메뉴 건너뛰기




Volumn 37, Issue 3, 2006, Pages 359-368

Role of intestinal epithelial cells in the innate immune defence of the pig intestine

Author keywords

Epithelial intestinal cells; Innate immune defence; Pig

Indexed keywords

CHEMOKINE; CYTOKINE; DEFENSIN; POLYPEPTIDE ANTIBIOTIC AGENT; TOXIC SUBSTANCE;

EID: 33646537840     PISSN: 09284249     EISSN: 12979716     Source Type: Journal    
DOI: 10.1051/vetres:2006006     Document Type: Review
Times cited : (141)

References (79)
  • 1
    • 0036346860 scopus 로고    scopus 로고
    • Response of intestinal epithelial cells to Trichuris suis excretory-secretory products and the influence on Campylobacter jejuni invasion under in vitro conditions
    • Abner S.R., Hill D.E., Turner J.R., Black E.D., Bartlett P., Urban J.F., Mansfield L.S., Response of intestinal epithelial cells to Trichuris suis excretory-secretory products and the influence on Campylobacter jejuni invasion under in vitro conditions, J. Parasitol. 88 (2002) 738-745.
    • (2002) J. Parasitol. , vol.88 , pp. 738-745
    • Abner, S.R.1    Hill, D.E.2    Turner, J.R.3    Black, E.D.4    Bartlett, P.5    Urban, J.F.6    Mansfield, L.S.7
  • 2
    • 0026349223 scopus 로고
    • Amino acid sequence of PR-39. Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides
    • Agerberth B., Lee J., Bergman T., Carlquist M., Boman H.G., Mutt V., Jörnvall H., Amino acid sequence of PR-39. Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides, Eur. J. Biochem. 202 (1991) 849-854.
    • (1991) Eur. J. Biochem. , vol.202 , pp. 849-854
    • Agerberth, B.1    Lee, J.2    Bergman, T.3    Carlquist, M.4    Boman, H.G.5    Mutt, V.6    Jörnvall, H.7
  • 5
    • 0030611762 scopus 로고    scopus 로고
    • Prostaglandins I2 and E2 have a synergistic role in rescuing epithelial barrier function in porcine ileum
    • Blikslager A.T., Roberts M.C., Rhoads J.M., Argenzio R.A., Prostaglandins I2 and E2 have a synergistic role in rescuing epithelial barrier function in porcine ileum, J. Clin. Invest. 100 (1997) 1928-1933.
    • (1997) J. Clin. Invest. , vol.100 , pp. 1928-1933
    • Blikslager, A.T.1    Roberts, M.C.2    Rhoads, J.M.3    Argenzio, R.A.4
  • 6
    • 24944587966 scopus 로고    scopus 로고
    • The effects of mycotoxins, fungal food contaminants, on the intestinal epithelial cell derived innate immune response
    • Bouhet S., Oswald I.P., The effects of mycotoxins, fungal food contaminants, on the intestinal epithelial cell derived innate immune response, Vet. Immunol. Immunopathol. 108 (2005) 199-209.
    • (2005) Vet. Immunol. Immunopathol. , vol.108 , pp. 199-209
    • Bouhet, S.1    Oswald, I.P.2
  • 8
    • 0034665313 scopus 로고    scopus 로고
    • An intra-Peyer's patch gene transfer model for studying mucosal tolerance: Distinct roles of B7 and IL-12 in mucosal T cell tolerance
    • Chen Y., Song K., Eck S.L., An intra-Peyer's patch gene transfer model for studying mucosal tolerance: distinct roles of B7 and IL-12 in mucosal T cell tolerance, J. Immunol. 165 (2000) 3145-3153.
    • (2000) J. Immunol. , vol.165 , pp. 3145-3153
    • Chen, Y.1    Song, K.2    Eck, S.L.3
  • 10
    • 0034994474 scopus 로고    scopus 로고
    • Microbial modulation of innate defense: Goblet cells and the intestinal mucus layer
    • Deplanke B., Gaskins H.R., Microbial modulation of innate defense: goblet cells and the intestinal mucus layer, Am. J. Clin. Nutr. 73 (2001) 1131S-1141S.
