, Bern HA, Gorbman A. Effects of somatostatin-25 and urotensin II on lipid and carbohydrate metabolism of coho salmon, Oncorhynchus kisutch. Gen Comp Endocrinol 1987; 66: 405-14.
-
(1987)
Gen Comp Endocrinol
, vol.66
, pp. 405-414
-
-
Sheridan, M.A.1
Plisetskaya, E.M.2
Bern, H.A.3
Gorbman, A.4
-
56
-
-
0022568918
-
Both somatostatin and the caudal neuropeptide, urotensin II, stimulate lipid mobilization from coho salmon liver incubated in vitro
-
Sheridan MA, Bern HA. Both somatostatin and the caudal neuropeptide, urotensin II, stimulate lipid mobilization from coho salmon liver incubated in vitro. Regul Pept 1986; 14: 333-44.
-
(1986)
Regul Pept
, vol.14
, pp. 333-344
-
-
Sheridan, M.A.1
Bern, H.A.2
-
57
-
-
1642463375
-
Translational medicine in fish-derived peptides: From fish endocrinology to human physiology and diseases
-
Takahashi K. Translational medicine in fish-derived peptides: from fish endocrinology to human physiology and diseases. Endocr J 2004; 51: 1-17.
-
(2004)
Endocr J
, vol.51
, pp. 1-17
-
-
Takahashi, K.1
-
58
-
-
33646542569
-
Behavioral effects of urotensin-II centrally administered in mice
-
Berl
-
Do-Rego JC, Chatenet D, Orta MH, et al. Behavioral effects of urotensin-II centrally administered in mice. Psychopharmacology (Berl) 2005; 14: 1-15.
-
(2005)
Psychopharmacology
, vol.14
, pp. 1-15
-
-
Do-Rego, J.C.1
Chatenet, D.2
Orta, M.H.3
-
59
-
-
12144289670
-
Intracerebroventricular administration of urotensin II promotes anxiogenic-like behaviors in rodents
-
Matsumoto Y, Abe M, Watanabe T, et al. Intracerebroventricular administration of urotensin II promotes anxiogenic-like behaviors in rodents. Neurosci Lett 2004; 358: 99-102.
-
(2004)
Neurosci Lett
, vol.358
, pp. 99-102
-
-
Matsumoto, Y.1
Abe, M.2
Watanabe, T.3
-
60
-
-
16544365596
-
Discovery and clinical implications of urotensin II
-
Naruse M, Nagata D, Tanabe A, Imaki T. Discovery and clinical implications of urotensin II. Nippon Rinsho 2004; 62 Suppl 9: 685-93.
-
(2004)
Nippon Rinsho
, vol.62
, Issue.9 SUPPL.
, pp. 685-693
-
-
Naruse, M.1
Nagata, D.2
Tanabe, A.3
Imaki, T.4
-
61
-
-
0036157998
-
Effect of chronic hypoxia on contents of urotensin II and its functional receptors in rat myocardium
-
Zhang Y, Li J, Cao J, et al. Effect of chronic hypoxia on contents of urotensin II and its functional receptors in rat myocardium. Heart Vessels 2002; 16: 64-8.
-
(2002)
Heart Vessels
, vol.16
, pp. 64-68
-
-
Zhang, Y.1
Li, J.2
Cao, J.3
-
62
-
-
19544371884
-
Urotensin II in patients with chronic heart failure
-
Kruger S, Graf J, Kunz D, et al. Urotensin II in patients with chronic heart failure. Eur J Heart Fail 2005; 7: 475-8.
-
(2005)
Eur J Heart Fail
, vol.7
, pp. 475-478
-
-
Kruger, S.1
Graf, J.2
Kunz, D.3
-
64
-
-
27944438077
-
Expression of urotensin-II in human coronary atherosclerosis
-
Hassan GS, Douglas SA, Ohlstein EH, Giaid A. Expression of urotensin-II in human coronary atherosclerosis. Peptides 2005; 26: 2464-72.
-
(2005)
Peptides
, vol.26
, pp. 2464-2472
-
-
Hassan, G.S.1
Douglas, S.A.2
Ohlstein, E.H.3
Giaid, A.4
-
65
-
-
0036671721
-
G-proteincoupled receptors in human atherosclerosis: Comparison of vasoconstrictors (endothelin and thromboxane) with recently deorphanized (urotensin-II, apelin and ghrelin) receptors
-
Katugampola SD, Kuc RE, Maguire JJ, Davenport. G-proteincoupled receptors in human atherosclerosis: comparison of vasoconstrictors (endothelin and thromboxane) with recently deorphanized (urotensin-II, apelin and ghrelin) receptors. Clin Sci 2002; 103: 171S-5S.
