Bacterial contamination of blood components - Incidence and significance for homologous and autologous transfusion

LaboratoriumsMedizin

Volumn 30, Issue 2, 2006, Pages 66-73

  Walther Wenke, Gabriele ^a  

^a DRK Blutspendedienst West   (Germany)

Author keywords

Bacterial contamination; Bacterial detection; Transfusion associated sepsis

Indexed keywords

THROMBOCYTE CONCENTRATE;

BACTERIAL INFECTION; BACTERIUM CONTAMINATION; BACTERIUM CULTURE; BACTERIUM DETECTION; BLOOD AUTOTRANSFUSION; BLOOD COMPONENT THERAPY; BLOOD SAMPLING; BLOOD TRANSFUSION; BLOOD TRANSFUSION REACTION; GERMANY; HUMAN; INCIDENCE; PATIENT MONITORING; PATIENT SAFETY; REVIEW; RISK REDUCTION; SEPSIS;

BACTERIA (MICROORGANISMS);

EID: 33646560313     PISSN: 03423026     EISSN: 14390477     Source Type: Journal    
DOI: 10.1515/JLM.2006.011     Document Type: Review

References (49)

1. Perez P, Salmi R, Folléa G, Schmit J, De Barbeyrac B, Sudre P, et al. Transfusion-associated bacterial contamination: Description of 41 cases from the French national case-control study (Bacthem) [abstract]. Transfusion 1999;39(Suppl):2S.
2. Arduino MJ, Bland LA, Tipple MA, Aguero SM, Favero MS, Jarvis WR. Growth and endotoxin production of Yersinia enterocolitica und Enterobacter agglomerans in packed erythrocytes. J Clin Microbiol 1989;27:1483-5.
3. Goldman M, Blajchman MA. Bacterial contamination. In: Popovsky MA, editor. Transfusion reactions, 2nd ed. Bethesda, MD: AABB Press 2001:129-54.
4. Yomtovian R, Lazarus HM, Goodnough LT, Hirschler NV, Morrissey AM, Jacobs MR. A prospective microbiologic surveillance program to detect and prevent the transfusion of bacterially contaminated platelets. Transfusion 1993;33:902-9.
5. Chiu EK, Yuen KY, Lie AK, Liang R, Lau YL, Lee ACW, et al. A prospective study on symptomatic bacteremia from platelet transfusion and its management. Transfusion 1994;34:950-65.
6. Wagner SJ, Moroff G, Katz AJ, Friedmann LI. Comparison of bacteria growth in single and pooled platelet concentrates after deliberate inoculation and storage. Transfusion 1995;35:298-302.
7. Goldman M, Blajchman MA. Blood product-associated bacterial sepsis. Transfus Med Rev 1991;5:75-83.
8. Kuehnert MJ, Roth VR, Haley NR, Gregory KR, Elder KV, Schreiber GB, et al. Transfusion-transmitted bacterial infection in the United States, 1998 through 2000. Transfusion 2001;41:1493-9.
9. Yomtovian R, Palavecino E. Bacterial contamination of blood components - history and epidemiology. In: Brecher ME, editor. Bacterial and parasitic contamination of blood components. Bethesda, MD: AABB Press 2003:1-30.
10. Richards C, Kolins J, Trindale CD. Autologous transfusion-transmitted Yersinia enterocolitica [letter]. J Am Med Assoc 1992;268:1541-2.
11. Sire JM, Michelet C, Mesnard R, Tardivel R, Minet J, Bracq H, et al. Septic shock due to Yersinia enterocolitica after autologous transfusion (letter). Clin Infect Dis 1993;17:954-5.
12. Duncan KL, Ransley J, Elterman M. Transfusion-transmitted Serratia liquifaciens from an autologous blood unit [let-ter]. Transfusion 1994;34:738-9.
13. Haditsch M, Binder L, Gabriel C, Müller-Uri P, Watschinger R, Mittermayer H. Yersinia enterocolitica septicemia in autologous blood transfusion. Transfusion 1994;34:907-9.
14. Graul A, Heiden M, Gräf K, Keller-Stanislawski B. Hämovigilanz in Deutschland - Berichte aus dem Paul-Ehrlich-Institut über Verdachtsfälle von Transfusionsreaktionen im Beobachtungszeitraum Januar 1995 bis Dezember 2002. Transfus Med Hemother 2003;30:232-8.
