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Volumn 32, Issue 3, 2006, Pages 267-275

Diagnosis and therapy of polycythemia vera

Author keywords

Diagnosis; Leukemia; Myelofibrosis; Polycythemia vera; Therapy; Thrombosis

Indexed keywords

ACETYLSALICYLIC ACID; ALKYLATING AGENT; ALPHA INTERFERON; ANAGRELIDE; ANTITHROMBOCYTIC AGENT; BUSULFAN; CHLORAMBUCIL; DIPYRIDAMOLE; HYDROXYUREA; IMATINIB; MOLECULAR MARKER; PHOSPHORUS; PIPOBROMAN; PLACEBO; PROTEIN TYROSINE KINASE;

EID: 33646491601     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-939438     Document Type: Review
Times cited : (5)

References (51)
  • 1
    • 0001639195 scopus 로고
    • Some speculations on the myeloproliferative syndromes
    • Dameshek W. Some speculations on the myeloproliferative syndromes. Blood 1951;6:372-375
    • (1951) Blood , vol.6 , pp. 372-375
    • Dameshek, W.1
  • 3
    • 0032757399 scopus 로고    scopus 로고
    • Histochemistry and morphometry on bone marrow specimens in chronic myeloproliferative disorders - Aids to diagnosis and classification
    • Thiele J, Kvasnicka HM, Fischer R, Diehl V. Histochemistry and morphometry on bone marrow specimens in chronic myeloproliferative disorders - aids to diagnosis and classification. Ann Hematol 1999;78:495-506
    • (1999) Ann Hematol , vol.78 , pp. 495-506
    • Thiele, J.1    Kvasnicka, H.M.2    Fischer, R.3    Diehl, V.4
  • 5
    • 2642609475 scopus 로고    scopus 로고
    • Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera
    • Moliterno A, Hankins D, Spivak J. Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera. N Engl J Med 1998;338:572-580
    • (1998) N Engl J Med , vol.338 , pp. 572-580
    • Moliterno, A.1    Hankins, D.2    Spivak, J.3
  • 6
    • 0242663394 scopus 로고    scopus 로고
    • Quantification of PRV-1 mRNA distinguishes polycythemia vera from secondary erythrocytosis
    • Klippel S, Strunck S, Temerinac S, et al. Quantification of PRV-1 mRNA distinguishes polycythemia vera from secondary erythrocytosis. Blood 2003;102:3569-3574
    • (2003) Blood , vol.102 , pp. 3569-3574
    • Klippel, S.1    Strunck, S.2    Temerinac, S.3
  • 7
    • 0037108844 scopus 로고    scopus 로고
    • Overexpression of the polycythemia rubra vera-1 gene in essential thrombocythemia
    • Teofili L, Martini M, Luongo M, et al. Overexpression of the polycythemia rubra vera-1 gene in essential thrombocythemia. J Clin Oncol 2002;20:4249-4254
    • (2002) J Clin Oncol , vol.20 , pp. 4249-4254
    • Teofili, L.1    Martini, M.2    Luongo, M.3
  • 8
    • 1542290175 scopus 로고    scopus 로고
    • Comparison of methods for polycythemia rubra vera-1 mRNA quantification in whole-blood leukocytes and purified granulocytes
    • Palmqvist L, Goerttler P, Wasslavik C, et al. Comparison of methods for polycythemia rubra vera-1 mRNA quantification in whole-blood leukocytes and purified granulocytes. Clin Chem 2004;50:644-647
    • (2004) Clin Chem , vol.50 , pp. 644-647
    • Palmqvist, L.1    Goerttler, P.2    Wasslavik, C.3
  • 9
    • 33646473808 scopus 로고    scopus 로고
    • Relationship of PRV1 expression and JAK2 V617F mutations in chronic myeloproliferative disorders
    • abst 409
    • Emig M, Ernst T, Schenk T, et al. Relationship of PRV1 expression and JAK2 V617F mutations in chronic myeloproliferative disorders. Onkologie 2005;28(suppl 3):136 (abst 409)
    • (2005) Onkologie , vol.28 , Issue.SUPPL. 3 , pp. 136
    • Emig, M.1    Ernst, T.2    Schenk, T.3
  • 10
    • 17644424955 scopus 로고    scopus 로고