-
(2002)
Clin Sci
, vol.103
-
-
Katugampola, S.D.1
Kuc, R.E.2
Maguire, J.J.3
Davenport4
-
66
-
-
0035370567
-
Human urotensin II increases coronary perfusion pressure in the isolated rat heart: Potentiation by nitric oxide synthase and cyclooxygenase inhibition
-
Gray GA, Jones MR, Sharif I. Human urotensin II increases coronary perfusion pressure in the isolated rat heart: potentiation by nitric oxide synthase and cyclooxygenase inhibition. Life Sci 2001; 69: 175-80.
-
(2001)
Life Sci
, vol.69
, pp. 175-180
-
-
Gray, G.A.1
Jones, M.R.2
Sharif, I.3
-
67
-
-
27644465919
-
Role of prostaglandins in urotensin II-induced vasodilatation in the coronary arteries of aged rats
-
Ishihata A, Ogaki T, Aita T, Katano Y. Role of prostaglandins in urotensin II-induced vasodilatation in the coronary arteries of aged rats. Eur J Pharmacol 2005; 523: 119-26.
-
(2005)
Eur J Pharmacol
, vol.523
, pp. 119-126
-
-
Ishihata, A.1
Ogaki, T.2
Aita, T.3
Katano, Y.4
-
68
-
-
0034799815
-
Comparison of the contractile responses of human coronary bypass grafts and monkey arteries to human urotensin-II
-
Paysant J, Rupin A, Simonet S, Fabiani JN, Verbeuren TJ. Comparison of the contractile responses of human coronary bypass grafts and monkey arteries to human urotensin-II. Fundam Clin Pharmacol 2001; 15: 227-31.
-
(2001)
Fundam Clin Pharmacol
, vol.15
, pp. 227-231
-
-
Paysant, J.1
Rupin, A.2
Simonet, S.3
Fabiani, J.N.4
Verbeuren, T.J.5
-
69
-
-
0042324172
-
Effects of urotensin II on isolated rat hearts under normal perfusion and ischemia reperfusion
-
Zhou P, Wu SY, Yu CF, et al. Effects of urotensin II on isolated rat hearts under normal perfusion and ischemia reperfusion. Sheng Li Xue Bao 2003; 55: 442-8.
-
(2003)
Sheng Li Xue Bao
, vol.55
, pp. 442-448
-
-
Zhou, P.1
Wu, S.Y.2
Yu, C.F.3
-
70
-
-
11144313355
-
Urotensin-II-mediated cardiomyocyte hypertrophy: Effect of receptor antagonism and role of inflammatory mediators
-
Johns DG, Ao Z, Naselsky D, et al. Urotensin-II-mediated cardiomyocyte hypertrophy: effect of receptor antagonism and role of inflammatory mediators. Naunyn Schmiedebergs Arch Pharmacol 2004; 370: 238-50.
-
(2004)
Naunyn Schmiedebergs Arch Pharmacol
, vol.370
, pp. 238-250
-
-
Johns, D.G.1
Ao, Z.2
Naselsky, D.3
-
71
-
-
1842611621
-
Human urotensin-II enhances plasma extravasation in specific vascular districts in Wistar rats
-
Gendron G, Simard B, Gobeil F Jr, Sirois P, D'Orleans-Juste P, Regoli D. Human urotensin-II enhances plasma extravasation in specific vascular districts in Wistar rats. Can J Pysiol Pharmacol 2004; 82: 16-21.
-
(2004)
Can J Pysiol Pharmacol
, vol.82
, pp. 16-21
-
-
Gendron, G.1
Simard, B.2
Gobeil Jr., F.3
Sirois, P.4
D'Orleans-Juste, P.5
Regoli, D.6
-
72
-
-
7444265142
-
Human urotensin II modulates collagen synthesis and the expression of MMP-1 in human endothelial cells
-
Wang H, Mehta JL, Chen K, Zhang X, Li D. Human urotensin II modulates collagen synthesis and the expression of MMP-1 in human endothelial cells. J Cardiovasc Pharmacol 2004; 44: 577-81.
