Synthesis and receptor binding evaluation of clavizepine analogues with no ring D substituents

Journal of Organic Chemistry

Volumn 71, Issue 10, 2006, Pages 3963-3966

  De La Fuente, M Carmen ^a   Pullan, Shirley E ^b   Biesmans, Ilse ^b   Domínguez, Domingo ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Psychiatry Division   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING EVALUATION; CLAVIZEPINE; ELECTROPHILIC CYCLIZATION; SULFONAMIDE ACETALS;

ASSAYS; ETHERS; REACTION KINETICS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

NITROGEN COMPOUNDS;

2,12B DIHYDRO 2,3,4,12B TETRAHYDRO 1H XANTHENO[9,1 CD]AZEPINE; 4 HYDROXY 2,3,4,12B TETRAHYDRO 1H XANTHENO[9,1 CD]AZEPINE; ADRENERGIC RECEPTOR; AZEPINE DERIVATIVE; CLAVIZEPINE; CLAVIZEPINE DERIVATIVE; DOPAMINE RECEPTOR; NATURAL PRODUCT; SEROTONIN RECEPTOR; UNCLASSIFIED DRUG; XANTHENO[9,1 CD]AZEPINE;

ARTICLE; BINDING ASSAY; CYCLIZATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; MITSUNOBU REACTION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

AZEPINES; FUMARIACEAE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING; RECEPTORS, SEROTONIN; XANTHENES;

EID: 33646534197     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo052320c     Document Type: Article

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