    • (2001) Am. J. Clin. Nutr. , vol.73
    • Deplanke, B.1    Gaskins, H.R.2
  • 13
    • 0037782141 scopus 로고    scopus 로고
    • Immunobiology of epithelial chemokines in the intestinal mucosa
    • Dwinell M.B., Johanesen P.A., Smith J.M., Immunobiology of epithelial chemokines in the intestinal mucosa, Surgery 133 (2003) 601-607.
    • (2003) Surgery , vol.133 , pp. 601-607
    • Dwinell, M.B.1    Johanesen, P.A.2    Smith, J.M.3
  • 14
    • 0031455380 scopus 로고    scopus 로고
    • The complete cDNA sequence and structural polymorphism of the polypeptide chain of porcine submaxillary mucin
    • Eckhardt A.E., Timpte C.S., DeLuca A.W., Hill R.L., The complete cDNA sequence and structural polymorphism of the polypeptide chain of porcine submaxillary mucin, J. Biol. Chem. 272 (1997) 33204-33210.
    • (1997) J. Biol. Chem. , vol.272 , pp. 33204-33210
    • Eckhardt, A.E.1    Timpte, C.S.2    DeLuca, A.W.3    Hill, R.L.4
  • 15
    • 0034952982 scopus 로고    scopus 로고
    • Defensins - Innate immunity at the epithelial frontier
    • Fellermann K., Stange E.F., Defensins - innate immunity at the epithelial frontier, Eur. J. Gastroenterol. Hepatol. 13 (2001) 771-776.
    • (2001) Eur. J. Gastroenterol. Hepatol. , vol.13 , pp. 771-776
    • Fellermann, K.1    Stange, E.F.2
  • 17
    • 0035083020 scopus 로고    scopus 로고
    • Bacterially induced activation of interleukin-18 in porcine intestinal mucosa
    • Foss D.L., Zilliox M.J., Murtaugh M.P., Bacterially induced activation of interleukin-18 in porcine intestinal mucosa, Vet. Immunol. Immunopathol. 78 (2001) 263-277.
    • (2001) Vet. Immunol. Immunopathol. , vol.78 , pp. 263-277
    • Foss, D.L.1    Zilliox, M.J.2    Murtaugh, M.P.3
  • 20
    • 0028092047 scopus 로고
    • Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds
    • USA
    • Gallo R.L., Ono M., Povsic T., Page C., Eriksson E., Klagsbrun M., Bernfield M., Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds, Proc. Natl. Acad. Sci. USA 91 (1994) 11035-11039.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 11035-11039
    • Gallo, R.L.1    Ono, M.2    Povsic, T.3    Page, C.4    Eriksson, E.5    Klagsbrun, M.6    Bernfield, M.7
  • 23
    • 0027715358 scopus 로고
    • Breaking through the tight junction barrier
    • Gumbiner B.M., Breaking through the tight junction barrier, J. Cell Biol. 123 (1993) 1631-1633.
    • (1993) J. Cell Biol. , vol.123 , pp. 1631-1633
    • Gumbiner, B.M.1
  • 24
    • 0030056968 scopus 로고    scopus 로고
    • Cell adhesion: The molecular basis of tissue architecture and morphogenesis
    • Gumbiner B.M., Cell adhesion: the molecular basis of tissue architecture and morphogenesis, Cell 84 (1996) 345-357.
    • (1996) Cell , vol.84 , pp. 345-357
    • Gumbiner, B.M.1
  • 25
    • 0027830396 scopus 로고
    • Epithelial properties of human intestinal Caco-2 cells cultured in a serum-free medium
    • Hashimoto K., Shimizu M., Epithelial properties of human intestinal Caco-2 cells cultured in a serum-free medium, Cytotechnology 13 (1993) 175-184.
    • (1993) Cytotechnology , vol.13 , pp. 175-184
    • Hashimoto, K.1    Shimizu, M.2
  • 26
    • 0037340434 scopus 로고    scopus 로고
    • Angiogenins: A new class of microbicidal proteins involved in innate immunity
    • Hooper L.V., Stappenbeck T.S., Hong C.V., Gordon J.I., Angiogenins: a new class of microbicidal proteins involved in innate immunity, Nat. Immunol. 4 (2003) 269-273.
    • (2003) Nat. Immunol. , vol.4 , pp. 269-273
    • Hooper, L.V.1    Stappenbeck, T.S.2    Hong, C.V.3    Gordon, J.I.4
  • 27
    • 0030976983 scopus 로고    scopus 로고
    • Chemoattractant properties of PR-39, a neutrophil antibacterial peptide
    • Huang H., Ross C.R., Blecha F., Chemoattractant properties of PR-39, a neutrophil antibacterial peptide, J. Leukoc. Biol. 61 (1997) 624-629.