-
(2004)
J Cardiovasc Pharmacol
, vol.44
, pp. 577-581
-
-
Wang, H.1
Mehta, J.L.2
Chen, K.3
Zhang, X.4
Li, D.5
-
73
-
-
31944451269
-
Human urotensin II accelerates foam cell formation in human monocyte-derived macrophages
-
Watanabe T, Suguro T, Miyazaki A, et al. Human urotensin II accelerates foam cell formation in human monocyte-derived macrophages. Hypertension 2005; 46: 738-44.
-
(2005)
Hypertension
, vol.46
, pp. 738-744
-
-
Watanabe, T.1
Suguro, T.2
Miyazaki, A.3
-
74
-
-
2942703937
-
Up-regulation of acylcoenzyme A:cholesterol acyltransferase-1 by transforming growth factor-β1 during differentiation of human monocytes into macrophages
-
Hori M, Miyazaki A, Tamagawa H, et al. Up-regulation of acylcoenzyme A:cholesterol acyltransferase-1 by transforming growth factor-β1 during differentiation of human monocytes into macrophages. Biochem Biophys Res Commun 2004; 320: 501-5.
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 501-505
-
-
Hori, M.1
Miyazaki, A.2
Tamagawa, H.3
-
75
-
-
33646576752
-
Serotonin acts as an upregulator of acyl-coenzyme A:cholesterol acyltransferase-1 in human monocyte-macrophages
-
in press
-
Suguro T, Watanabe T, Miyazaki A, et al. Serotonin acts as an upregulator of acyl-coenzyme A:cholesterol acyltransferase-1 in human monocyte-macrophages. Atherosclerosis 2005; in press.
-
(2005)
Atherosclerosis
-
-
Suguro, T.1
Watanabe, T.2
Miyazaki, A.3
-
76
-
-
1842689809
-
Adiponectin downregulates acyl-coenzyme A:cholesterol acyltransferase-1 in cultured human monocyte-derived macrophages
-
Furukawa K, Hori M, Miyazaki A, et al. Adiponectin downregulates acyl-coenzyme A:cholesterol acyltransferase-1 in cultured human monocyte-derived macrophages. Biochem Biophys Res Commun 2004; 317: 831-6.
-
(2004)
Biochem Biophys Res Commun
, vol.317
, pp. 831-836
-
-
Furukawa, K.1
Hori, M.2
Miyazaki, A.3
-
77
-
-
0035800017
-
Synergistic effect of urotensin II with mildly oxidized LDL on DNA synthesis in vascular smooth muscle cells
-
Watanabe T, Pakala R, Katagiri T, Benedict CR. Synergistic effect of urotensin II with mildly oxidized LDL on DNA synthesis in vascular smooth muscle cells. Circulation 2001; 104: 16-8.
-
(2001)
Circulation
, vol.104
, pp. 16-18
-
-
Watanabe, T.1
Pakala, R.2
Katagiri, T.3
Benedict, C.R.4
-
78
-
-
0035208577
-
Synergistic effect of urotensin II with serotonin on vascular smooth muscle cell proliferation
-
Watanabe T, Pakala R, Katagiri T, Benedict CR. Synergistic effect of urotensin II with serotonin on vascular smooth muscle cell proliferation. J Hypertens 2001; 19: 2191-6.
-
(2001)
J Hypertens
, vol.19
, pp. 2191-2196
-
-
Watanabe, T.1
Pakala, R.2
Katagiri, T.3
Benedict, C.R.4
-
79
-
-
0037449368
-
Urotensin II-induced activation of extracellular signalregulated kinase in cultured vascular smooth muscle cells: Involvement of cell adhesion-mediated integrin signaling
-
Tamura K, Okazaki M, Tamura M, Isozumi K, Tasaki H, Nakashima Y. Urotensin II-induced activation of extracellular signalregulated kinase in cultured vascular smooth muscle cells: involvement of cell adhesion-mediated integrin signaling. Life Sci 2003; 72: 1049-60.
-
(2003)
Life Sci
, vol.72
, pp. 1049-1060
-
-
Tamura, K.1
Okazaki, M.2
Tamura, M.3
Isozumi, K.4
Tasaki, H.5
Nakashima, Y.6
-
80
-
-
14644433774
-
Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cells
-
Djordjevic T, BelAiba RS, Bonello S, Pfeilschifter J, Hess J, Gorlach A. Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cells. Arterioscler Thromb Vasc Biol 2005; 25: 519-25.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 519-525
-
-
Djordjevic, T.1
BelAiba, R.S.2
Bonello, S.3
Pfeilschifter, J.4
Hess, J.5
Gorlach, A.6
-
81
-
-
26844477614
-
A role for urotensin II in restenosis following balloon angioplasty: Use of a selective UT receptor blocker
-
Rakowski E, Hassan GS, Dhanak D, Ohlstein EH, Douglas SA, Giaid A. A role for urotensin II in restenosis following balloon angioplasty: use of a selective UT receptor blocker. J Moll Cell Cardiol 2005;39:785-91.
