Rational Design of GPCR-Specific Combinational Libraries Based on the Concept of Privileged Substructures

Chemoinformatics in Drug Discovery

Volumn 23, Issue , 2005, Pages 287-313

  Savchuk, Nikolay P ^a   Tkachenko, Sergey E ^a   Balakin, Konstantin V ^a  

^a CHEMDIV INC   (United States)

Author keywords

Combinatorial chemistry and rational drug design; Concepts of privileged substructures; Peripheral retrosynthetic fragments; Privileged structures; Rational design of GPCR specific combinational libraries; Rational selection of building blocks

Indexed keywords

BIOCHIPS; CONFORMAL MAPPING; DIGITAL LIBRARIES; LIBRARIES; SELF ORGANIZING MAPS;

BUILDING BLOCKES; CONCEPTS OF PRIVILEGED SUBSTRUCTURES; PERIPHERAL RETROSYNTHETIC FRAGMENTS; PRIVILEGED STRUCTURES; RATIONAL DESIGN; RATIONAL DRUG DESIGNS;

ARCHITECTURAL DESIGN;

EID: 33646497571     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/3527603743.ch12     Document Type: Chapter

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