Enantioselective routes to (-)-(R)-muscone

Synlett

Volumn , Issue 7, 2006, Pages 1031-1034

  Bulic, Bruno ^a   Lücking, Ulrich ^a   Pfaltz, Andreas ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Asymmetric catalysis; Copper; Macrocycles; Muscone; Palladium

Indexed keywords

14 METHYLCYCLODEC 2 ENONE; ALKYNE DERIVATIVE; CYCLOALKANONE; CYCLOPENTADEC 2 ENONE; CYCLOPENTADECA 2,14 DIENONE; DECANOL; DIMETHYL ZINC; HEXADECA 1,15 DIYNE; MACROCYCLIC COMPOUND; MUSCONE; UNCLASSIFIED DRUG; ZINC DERIVATIVE;

ADDITION REACTION; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CYCLIZATION; ENANTIOSELECTIVITY; STEREOISOMERISM; STRUCTURE ANALYSIS;

EID: 33646572891     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-939069     Document Type: Article

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22. f = 0.45 (hexane-EtOAc, 9:1).
23. f = 0.55 (hexane-EtOAc, 9:1). HPLC (250 mm x 4.6 mm, Daicel, Chiracel AS, detection at 223 nm, hexane-i-PrOH 98.5:1.5, 0.5 mL/min, 293K): 21.1 min (R), 24.1 min (S).