    • (1997) J. Leukoc. Biol. , vol.61 , pp. 624-629
    • Huang, H.1    Ross, C.R.2    Blecha, F.3
  • 28
    • 0028864991 scopus 로고
    • A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
    • Jung H.C., Eckmann L., Yang S.K., Panja A., Fierer J., Morzycka-Wroblewska E., Kagnoff M.F., A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion, J. Clin. Invest. 95 (1995) 55-65.
    • (1995) J. Clin. Invest. , vol.95 , pp. 55-65
    • Jung, H.C.1    Eckmann, L.2    Yang, S.K.3    Panja, A.4    Fierer, J.5    Morzycka-Wroblewska, E.6    Kagnoff, M.F.7
  • 29
    • 0027365632 scopus 로고
    • Epithelioid and fibroblastic cell lines derived from the ileum of an adult histocompatible miniature boar (d/d haplotype) and immortalized by SV40 plasmid
    • Kaeffer B., Bottreau E., Velge P., Pardon P., Epithelioid and fibroblastic cell lines derived from the ileum of an adult histocompatible miniature boar (d/d haplotype) and immortalized by SV40 plasmid, Eur. J. Cell. Biol. 62 (1993) 152-162.
    • (1993) Eur. J. Cell. Biol. , vol.62 , pp. 152-162
    • Kaeffer, B.1    Bottreau, E.2    Velge, P.3    Pardon, P.4
  • 32
    • 0001600916 scopus 로고    scopus 로고
    • The high water-holding capacity of pea inner fibers affects the ileal flow of endogenous amino acids in pigs
    • Leterme P., Froidmont E., Rossi F., Théwis E., The high water-holding capacity of pea inner fibers affects the ileal flow of endogenous amino acids in pigs, J. Agric. Food Chem. 46 (1998) 1927-1934.
    • (1998) J. Agric. Food Chem. , vol.46 , pp. 1927-1934
    • Leterme, P.1    Froidmont, E.2    Rossi, F.3    Théwis, E.4
  • 33
    • 0029074142 scopus 로고
    • Modulation of epithelial permeability by extracellular macromolecules
    • Lewis S.A., Berg J.R., Kleine T.J., Modulation of epithelial permeability by extracellular macromolecules, Physiol. Rev. 75 (1995) 561-589.
    • (1995) Physiol. Rev. , vol.75 , pp. 561-589
    • Lewis, S.A.1    Berg, J.R.2    Kleine, T.J.3
  • 34
    • 0035614026 scopus 로고    scopus 로고
    • Dietary influence on the secretion into and degranulation of mucins in the digestive tract of monogastric and humans
    • Lien K.A., Sauer W.C., He J.M., Dietary influence on the secretion into and degranulation of mucins in the digestive tract of monogastric and humans, J. Anim. Feed Sci. 10 (2001) 223-245.
    • (2001) J. Anim. Feed Sci. , vol.10 , pp. 223-245
    • Lien, K.A.1    Sauer, W.C.2    He, J.M.3
  • 36
    • 0029081456 scopus 로고
    • Endogenous amino nitrogen collected from pigs with end-to-end ileorectal anastomosis is affected by the method of estimation and altered by dietary fiber
    • Mariscal-Landin G., Seve B., Colleaux Y., Lebreton Y., Endogenous amino nitrogen collected from pigs with end-to-end ileorectal anastomosis is affected by the method of estimation and altered by dietary fiber, J. Nutr. 125 (1995) 136-146.
    • (1995) J. Nutr. , vol.125 , pp. 136-146
    • Mariscal-Landin, G.1    Seve, B.2    Colleaux, Y.3    Lebreton, Y.4
  • 37
    • 0028793208 scopus 로고
    • Diet-dependent and diet-independent metabolic responses underlie growth stasis of pigs at weaning
    • McCracken B.A., Gaskins H.R., Ruwe-Kaiser P.J., Klasing K.C., Jewell D.E., Diet-dependent and diet-independent metabolic responses underlie growth stasis of pigs at weaning, J. Nutr. 125 (1995) 2838-2845.