    • A gain-of-function mutation of JAK2 in myeloproliferative disorders
    • Kralovics R, Passamonti F, Buser A, et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 2005;352:1779-1790
    • (2005) N Engl J Med , vol.352 , pp. 1779-1790
    • Kralovics, R.1    Passamonti, F.2    Buser, A.3
  • 11
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter E, Scott L, Campbell P, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005;365:1054-1061
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.1    Scott, L.2    Campbell, P.3
  • 12
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Couédic J, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-1148
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Couédic, J.3
  • 13
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine R, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005;7:387-397
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.1    Wadleigh, M.2    Cools, J.3
  • 14
    • 21344467318 scopus 로고    scopus 로고
    • Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders
    • Jones A, Kreil S, Zoi K, et al. Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders. Blood 2005;106:2162-2168
    • (2005) Blood , vol.106 , pp. 2162-2168
    • Jones, A.1    Kreil, S.2    Zoi, K.3
  • 15
    • 0028844554 scopus 로고
    • The natural history of 1213 patients followed for 20 years
    • Gruppo Italiano Studio Polycythemia vera. The natural history of 1213 patients followed for 20 years. Ann Intern Med 1995;123:656-664
    • (1995) Ann Intern Med , vol.123 , pp. 656-664
  • 16
    • 0028304056 scopus 로고
    • The very-long-term course of polycythemia: A complement to the previously published data of the polycythemia vera study group
    • Najean Y, Dresch C, Rain JD. The very-long-term course of polycythemia: a complement to the previously published data of the polycythemia vera study group. Br J Haematol 1994;86:233-235
    • (1994) Br J Haematol , vol.86 , pp. 233-235
    • Najean, Y.1    Dresch, C.2    Rain, J.D.3
  • 17
    • 0025820104 scopus 로고
    • Life expectancy of patients with chronic nonleukemic myeloproliferative disorders
    • Rozman C, Giralt M, Feliu E, Rubio D, Cortés MT. Life expectancy of patients with chronic nonleukemic myeloproliferative disorders. Cancer 1991;67:2658-2663
    • (1991) Cancer , vol.67 , pp. 2658-2663
    • Rozman, C.1    Giralt, M.2    Feliu, E.3    Rubio, D.4    Cortés, M.T.5
  • 18
    • 0037309554 scopus 로고    scopus 로고
    • Polycythemia vera in young patients: A study on the long-term risk of thrombosis, myelofibrosis and leukemia
    • Passamonti F, Malabarba L, Orlandi E, et al. Polycythemia vera in young patients: a study on the long-term risk of thrombosis, myelofibrosis and leukemia. Haematologica 2003;88:13-18
    • (2003) Haematologica , vol.88 , pp. 13-18
    • Passamonti, F.1    Malabarba, L.2    Orlandi, E.3
  • 19
    • 0023632575 scopus 로고
    • Polycythemia vera in young people. An analysis of 58 cases diagnosed before 40 years
    • Najean Y, Mugnier P, Dresch C, Rain J. Polycythemia vera in young people. An analysis of 58 cases diagnosed before 40 years. Br J Haematol 1987;67:285-291
    • (1987) Br J Haematol , vol.67 , pp. 285-291
    • Najean, Y.1    Mugnier, P.2    Dresch, C.3    Rain, J.4
  • 20
    • 0019378211 scopus 로고
    • Increased incidence of acute leukemia in polycythemia vera associated with chlorambucil therapy
