Synthesis of an estradiol glucuronide derivative and investigation of its radiopharmaceutical potential

Applied Radiation and Isotopes

Volumn 64, Issue 7, 2006, Pages 778-788

  Biber, F Z ^a   Unak, P ^a   Ertay, T ^b   Medine, E I ^a   Zihnioglu, F ^a   Tasci, C ^a   Durak, H ^a  

^a EGE UNIVERSITY   (Turkey)

^b DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

estradiol (1,3,5, 10 estratrien 3,17 diol); 7,12 dimethylbenzantracene (DMBA); 99mTc ESTDTPA; 99mTc ESTDTPAG; DTPA; Estradiol derivative radiopharmaceuticals

Indexed keywords

AMINES; ENZYMES; MEDICAL IMAGING; RADIOLOGY; SYNTHESIS (CHEMICAL);

Β-ESTRADIOL (1,3,5,[10]-ESTRATRIEN-3,17Β-DIOL); 7,12-DIMETHYLBENZANTRACENE (DMBA); 99MTC-ESTDTPA; 99MTC-ESTDTPAG; DTPA; ESTRADIOL DERIVATIVE RADIOPHARMACEUTICALS;

RADIOACTIVE MATERIALS;

1,3,5[10] ESTRATRIENE 3,17BETA DIOL; BETA GLUCURONIDASE; DEOXY NORHOMOESTRADIOLYLDIETHYLENETRIAMINE PENTACETIC ACID; DEOXY NORHOMOESTRADIOLYLDIETHYLENETRIAMINE PENTACETIC ACID GLUCURONIDE TC 99M; ESTRADIOL; ESTROGEN RECEPTOR; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; PENTETIC ACID; RADIOPHARMACEUTICAL AGENT; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST TUMOR; CALCULATION; CHRONOLOGY; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG ACTIVITY; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG IDENTIFICATION; DRUG IMPURITY; DRUG PURIFICATION; DRUG RECEPTOR BINDING; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TISSUE LEVEL; DRUG UPTAKE; ENZYME ACTIVITY; FEMALE; GAMMA SCINTIGRAPHY; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE SYNTHESIS; ISOTOPE LABELING; LIPOPHILICITY; NONHUMAN; PRIORITY JOURNAL; RADIOCHEMISTRY; RADIOCHROMATOGRAPHY; RAT; RAT STRAIN; SCINTILLATION CAMERA; TARGET ORGAN; THIN LAYER CHROMATOGRAPHY; TIME SERIES ANALYSIS; TISSUE DISTRIBUTION; TUMOR; UTERUS; VARANGIAN;

ANIMALS; BREAST NEOPLASMS; ESTRADIOL; FEMALE; GLUCURONIDES; ISOTOPE LABELING; LIVER; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; TECHNETIUM; TECHNETIUM TC 99M PENTETATE; TISSUE DISTRIBUTION;

EID: 33646503033     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2006.02.001     Document Type: Article

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