    • (1995) J. Nutr. , vol.125 , pp. 2838-2845
    • McCracken, B.A.1    Gaskins, H.R.2    Ruwe-Kaiser, P.J.3    Klasing, K.C.4    Jewell, D.E.5
  • 38
    • 0033052237 scopus 로고    scopus 로고
    • Weaning anorexia may contribute to local inflammation in the piglet small intestine
    • McCracken B.A., Spurlock M.E., Roos M.A., Zuckermann F.A., Gaskins H.R., Weaning anorexia may contribute to local inflammation in the piglet small intestine, J. Nutr. 129 (1999) 613-619.
    • (1999) J. Nutr. , vol.129 , pp. 613-619
    • McCracken, B.A.1    Spurlock, M.E.2    Roos, M.A.3    Zuckermann, F.A.4    Gaskins, H.R.5
  • 39
    • 0029936599 scopus 로고    scopus 로고
    • The effect of cytokine stimulation on IL-1 receptor mRNA expression by intestinal epithelial cells
    • McGee D.W., Vitkus S.J., Lee P., The effect of cytokine stimulation on IL-1 receptor mRNA expression by intestinal epithelial cells, Cell. Immunol. 168 (1996) 276-280.
    • (1996) Cell. Immunol. , vol.168 , pp. 276-280
    • McGee, D.W.1    Vitkus, S.J.2    Lee, P.3
  • 40
    • 14144254193 scopus 로고    scopus 로고
    • Transient changes of transforming growth factor-beta expression in the small intestine of the pig in association with weaning
    • Mei J., Xu R.J., Transient changes of transforming growth factor-beta expression in the small intestine of the pig in association with weaning, Br. J. Nutr. 93 (2005) 37-45.
    • (2005) Br. J. Nutr. , vol.93 , pp. 37-45
    • Mei, J.1    Xu, R.J.2
  • 41
    • 0023112602 scopus 로고
    • Gastrointestinal mucus, a medium for survival and for elimination of parasitic nematodes and protozoa
    • Miller H.R.P., Gastrointestinal mucus, a medium for survival and for elimination of parasitic nematodes and protozoa, Parasitology 94 (1987) S77-S100.
    • (1987) Parasitology , vol.94
    • Miller, H.R.P.1
  • 42
    • 16544369329 scopus 로고    scopus 로고
    • Neutrophil and small intestinal lymphocyte migration after Salmonella typhimurium infection: Impact of fermentable fiber
    • Milo L.A., Correa-Matos N.J., Donovan S.M., Tappenden K.A., Neutrophil and small intestinal lymphocyte migration after Salmonella typhimurium infection: impact of fermentable fiber, J. Pediatr. Gastroenterol. Nutr. 39 (2004) 73-79.
    • (2004) J. Pediatr. Gastroenterol. Nutr. , vol.39 , pp. 73-79
    • Milo, L.A.1    Correa-Matos, N.J.2    Donovan, S.M.3    Tappenden, K.A.4
  • 43
    • 0037810388 scopus 로고    scopus 로고
    • A review of interactions between dietary fibre and the intestinal mucosa, and their consequences on digestive health in young nonruminant animals
    • Montagne L., Pluske J.R., Hampson D.J., A review of interactions between dietary fibre and the intestinal mucosa, and their consequences on digestive health in young nonruminant animals, Anim. Feed Sci. Technol. 108 (2003) 934-943.
    • (2003) Anim. Feed Sci. Technol. , vol.108 , pp. 934-943
    • Montagne, L.1    Pluske, J.R.2    Hampson, D.J.3
  • 44
    • 1842420528 scopus 로고    scopus 로고
    • Effect of diet on mucin kinetics and composition: Nutrition and health implications
    • Montagne L., Piel C., Lalles J.P., Effect of diet on mucin kinetics and composition: nutrition and health implications, Nutr. Rev. 62 (2004) 105-114.
    • (2004) Nutr. Rev. , vol.62 , pp. 105-114
    • Montagne, L.1    Piel, C.2    Lalles, J.P.3
  • 47
    • 0036089285 scopus 로고    scopus 로고
    • Inflammatory cytokines and antigen presenting cell activation
    • Murtaugh M.P., Foss D.L., Inflammatory cytokines and antigen presenting cell activation, Vet. Immunol. Immunopathol. 87 (2002) 109-121.
