Accuracy of diagnosis of protein S deficiency by protein S activity and antigen assays

Journal of Clinical Ligand Assay

Volumn 28, Issue 3, 2005, Pages 130-135

  Marlar, Richard A ^a,b,d   Potts, Robyn M ^b   Welsh, Carolyn H ^c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

Clinical assays; Genetic deficiency; Protein S

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 8; PROTEIN S;

ANTIGEN DETECTION; ARTICLE; ASSAY; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC APPROACH ROUTE; DIAGNOSTIC VALUE; HEMOSTASIS; HIGH RISK PATIENT; HUMAN; INNATE IMMUNITY; PROTEIN FUNCTION; PROTEIN S DEFICIENCY; REFERENCE VALUE; SERODIAGNOSIS; THROMBOPHILIA; THROMBOSIS;

EID: 33646572258     PISSN: 10811672     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Esmon CT: Protein C, protein S and thrombomodulin. In: Colman RW, Marder VJ, Clowes AW, George JN, Goldhaber SZ (eds). Hemostasis and Thrombosis; Basic Principles and Clinical Practice. 5th edn. Philadelphia: Lippincott, Williams and Wilkins; 2006:249-269.
2. Rigby AC, Grant MA: Protein S a conduit between anticoagulation and inflammation. Crit Care Med 2004;32:(Suppl)S336-S341.
3. Heeb MJ, Koenen RR, Fernandez JA, Hackeng TM: Direct anticoagulant activity of protein S-C4b binding protein complex in Heerlen heterozygotes and normals. J Thromb Haemostasis 2004;2:1766-1773.
4. Esmon CT: New mechanisms for vascular control of inflammation mediated by natural anticoagulant proteins. J Exp Med 2002;196:561-564.
5. Dahlback B: Protein S and C4b-binding protein: components involved in the regulation of the protein C anticoagulant system. Thromb Haemostasis 1991;66:49-61.
6. Walker ID, Greaves M, Preston FE: Investigations and management of heritable thrombophilia. Br J Haematol 2001;114:512-528.
7. Brouwer JL, Veeger NJ, van der Schaaf W, et al.: Difference in absolute risk of venous and arterial thrombosis between familial protein S deficiency type I and type III. Results from a family cohort study to assess the clinical impact of a laboratory test-based classification. Br J Haematol 2006;128:703-710.
8. Jennings I, Kitchen S, Cooper P, et al.: Sensitivity of functional proteins assays to protein S deficiency: a comparative study of three commercial kits. J Thromb Haemostasis 2003;1:1112-1114.
9. Van Cott EM, Ledford-Kraemer M, Meijer P, et al.: NASCOLA Proficiency Testing Committee. Protein S assays: an analysis of North American Specialized Coagulation Laboratory Association proficiency testing. Am J Clin Path 2005;123:778-785.
10. Favaloro EJ: Learning from peer assessment: the role of the external quality assurance multi-laboratory thrombophilia test process. Semin Thromb Hemostasis 2005;31:85-89.
11. Meijer P, Haverkate F: External quality assessment and the laboratory diagnosis of thrombophilia. Semin Thromb Hemostasis 2005;31:59-65.
12. Tripodi A: A review of the clinical and diagnostic utility of laboratory tests for the detection of congenital thrombophilia. Semin Thromb Hemostasis 2005;31:25-32.
13. Labrouche S, Reboul MP, Guerin V, et al.: Protein C and protein S assessment in hospital laboratories: which strategy and what role for DNA sequencing? Blood Coag Fibrinolysis 2003;14:531-538.
14. Koenen RR, Christella M, Thomassen LG, et al.: Effect of oral contraceptives on the anticoagulant activity of protein S in plasma. Thromb Haemostasis 2005;93:853-859.
15. Persson KE, Dahlback B, Hillarp A: Diagnosing protein S deficiency: analytical considerations. Clin Lab 2003;49:103-110.
16. Comp PC: Laboratory evaluation of protein S status. Scmin Thromb Hemostasis 1990;16:177-181.
17. Aillaud MF, Pouymayou K, Brunet D, et al.: New direct assay of free protein S antigen applied to diagnosis of protein S deficiency. Thromb Haemostasis 1996;75:283-285.
18. Comp PC, Thurnau GR, Welsh J, Esmon CT: Functional and immunologic protein S levels are decreased during pregnancy. Blood 1986;68:881-885.
19. Beauchamp NJ, Dykes AC, Parikh N, et al.: The prevalence of, and molecular defects underlying, inherited protein S deficiency in the general population. Br J Haematol 2004;125:647-654.
20. Graf LL, Welsh CH, Qamar Z, Marlar RA: Activated protein C resistance assay detects thrombotic risk factors other than factor V Leiden. Am J Clin Pathol 2003;119:52-60.
21. Castellone D: Coagulation: the good, the bad and the unacceptable. Adv Admin Lab. 1999:53-55.
22. Jensen R, Fritsma GA: Preanalytical variables in the coagulation laboratory. Adv Lab Managers. 2000:90-94.
23. Lane DA, Mannucci PM, Bauer KA, et al.: Inherited thrombophilia: Part I. Thromb Haemostasis 1996;76:651-662.