Sialic acids and heparan sulfate proteoglycans are mechanosensory components of the endothelial cell glycocalyx

Proceedings of the 2005 Summer Bioengineering Conference

Volumn 2005, Issue , 2005, Pages 137-138

  Pahakis, Manolis Y ^a   Kosky, Jason R ^b   Dull, Randal O ^c   Tarbell, John M ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33646559552     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (5)

1. Davies, P. F., 1995, "Flow-mediated endothelial mechanotransduction, '" Phys. Rev., 75 (3):519-560.
2. Florian, J. A., Kosky J. R., Ainslie K., Pang Z., Dull R.O., and Tarbell J. M., 2003, "Heparan sulfate proteoglycan is a mechanosensor on endothelial cells," Circ. Res., 93:e136-e142.
3. Thi, M. M., Tarbell, J. M., Weinbaum, S., and Spray, D. C., 2004, "The role of the glycocalyx in reorganization of the actin cytoskeleton under fluid shear stress: a "bumper-car'' model," Proc. Natl. Acad. Sci., 101 (47): 16483-88.
4. Ponik, S. M., and Pavalko, F. M., 2004, "Formation of focal adhesions on fibronectin promotes fluid shear stress induction of COX-2 and PGE2 release in MC3T3-E1 osteoblasts," J. Appl. Physiol., 97 (1): 135-142.
5. Sill, H. W., Chang, Y. S., Artman, J. R., Frangos, J. A., Hollis T. M., and Tarbell, J. M., 1992, "Shear stress increases hydraulic conductivity of cultured endothelial monolayers," Am. J. Physiol., 268:H535-H543.