    • (2002) Vet. Immunol. Immunopathol. , vol.87 , pp. 109-121
    • Murtaugh, M.P.1    Foss, D.L.2
  • 48
    • 0030000550 scopus 로고    scopus 로고
    • Antigen sampling across epithelial barriers and induction of mucosal immune responses
    • Neutra M.R., Pringault E., Kraehenbuhl J.P., Antigen sampling across epithelial barriers and induction of mucosal immune responses, Annu. Rev. Immunol. 14 (1996) 275-300.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 275-300
    • Neutra, M.R.1    Pringault, E.2    Kraehenbuhl, J.P.3
  • 49
    • 16244375554 scopus 로고    scopus 로고
    • Development of a porcine small intestinal cDNA micro-array: Characterization and functional analysis of the response to enterotoxigenic E. coli
    • Niewold T.A., Kerstens H.H., van der Meulen J., Smits M.A., Hulst M.M., Development of a porcine small intestinal cDNA micro-array: characterization and functional analysis of the response to enterotoxigenic E. coli, Vet. Immunol. Immunopathol. 105 (2005) 317-329.
    • (2005) Vet. Immunol. Immunopathol. , vol.105 , pp. 317-329
    • Niewold, T.A.1    Kerstens, H.H.2    Van Der Meulen, J.3    Smits, M.A.4    Hulst, M.M.5
  • 50
    • 0013455639 scopus 로고
    • Significance of endogenous gut nitrogen losses in the nutrition of growing pig: A review
    • Nyachoti C.M., De Lange C.F., MacBride B.W., Schulze H., Significance of endogenous gut nitrogen losses in the nutrition of growing pig: a review, Can. J. Anim. Sci. 77 (1977) 149-163.
    • (1977) Can. J. Anim. Sci. , vol.77 , pp. 149-163
    • Nyachoti, C.M.1    De Lange, C.F.2    MacBride, B.W.3    Schulze, H.4
  • 52
    • 0033527547 scopus 로고    scopus 로고
    • The structure and assembly of secreted mucins
    • Perez-Vilar J., Hill R.L., The structure and assembly of secreted mucins, J. Biol. Chem. 274 (1999) 31751-31754.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31751-31754
    • Perez-Vilar, J.1    Hill, R.L.2
  • 53
    • 0142122335 scopus 로고    scopus 로고
    • Effects of Oesophagostomum dentatum and dietary carbohydrates on morphology of the large intestine of pigs
    • Petkevicius S., Bach Knudsen K.E., Murrell K.D., Effects of Oesophagostomum dentatum and dietary carbohydrates on morphology of the large intestine of pigs, Vet. Parasitol. 116 (2003) 125-138.
    • (2003) Vet. Parasitol. , vol.116 , pp. 125-138
    • Petkevicius, S.1    Bach Knudsen, K.E.2    Murrell, K.D.3
  • 54
    • 1542376906 scopus 로고    scopus 로고
    • Weaning is associated with an upregulation of expression of inflammatory cytokines in the intestine of piglets
    • Pié S., Lalles J.P., Blazy F., Laffitte J., Seve B., Oswald I.P., Weaning is associated with an upregulation of expression of inflammatory cytokines in the intestine of piglets, J. Nutr. 134 (2004) 641-647.
    • (2004) J. Nutr. , vol.134 , pp. 641-647
    • Pié, S.1    Lalles, J.P.2    Blazy, F.3    Laffitte, J.4    Seve, B.5    Oswald, I.P.6
  • 55
    • 10244250303 scopus 로고    scopus 로고
    • Estimation of ileal output of gastro-intestinal glycoprotein in weaned piglets using three different methods
    • Piel C., Montagne L., Salgado P., Lalles J.P., Estimation of ileal output of gastro-intestinal glycoprotein in weaned piglets using three different methods, Reprod. Nutr. Dev. 44 (2004) 419-435.
    • (2004) Reprod. Nutr. Dev. , vol.44 , pp. 419-435
    • Piel, C.1    Montagne, L.2    Salgado, P.3    Lalles, J.P.4
  • 56
    • 0033669635 scopus 로고    scopus 로고
    • First line of defense: The role of the intestinal epithelium as an active component of the mucosal immune system
    • Pitman R.S., Blumberg R.S., First line of defense: the role of the intestinal epithelium as an active component of the mucosal immune system, J. Gastroenterol. 35 (2000) 805-814.