    • Berk PD, Goldberg JD, Silverstein MN, et al. Increased incidence of acute leukemia in polycythemia vera associated with chlorambucil therapy. N Engl J Med 1981;304:441-447
    • (1981) N Engl J Med , vol.304 , pp. 441-447
    • Berk, P.D.1    Goldberg, J.D.2    Silverstein, M.N.3
  • 22
    • 0028956001 scopus 로고
    • Incidence of myelofibrosis following treatment of primary polycythaemia by venesection
    • Messinezy M, Pearson TC. Incidence of myelofibrosis following treatment of primary polycythaemia by venesection. Br J Haematol 1995;89:228-229
    • (1995) Br J Haematol , vol.89 , pp. 228-229
    • Messinezy, M.1    Pearson, T.C.2
  • 23
    • 0019488158 scopus 로고
    • Treatment of polycythemia vera by radiophosphorus or busulfan: A randomized trial
    • Haanen C, Mathé G, Hayat M. Treatment of polycythemia vera by radiophosphorus or busulfan: a randomized trial. Br J Cancer 1981;44:75-80
    • (1981) Br J Cancer , vol.44 , pp. 75-80
    • Haanen, C.1    Mathé, G.2    Hayat, M.3
  • 24
    • 0031000705 scopus 로고    scopus 로고
    • 32P alone or in combination with maintenance therapy using hydroxyurea in 461 patients greater than 65 years of age
    • 32P alone or in combination with maintenance therapy using hydroxyurea in 461 patients greater than 65 years of age. Blood 1997;89:2319-2327
    • (1997) Blood , vol.89 , pp. 2319-2327
    • Najean, Y.1    Rain, J.D.2
  • 25
    • 0031041044 scopus 로고    scopus 로고
    • From efficacy to safety: A polycythemia vera study group report on hydroxyurea in patients with polycythemia vera
    • Fruchtman SM, Mack K, Kaplan ME, Peterson P, Berk PD, Wasserman LR. From efficacy to safety: a polycythemia vera study group report on hydroxyurea in patients with polycythemia vera. Semin Hematol 1997;34:17-23
    • (1997) Semin Hematol , vol.34 , pp. 17-23
    • Fruchtman, S.M.1    Mack, K.2    Kaplan, M.E.3    Peterson, P.4    Berk, P.D.5    Wasserman, L.R.6
  • 26
    • 0031047488 scopus 로고    scopus 로고
    • Management of polycythemia vera with hydroxyurea
    • Tatarsky I, Sharon R. Management of polycythemia vera with hydroxyurea. Semin Hematol 1997;34:24-28
    • (1997) Semin Hematol , vol.34 , pp. 24-28
    • Tatarsky, I.1    Sharon, R.2
  • 27
    • 0030784247 scopus 로고    scopus 로고
    • Treatment of polycythemia vera: The use of hydroxyurea and pipobroman in 292 patients under the age of 65 years
    • Najean Y, Rain JD, for the French Polycythemia Study Group. Treatment of polycythemia vera: the use of hydroxyurea and pipobroman in 292 patients under the age of 65 years. Blood 1997;90:3370-3377
    • (1997) Blood , vol.90 , pp. 3370-3377
    • Najean, Y.1    Rain, J.D.2
  • 28
    • 0033781129 scopus 로고    scopus 로고
    • Second malignancies in patients with essential thrombocythemia treated with busulphan and hydroxyurea: Long-term follow up of a randomized trial
    • Finazzi G, Ruggeri M, Rodheghiero F, Barbui T. Second malignancies in patients with essential thrombocythemia treated with busulphan and hydroxyurea: long-term follow up of a randomized trial. Br J Haematol 2000;110:577-583
    • (2000) Br J Haematol , vol.110 , pp. 577-583
    • Finazzi, G.1    Ruggeri, M.2    Rodheghiero, F.3    Barbui, T.4
  • 29
    • 20144389274 scopus 로고    scopus 로고
    • Acute leukemia in polycythemia vera: An analysis of 1638 patients enrolled in a prospective observational study
    • ECLAP Investigators
    • Finazzi G, Caruso V, Marchioli R, et al. ECLAP Investigators. Acute leukemia in polycythemia vera: an analysis of 1638 patients enrolled in a prospective observational study. Blood 2005;105:2664-2670