-
(2005)
J Moll Cell Cardiol
, vol.39
, pp. 785-791
-
-
Rakowski, E.1
Hassan, G.S.2
Dhanak, D.3
Ohlstein, E.H.4
Douglas, S.A.5
Giaid, A.6
-
82
-
-
0037385602
-
Human urotensin-II as a novel cardiovascular target: 'heart' of the matter or simply a fishy 'tail'?
-
Douglas SA. Human urotensin-II as a novel cardiovascular target: 'heart' of the matter or simply a fishy 'tail'? Curr Opin Pharmacol 2003; 3: 159-67.
-
(2003)
Curr Opin Pharmacol
, vol.3
, pp. 159-167
-
-
Douglas, S.A.1
-
83
-
-
0012892221
-
The peptidic somatostatin analogs lanreotide, BIM-23127 and BIM-23042 are urotensin-II receptor ligands
-
Herold CL, Behm DJ, Buckley PT, Foley JJ, Douglas SA. The peptidic somatostatin analogs lanreotide, BIM-23127 and BIM-23042 are urotensin-II receptor ligands. Pharmacologist 2002; 44: 170-1.
-
(2002)
Pharmacologist
, vol.44
, pp. 170-171
-
-
Herold, C.L.1
Behm, D.J.2
Buckley, P.T.3
Foley, J.J.4
Douglas, S.A.5
-
84
-
-
0037171726
-
Identification of nonpeptidic urotensin II receptor antagonists by virtual screening based on a pharmacophore model derived from structure-activity relationships and nuclear magnetic resonance studies on urotensin II
-
Flohr S, Kurz M, Kostenis E, Brkovich A, Fournier A, Klabunde T. Identification of nonpeptidic urotensin II receptor antagonists by virtual screening based on a pharmacophore model derived from structure-activity relationships and nuclear magnetic resonance studies on urotensin II. J Med Chem 2002; 45: 1799-1805.
-
(2002)
J Med Chem
, vol.45
, pp. 1799-1805
-
-
Flohr, S.1
Kurz, M.2
Kostenis, E.3
Brkovich, A.4
Fournier, A.5
Klabunde, T.6
-
85
-
-
4644332005
-
Pharmacology of the urotensin-II receptor antagonist Palosuran (ACT-058362; 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl- quinolin-4-yl)-urea sulfate salt): First demonstration of a pathophysiological role of the urotensin system
-
Clozel M, Binkert C, Birker-Robaczewska M, et al. Pharmacology of the urotensin-II receptor antagonist Palosuran (ACT-058362; 1-[2-(4-benzyl-4- hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea sulfate salt): first demonstration of a pathophysiological role of the urotensin system. J Pharmacol Exp Ther 2004; 311: 204-12.
-
(2004)
J Pharmacol Exp Ther
, vol.311
, pp. 204-212
-
-
Clozel, M.1
Binkert, C.2
Birker-Robaczewska, M.3
-
86
-
-
33644754588
-
The urotensin-II receptor antagonist palosuran improves pancreatic and renal function in diabetic rats
-
in press
-
Clozel M, Hess P, Qiu C, Ding SS, Rey M. The urotensin-II receptor antagonist palosuran improves pancreatic and renal function in diabetic rats. J Pharmacol Exp Ther 2005; in press.
-
(2005)
J Pharmacol Exp Ther
-
-
Clozel, M.1
Hess, P.2
Qiu, C.3
Ding, S.S.4
Rey, M.5
-
87
-
-
1642368204
-
Urantide: An ultrapotent urotensin II antagonist peptide in the rat aorta
-
Patacchini R, Santicioli P, Giuliani S, et al. Urantide: an ultrapotent urotensin II antagonist peptide in the rat aorta. Br J Pharmacol 2003; 140: 1155-8.
-
(2003)
Br J Pharmacol
, vol.140
, pp. 1155-1158
-
-
Patacchini, R.1
Santicioli, P.2
Giuliani, S.3
|