Rotating methadone to other opioids: A lesson in the mechanisms of opioid tolerance and opioid-induced pain

Journal of Palliative Medicine

Volumn 9, Issue 2, 2006, Pages 488-493

  Prommer, Eric ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; CALCITONIN; CORTICOSTEROID; FENTANYL; GABAPENTIN; GEFITINIB; HYDROMORPHONE; METHADONE; MORPHINE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PAMIDRONIC ACID;

ADULT; ANALGESIA; ARTICLE; BONE PAIN; CASE REPORT; DRUG TOLERANCE; DYSPHORIA; HUMAN; LUNG NON SMALL CELL CANCER; MALE; PARESTHESIA; SOMNOLENCE;

ADULT; DRUG TOLERANCE; HUMANS; HYPERALGESIA; MALE; METHADONE; NARCOTICS; PAIN; RECEPTORS, N-METHYL-D-ASPARTATE; UNITED STATES;

EID: 33646532430     PISSN: 10966218     EISSN: None     Source Type: Journal    
DOI: 10.1089/jpm.2006.9.488     Document Type: Article

References (24)

1. Moryl N, Santiago-Palma J, Kornick C, Derby S, Fischberg D, Payne R, Manfredi PL: Pitfalls of opioid rotation: Substituting another opioid for methadone in patients with cancer pain. Pain 2002;96:325-328.
2. Manfredi PL, Gonzales GR, Cheville AL, Kornick C, Payne R: Methadone analgesia in cancer pain patients on chronic methadone maintenance therapy. J Pain Symptom Manage 2001;21:169-174.
3. Vigano A, Fan D, Bruera E: Individualized use of methadone and opioid rotation in the comprehensive management of cancer pain associated with poor prognostic indicators. Pain 1996;67:115-119.
4. Arner S, Meyerson BA: Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain. Pain 1988;33:11-23.
5. Mao J, Price DD, Mayer DJ: Mechanisms of hyperalgesia and morphine tolerance: A current view of their possible interactions. Pain 1995;62:259-274.
6. Dickenson AH, Sullivan AF: Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the rat. Brain Res 1990;506:31-39.
7. Mercadante S, Portenoy RK: Opioid poorly-responsive cancer pain. Part 1: Clinical considerations. J Pain Symptom Manage 2001;21:144-150.
8. Medhurst SJ, Walker K, Bowes M, Kidd BL, Glatt M, Muller M, Haltenberger M, Vaxelaire J, O'Reilly T, Wotherspoon G, Winter J, Green J, Urban L: A rat model of bone cancer pain. Pain 2002;96:129-140.
9. Stevens CW, Yaksh TL: Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion. J Pharmacol Exp Ther 1989;250;1-8.
10. Morley JS, Watt JW, Wells JC, Miles JB, Finnegan MJ, Leng G: Methadone in pain uncontrolled by morphine. Lancet 1993;342:1243.
11. Fitzgibbon DR, Ready LB: Intravenous high-dose methadone administered by patient controlled analgesia and continuous infusion for the treatment of cancer pain refractory to high-dose morphine. Pain 1997;73:259-261.
12. Mercadante S, Ferrera P, Villari P, Arcuri E: Hyperalgesia: An emerging iatrogenic syndrome. J Pain Symptom Manage 2003;26:769-775.
13. Simonnet G, Rivat C: Opioid-induced hyperalgesia: Abnormal or normal pain? Neuroreport 2003;14:1-7.
14. Mao J, Price DD, Mayer DJ: Thermal hyperalgesia in association with the development of morphine tolerance in rats: Roles of excitatory amino acid receptors and protein kinase C. J Neurosci 1994;14:2301-2312.
15. Mao J: NMDA and opioid receptors: Their interactions in antinociception, tolerance and neuroplasticity. Brain Res Brain Res Rev 1999;30:289-304.
16. 2+ in mammalian neurons. Trends Pharmacol Sci 1990;11:254-260.
17. Schoepp DD, Conn PJ: Metabotropic glutamate receptors in brain function and pathology. Trends Pharmacol Sci 1993;14:13-20.
18. Haley JE, Dickenson AH, Schachter M: Electrophysiological evidence for a role of nitric oxide in prolonged chemical nociception in the rat. Neuropharmacology 1992;31:251-258.
19. Meller ST, Pechman PS, Gebhart GF, Maves TJ: Nitric oxide mediates the thermal hyperalgesia produced in a model of neuropathic pain in the rat. Neuroscience 1992;50:7-10.
20. Mao J, Mayer DJ, Hayes RL, Price DD: Spatial patterns of increased spinal cord membrane-bound protein kinase C and their relation to increases in 14C-2-deoxyglucose metabolic activity in rats with painful peripheral mononeuropathy. J Neurophysiol 1993;70:470-481.
21. Mao J, Price DD, Phillips LL, Lu J, Mayer DJ: Increases in protein kinase C gamma immunoreactivity in the spinal cord of rats associated with tolerance to the analgesic effects of morphine. Brain Res 1995;677:257-267.
22. Chen L, Huang LY: Sustained potentiation of NMDA receptor-mediated glutamate responses through activation of protein kinase C by a mu opioid. Neuron 1991;7:319-326.
23. 2+ block of NMDA-receptor channels as a mechanism of modulation. Nature 1992;356:521-523.
24. Mao J: Opioid-Induced abnormal pain sensitivity: Implications in clinical opioid therapy. Pain 2002;100:213-217.