    • (2005) Blood , vol.105 , pp. 2664-2670
    • Finazzi, G.1    Caruso, V.2    Marchioli, R.3
  • 30
    • 0021637379 scopus 로고
    • Efficacy trial of pipobroman in polycythemia vera and incidence of acute leukemia
    • Brusamolino E, Salvaneschi L, Canevari A, Bernasconi C. Efficacy trial of pipobroman in polycythemia vera and incidence of acute leukemia. J Clin Oncol 1984;2:558-561
    • (1984) J Clin Oncol , vol.2 , pp. 558-561
    • Brusamolino, E.1    Salvaneschi, L.2    Canevari, A.3    Bernasconi, C.4
  • 31
    • 0031804798 scopus 로고    scopus 로고
    • Polycythemia vera treated with pipobroman as single agent: Low incidence of secondary leukemia in a cohort of patients observed during 20 years (1971-1991)
    • Petti MC, Spadea A, Avvisati G, et al. Polycythemia vera treated with pipobroman as single agent: low incidence of secondary leukemia in a cohort of patients observed during 20 years (1971-1991). Leukemia 1998;12:869-874
    • (1998) Leukemia , vol.12 , pp. 869-874
    • Petti, M.C.1    Spadea, A.2    Avvisati, G.3
  • 32
    • 0033757965 scopus 로고    scopus 로고
    • Efficacy of pipobroman in the treatment of polycythemia vera: Long-term results in 163 patients
    • Passamonti F, Brusalimo E, Lazzarino M, et al. Efficacy of pipobroman in the treatment of polycythemia vera: long-term results in 163 patients. Haematologica 2000;85:1011-1018
    • (2000) Haematologica , vol.85 , pp. 1011-1018
    • Passamonti, F.1    Brusalimo, E.2    Lazzarino, M.3
  • 33
    • 0037715410 scopus 로고    scopus 로고
    • Long-term outcomes of polycythemia vera patients treated with pipobroman as initial therapy
    • Kiladjian JJ, Gardin C, Renoux M, Bruno F, Bernard JF. Long-term outcomes of polycythemia vera patients treated with pipobroman as initial therapy. Hematol J 2003;4:198-207
    • (2003) Hematol J , vol.4 , pp. 198-207
    • Kiladjian, J.J.1    Gardin, C.2    Renoux, M.3    Bruno, F.4    Bernard, J.F.5
  • 34
    • 0034037028 scopus 로고    scopus 로고
    • Interferon α in the treatment of polycythemia vera
    • Lengfelder E, Berger U, Hehlmann R. Interferon α in the treatment of polycythemia vera. Ann Hematol 2000;79:103-109
    • (2000) Ann Hematol , vol.79 , pp. 103-109
    • Lengfelder, E.1    Berger, U.2    Hehlmann, R.3
  • 35
    • 0032530861 scopus 로고    scopus 로고
    • Long term treatment of myeloproliferative disease with interferon-α-2b
    • Gilbert HS. Long term treatment of myeloproliferative disease with interferon-α-2b. Cancer 1998;83:1205-1213
    • (1998) Cancer , vol.83 , pp. 1205-1213
    • Gilbert, H.S.1
  • 36
    • 33646466285 scopus 로고    scopus 로고
    • Pegylated interferon alpha (PegIntron) in patients with polycythemia vera. A prospective multicenter phase II Study
    • abst O 363
    • Merx K, Fabarius A, Pahl H, et al. Pegylated interferon alpha (PegIntron) in patients with polycythemia vera. A prospective multicenter phase II Study. Onkologie 2004;27(suppl 3):74 (abst O 363)
    • (2004) Onkologie , vol.27 , Issue.SUPPL. 3 , pp. 74
    • Merx, K.1    Fabarius, A.2    Pahl, H.3
  • 37
    • 0037483282 scopus 로고
    • Anagrelide, a therapy for thrombocythemic states: Experience in 577 patients
    • Anagrelide study group. Anagrelide, a therapy for thrombocythemic states: experience in 577 patients. Am J Med 1992; 92:69-76
    • (1992) Am J Med , vol.92 , pp. 69-76
  • 38
    • 2442690281 scopus 로고    scopus 로고
