Protective effect of lidocaine on injury alveolar Type II cells induced by LPS in adult rats

Journal of Central South University (Medical Sciences)

Volumn 31, Issue 2, 2006, Pages 241-244

  Xu, Dao Miao ^a   Ming, Guang Feng ^a   Wu, Xiao Ying ^b   Chen, Sheng Xi ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Central South University   (China)

Author keywords

Alveolar type II cells; Apoptosis; Injury; Lidocaine

Indexed keywords

LACTATE DEHYDROGENASE; LIDOCAINE; LIPOPOLYSACCHARIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DAMAGE; CELL DEATH; CONTROLLED STUDY; DRUG EFFECT; ELECTRON MICROSCOPE; FLOW CYTOMETRY; LUNG ALVEOLUS CELL TYPE 2; NONHUMAN; RAT;

ANIMALS; APOPTOSIS; CELLS, CULTURED; EPITHELIAL CELLS; FLOW CYTOMETRY; LACTATE DEHYDROGENASES; LIDOCAINE; LIPOPOLYSACCHARIDES; NECROSIS; PROTECTIVE AGENTS; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33646527376     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Crandall ED, Matthay MA. Alveolar epithelial transport. Basic science to clinical medicine[J]. Am J Respir Crit Care Med, 2001, 163(4): 1021-1029.
2. Matute-Bello G, Martin TR. Science review: apoptosis in acute lung injury[J]. Crit Care, 2003, 7(5): 355-358.
3. DePietro MR, Eichacker PQ. Lidocaine for acute lung injury: questions still to answer[J]. Crit Care Med, 2000, 28(2): 589-591.
4. Yamada A, Tanaka E, Niiyama S, et al. Protective actions of various local anesthetics against the membrane dysfunction produced by in vitro ischemia in rat hippocampal CA1 neurons [J]. Neurosci Res, 2004, 50(3): 291-298.
5. Dobbs LG. Isolation and culture of alveolar type II cells[J]. Am J Physiol. 1990, 258(4 Pt 1): L134-147.
6. Nishina K, Mikawa K, Morikawa O, et al. The effects of intravenous anesthetics and lidocaine on proliferation of cultured type II pneumocytes and lung fibroblasts[J]. Anesth Analg, 2002, 94(2): 385-388.
7. Huang TK, Uyehara CF, Balaraman V, et al. Surfactant lavage with lidocaine improves pulmonary function in piglets after HCl-induced acute lung injury[J]. Lung, 2004, 182(1): 15-25.
8. Matute-Bello G, Winn RK, Martin TR, et al. Sustained lipopolysaccharide - induced lung inflammation in mice is attenuated by functional deficiency of the Fas/Fas ligand system[J]. Clin Diagn Lab Immunol, 2004, 11(2): 358-361.
9. Clarke AR, Purdie CA, Harrison DJ, et al. Thymocyte apoptosis induced by p53-dependent and independent pathways [J]. Nature, 1993, 362(6423): 849-852.