15. Andreu G, Morel P, Forestier F, Debeir J, Rebibo D, Janvier G, et al. Hemovigilance network in France: organisation and analysis of immediate transfusion incident reports from 1994 to 1998. Transfusion 2002;42:1356-64.
16. Serious hazards of transfusion (SHOT). Annual report 2004. http://www.shotuk.org.
17. Bundesärztekammer. Leitlinien zur Therapie mit Blutkomponenten und Plasmaderivaten. Deutscher Ärzte-Verlag Köln 2003.
18. Bundesärztekammer, Paul-Ehrlich-Institut. Richtlinien zur Gewinnung von Blut und Blutbestandteilen und zur Anwendung von Blutprodukten (Hämotherapie). Deutscher Ärzte-Verlag Köln 2005.
19. Goodnough LT, Shander A, Brecher ME. Transfusion medicine: looking into the future. Lancet 2003;361:161-9.
20. Downes KA, Yomtovian R. Advances in pretransfusion infections disease testing: ensuring the safety of transfusion therapy. Clin Lab Med 2002;22:475-90.
21. Walther-Wenke G, Doerner R, Montag-Lessing T, Lange H, Baerbel B, Walter D, et al. Working party on "Microbiologic investigations in transfusion medicine of the advisory board of the German Ministry of Health (Arbeitskreis Blut)". Bacterial contamination of blood components: Results of a two-year survey in Germany [abstract]. Transfusion 1999;39(Suppl 1).
22. Montag T, Baumann B, Dörner R, Exner M, Heinz HP, Lange H, et al. Mitteilungen des Arbeitskreises Blut des Bundesministeriums für Gesundheit: Mindestanforderungen zur Sterilitätstestung (Test auf Kontamination durch Bakterien und Pilze) von Blutkomponenten (Zellkonzentrate, Gefrorenes Frischplasma, quarantänegelagert und Methylenblau/Licht-behandeltes Frischplasma). Bundesgesundhbl 1997;8:307-9.
23. Walther-Wenke G, Dörner R, Montag-Lessing T, Lange H, Baumann B, Däubener W, et al. Working Party on "Microbiological investigations in transfusion medicine of the advisory board of the German ministry of health". Contamination rates of blood components in Germany. International Symposium of the Paul-Ehrlich-Institute and the University of Heidelberg. New aspects in microbial safety of blood components. Heidelberg 1999.
24. Walther-Wenke G, Pollmeier A, Horstmann E, Böcker W. Outcome quality in terms of product safety in preoperative autologous blood donation. Transfus Med Hemother 2004;31:214-20.
25. International Forum. Bacterial contamination of blood components. Vox Sang 2000;78:59-67.
26. Brecher ME, Hay SN, Rothenberg SJ. Monitoring of apheresis platelet bacterial contamination with an automated liquid culture system: a university experience. Transfusion 2003;43:974-8.
27. Macauley A, Chanraseker A, Gessis G, Morri KG, McClellan WM. Operational feasibility of routine bacterial monitoring of platelets. Transfus Med 2003;13:189-95.
28. Schelstraete B, Bignens G, Wuyts G. Prevalence of bacteria in leucodepleted pooled platelet concentrates and apheresis platelets: current status in the Flemish Blood Service [abstract]. Vox Sang 1999;78(Suppl 1):P373.
29. Wendel S, Fontao-Wendel R, Germano S, Morato LE, Lazar A, Sakashita A. Screening of bacterial contamination in a routine scale for blood components production in a Brazilian Blood Bank [abstract]. Vox Sang 1999;78(Suppl 1):P376.
30. International forum on evaluation of stored platelets. Vox Sang 2004;86:203-23.
31. Ness P, Hayden B, Kingk K, Barrasso C, Kickler T, Fuller A, et al. Single-donor platelets reduce the risk of septic platelet transfusion reactions. Transfusion 2001;41:857-61.
32. Wagner SJ, Robinette D, Friedmann LI, Miripol J. Diversion of initial blood flow to prevent whole-blood contamination by skin surface bacteria: an in vitro model. Transfusion 2000;40:335-8.