    • (2000) J. Gastroenterol. , vol.35 , pp. 805-814
    • Pitman, R.S.1    Blumberg, R.S.2
  • 58
    • 0029018711 scopus 로고
    • Local stimulatory effect of short chain fatty acids on the mucus release from the hindgut mucosa of rats (Rattus norvegicus)
    • Sakata T., Setoyama H., Local stimulatory effect of short chain fatty acids on the mucus release from the hindgut mucosa of rats (Rattus norvegicus), Comp. Biochem. Phys. A 111 (1995) 429-432.
    • (1995) Comp. Biochem. Phys. A , vol.111 , pp. 429-432
    • Sakata, T.1    Setoyama, H.2
  • 59
    • 0031938678 scopus 로고    scopus 로고
    • Cell adhesion and migration. IV. Lymphocyte trafficking in the intestine and liver
    • Salmi M., Adams D., Jalkanen S., Cell adhesion and migration. IV. Lymphocyte trafficking in the intestine and liver, Am. J. Physiol. 274 (1998) G1-G6.
    • (1998) Am. J. Physiol. , vol.274
    • Salmi, M.1    Adams, D.2    Jalkanen, S.3
  • 60
    • 10244226689 scopus 로고    scopus 로고
    • War and peace at mucosal surfaces
    • Sansonetti P.J., War and peace at mucosal surfaces, Nat. Rev. Immunol. 4 (2004) 953-964.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 953-964
    • Sansonetti, P.J.1
  • 61
    • 0032693636 scopus 로고    scopus 로고
    • Functional and structural comparison of cytokines in different species
    • Scheerlinck J.P., Functional and structural comparison of cytokines in different species, Vet. Immunol. Immunopathol. 72 (1999) 39-44.
    • (1999) Vet. Immunol. Immunopathol. , vol.72 , pp. 39-44
    • Scheerlinck, J.P.1
  • 62
    • 0034960427 scopus 로고    scopus 로고
    • The role of epithelial cells in immune regulation in the gut
    • Shao L., Serrano D., Mayer L., The role of epithelial cells in immune regulation in the gut, Semin. Immunol. 13 (2001) 163-176.
    • (2001) Semin. Immunol. , vol.13 , pp. 163-176
    • Shao, L.1    Serrano, D.2    Mayer, L.3
  • 63
    • 0029664907 scopus 로고    scopus 로고
    • PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47phox
    • USA
    • Shi J., Ross C.R., Leto T.L., Blecha F., PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47phox, Proc. Natl. Acad. Sci. USA 93 (1996) 6014-6018.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 6014-6018
    • Shi, J.1    Ross, C.R.2    Leto, T.L.3    Blecha, F.4
  • 64
    • 0033023402 scopus 로고    scopus 로고
    • Porcine epithelial β-defensin-1 is expressed in the dorsal tongue at antimicrobial concentrations
    • Shi J., Zhang G., Wu H., Ross C.R., Blecha F., Ganz T., Porcine epithelial β-defensin-1 is expressed in the dorsal tongue at antimicrobial concentrations, Infect. Immun. 67 (1999) 3121-3127.
    • (1999) Infect. Immun. , vol.67 , pp. 3121-3127
    • Shi, J.1    Zhang, G.2    Wu, H.3    Ross, C.R.4    Blecha, F.5    Ganz, T.6
  • 65
    • 0036303112 scopus 로고    scopus 로고
    • Intestinal epithelial cells as a source of inflammatory cytokines and chemokines
    • Stadnyk A.W., Intestinal epithelial cells as a source of inflammatory cytokines and chemokines, Can. J. Gastroenterol. 16 (2002) 241-246.
    • (2002) Can. J. Gastroenterol. , vol.16 , pp. 241-246
    • Stadnyk, A.W.1
  • 67
    • 0036258290 scopus 로고    scopus 로고
    • Early cytokine response of gnotobiotic piglets to Salmonella enterica serotype typhimurium
    • Splichal I., Trebichavsky I., Muneta Y., Mori Y., Early cytokine response of gnotobiotic piglets to Salmonella enterica serotype typhimurium, Vet. Res. 33 (2002) 291-297.
