Targeting Retroviral Zn Finger-DNA Interactions: A Small-Molecule Approach Using the Electrophilic Nature of trans-Platinum-Nucleobase Compounds

Chemistry and Biology

Volumn 13, Issue 5, 2006, Pages 539-548

  Anzellotti, Atilio I ^a   Liu, Qin ^a   Bloemink, Marieke J ^a   Scarsdale, J Neel ^a   Farrell, Nicholas ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

CHEMBIO

Indexed keywords

CAPSID PROTEIN; DNA; GAG PROTEIN; NCP7 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; PLATINUM; VIRUS PROTEIN; ZINC FINGER PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; DRUG DESIGN; ELECTROSPRAY MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; SPECTROFLUOROMETRY;

AMINO ACID SEQUENCE; CAPSID PROTEINS; DNA; DRUG DESIGN; GENE PRODUCTS, GAG; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLATINUM; PROTEIN BINDING; SPECTROMETRY, FLUORESCENCE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; VIRAL PROTEINS; ZINC FINGERS;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 33646550188     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2006.04.004     Document Type: Article

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