33. de Korte D, Marcelis JH, Verhoeven AJ, Soeterboek AM. Diversion of first blood volume results in a reduction of bacterial contamination of whole-blood collections. Vox Sang 2002;83:13-6.
34. Yedema T, Curvers J, de Korte W, Bos H. Reduction of incidence of bacterial contamination of thrombocyte concentrates [abstract 51A]. Transfusion 2003;43(Suppl. SP29).
35. McDonald CP, Roy A, Mahajan P, Smith R, Charlett A, Barbara JA. Relative values of the interventions of diversion and improved donor-arm disinfection to reduce the bacterial risk from blood transfusion. Vox Sang 2004;86:178-82.
36. McDonald CP, Lowe P, Roy A, Robbin S, Hartley S, Harrison JF, et al. Evaluation of donor arm disinfection techniques. Vox Sang 2001;80:135-41.
37. Brumit MC, Shauna N, Hay MT, Brecher ME. Bacteria detection. In: Brecher ME, editor. Bacterial and parasitic contamination of blood components. Bethesda, MD: AABB Press 2003:57-81.
38. Munksgaard L, Albjerg L, Lillevang ST, Gahn-Hansen B, Georgsen J. Detection of bacterial contamination of platelet components: six years' experience with the BacT/ ALERT system. Transfusion 2004;44:1166-73.
39. Larsen CP, Ezligini F, Hermansen NO, Kjeldsen-Kragli J. Six years' experience of using the BacT/ALERT system to screen all platelet concentrates, and additional testing of outdated platelet concentrates to estimate the frequency of false-negative results. Vox Sang 2005;88:93-7.
40. Fang CT, Chambers LA, Kennedy J, Strupp A, Fucci MCH, Janas JA, Tang Y, et al. Detection of bacterial contamination in apheresis platelet products: American Red Cross experience, 2004. Transfusion 2005;45:1845-52.
41. te Boekhorst PAW, Beckers EAM, Vos MC, Vermeij H, van Rhenen DJ. Clinical significance of bacteriologic screening in platelet concentrates. Transfusion 2005;45:514-9.
42. GERMS Group. False-positive alarms for bacterial screening of platet concentrates with BacT/ALERT new-generation plastic bottles: a multicenter pilot study. Transfusion 2005;45:1267-74.
43. Burkhart J, Wittmann G, Howe J, Michel P, Schramm W, Weinauer F. Klebsiella pneumoniae in platelet concentrates - a case report. Transfus Med Hemother 2005;32(Suppl 1):64 (P8.6).
44. Holme S, Bunch C, Selman B. Bacterial contamination in stored platelets: performance of the Pall eBDS system under routine use conditions. Vox Sang 2005;89(Suppl 1):P-194.
45. McDonald CP, Pearce S, Wilkins K, Colvin J, Robbins S, Colley L, et al. Pall eBDS: an enhanced bacterial detection system for screening platelet concentrates. Transfus Med 2005;15:259-68.
46. Schmidt M, Weis C, Heck J, Montag T, Nicol SB, Hourfar MK, et al. Optimized Scansystem™ platelet kit for bacterial detection with enhanced sensitivity: detection within 24 h after spiking. Vox Sang 2005;89:135-9.
47. McDonald CP, Colvin J, Robbins S, Barbara JAJ. Use of a solid-phase fluorescent cytometric technique for the detection of bacteria in platelet concentrates. Transfus Med 2005;15:175-83.
48. Mohammadi T, Pietersz RN, Vandenbroucke-Grauls CM, Savelkoul PH, Reesink HW. Detection of bacteria in platelet concentrates: comparison of broad-range real-time 16S rDNA PCR and automated culturing. Transfusion 2005;45:731-6.
49. Mohammadi T, Pietersz RN, Scholtalbers LA, Vandenbroucke-Grauls CM, Savelkoul PH, Reesink HW. Optimal sampling time after preparation of platelet concentrates for detection of bacterial contamination by quantitative real-time polymerase chain reaction. Vox Sang 2005;89: 208-14.