    • (2002) Vet. Res. , vol.33 , pp. 291-297
    • Splichal, I.1    Trebichavsky, I.2    Muneta, Y.3    Mori, Y.4
  • 68
    • 0028009472 scopus 로고
    • Chemical synthesis and biological activity of a novel antibacterial peptide deduced from a pig myeloid cDNA
    • Storici P., Scocchi M., Tossi A., Gennaro R., Zanetti M., Chemical synthesis and biological activity of a novel antibacterial peptide deduced from a pig myeloid cDNA, FEBS Lett. 337 (1994) 303-307.
    • (1994) FEBS Lett. , vol.337 , pp. 303-307
    • Storici, P.1    Scocchi, M.2    Tossi, A.3    Gennaro, R.4    Zanetti, M.5
  • 71
    • 0347419126 scopus 로고    scopus 로고
    • Stimulation of butyrate production in the large intestine of weaning piglets by dietary fructooligosaccharides and its influence on the histological variables of the large intestinal mucosa
    • Tsukahara T., Iwasaki Y., Nakayama K., Ushida K., Stimulation of butyrate production in the large intestine of weaning piglets by dietary fructooligosaccharides and its influence on the histological variables of the large intestinal mucosa, J. Nutr. Sci. Vitaminol. 49 (2003) 414-421.
    • (2003) J. Nutr. Sci. Vitaminol. , vol.49 , pp. 414-421
    • Tsukahara, T.1    Iwasaki, Y.2    Nakayama, K.3    Ushida, K.4
  • 72
    • 0027157352 scopus 로고
    • Age and diet affect the composition of porcine colonic mucins
    • Turck D., Feste A., Lifschitz C.H., Age and diet affect the composition of porcine colonic mucins, Pediatr. Res. 33 (1993) 564-567.
    • (1993) Pediatr. Res. , vol.33 , pp. 564-567
    • Turck, D.1    Feste, A.2    Lifschitz, C.H.3
  • 74
    • 0036606951 scopus 로고    scopus 로고
    • Mammalian defensins in immunity: More than just microbicidal
    • Yang D., Biragyn A., Kwak L.W., Oppenheim J.J., Mammalian defensins in immunity: more than just microbicidal, Trends Immunol. 23 (2002) 291-296.
    • (2002) Trends Immunol. , vol.23 , pp. 291-296
    • Yang, D.1    Biragyn, A.2    Kwak, L.W.3    Oppenheim, J.J.4
  • 75
    • 0842326097 scopus 로고    scopus 로고
    • Cathelicidins, multifunctional peptides of the innate immunity
    • Zanetti M., Cathelicidins, multifunctional peptides of the innate immunity, J. Leukoc. Biol. 75 (2004) 39-48.
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 39-48
    • Zanetti, M.1
  • 76
  • 77
    • 0032489350 scopus 로고    scopus 로고
    • Molecular cloning and tissue expression of pBD-1, a porcine β-defensin
    • Zhang G., Wu H., Shi J., Ganz T., Ross C.R., Blecha F., Molecular cloning and tissue expression of pBD-1, a porcine β-defensin, FEBS Lett. 424 (1998) 37-40.
    • (1998) FEBS Lett. , vol.424 , pp. 37-40
    • Zhang, G.1    Wu, H.2    Shi, J.3    Ganz, T.4    Ross, C.R.5    Blecha, F.6
  • 78
    • 0033588381 scopus 로고    scopus 로고
    • Cloning and characterization of the gene for a new epithelial β-defensin: Genomic structure, chromosomal localization, and evidence for its constitutive expression
    • Zhang G., Hiraiwa H., Yasue H., Wu H., Ross C.R., Troyer D., Blecha F., Cloning and characterization of the gene for a new epithelial β-defensin: genomic structure, chromosomal localization, and evidence for its constitutive expression, J. Biol. Chem. 274 (1999) 24031-24037.
    • (1999) J. Biol. Chem. , vol.274 , pp. 24031-24037
    • Zhang, G.1    Hiraiwa, H.2    Yasue, H.3    Wu, H.4    Ross, C.R.5    Troyer, D.6    Blecha, F.7
  • 79
    • 0034184327 scopus 로고    scopus 로고
    • Porcine antimicrobial peptides: New prospects for ancient molecules of host defense
    • Zhang G., Ross C.R., Blecha F., Porcine antimicrobial peptides: new prospects for ancient molecules of host defense, Vet. Res. 31 (2000) 277-296.
    • (2000) Vet. Res. , vol.31 , pp. 277-296
    • Zhang, G.1    Ross, C.R.2    Blecha, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.