    • Treatment paradigms in the management of myeloproliferative disorders
    • Fruchtman SM. Treatment paradigms in the management of myeloproliferative disorders. Semin Hematol 2004;41 (suppl 3):18-22
    • (2004) Semin Hematol , vol.41 , Issue.SUPPL. 3 , pp. 18-22
    • Fruchtman, S.M.1
  • 39
    • 0035865604 scopus 로고    scopus 로고
    • Long-term use of anagrelide in young patients with essential thrombocythemia
    • Storen E, Tefferi A. Long-term use of anagrelide in young patients with essential thrombocythemia. Blood 2001;97:863-866
    • (2001) Blood , vol.97 , pp. 863-866
    • Storen, E.1    Tefferi, A.2
  • 40
    • 21444434751 scopus 로고    scopus 로고
    • United Kingdom Medical Research Council Primary Thrombocythemia 1 Study. Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia
    • Harrison CN, Campbell PJ, Buck G, et al. United Kingdom Medical Research Council Primary Thrombocythemia 1 Study. Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. N Engl J Med 2005;353:33-45
    • (2005) N Engl J Med , vol.353 , pp. 33-45
    • Harrison, C.N.1    Campbell, P.J.2    Buck, G.3
  • 41
    • 0038717050 scopus 로고    scopus 로고
    • Imatinib mesylate (Gleevec™) reduces phlebotomy requirements in polycythemia vera
    • Silver RT. Imatinib mesylate (Gleevec™) reduces phlebotomy requirements in polycythemia vera. Leukemia 2003;17:1186-1187
    • (2003) Leukemia , vol.17 , pp. 1186-1187
    • Silver, R.T.1
  • 42
    • 33645734511 scopus 로고    scopus 로고
    • Imatinib mesylate (GLEEVEC) is effective in the treatment of polycythemia vera: A multi-institutional clinical trial
    • Silver RT, Fruchtman SM, Feldman EJ, Spivak JL, Salvado AJ. Imatinib mesylate (GLEEVEC) is effective in the treatment of polycythemia vera: a multi-institutional clinical trial. Blood 2004;104:(abst 656)
    • (2004) Blood , vol.104 , pp. 656
    • Silver, R.T.1    Fruchtman, S.M.2    Feldman, E.J.3    Spivak, J.L.4    Salvado, A.J.5
  • 43
    • 4644264248 scopus 로고    scopus 로고
    • Imatinib mesylate therapy reduces phlebotomy requirements in polycythemia vera
    • Hasselbalch HC, Pedersen M, Bostrom H. Imatinib mesylate therapy reduces phlebotomy requirements in polycythemia vera. Blood 2003;102:(abst 5087)
    • (2003) Blood , vol.102 , pp. 5087
    • Hasselbalch, H.C.1    Pedersen, M.2    Bostrom, H.3
  • 44
    • 33646481616 scopus 로고    scopus 로고
    • Imatinib mesylate therapy for patients with polycythemia vera
    • Borthakur G, Kantarjian H, Vesrtovsek S, et al. Imatinib mesylate therapy for patients with polycythemia vera. Blood 2004;104:(abst 1527)
    • (2004) Blood , vol.104 , pp. 1527
    • Borthakur, G.1    Kantarjian, H.2    Vesrtovsek, S.3
  • 45
    • 33646479605 scopus 로고    scopus 로고
    • Imatinib mesylate in polycythemia vera. A Heterogeneous Response pattern but a consistent reduction in phlebotomy requirements
    • abst 4747
    • Hasselbalch HC, Larsen TS, Henriksen AS, et al. Imatinib mesylate in polycythemia vera. A Heterogeneous Response pattern but a consistent reduction in phlebotomy requirements. Blood 2004;104:(abst 4747)
    • (2004) Blood , vol.104
    • Hasselbalch, H.C.1    Larsen, T.S.2    Henriksen, A.S.3
  • 46
    • 33646493790 scopus 로고    scopus 로고
    • A phase II trial of imatinib mesylate (Gleevec) in myeloproliferative disorders
    • abst 4765
    • Kuriakose P, Shurafa MS. A phase II trial of imatinib mesylate (Gleevec) in myeloproliferative disorders. Blood 2004;104:(abst 4765)
    • (2004) Blood , vol.104
    • Kuriakose, P.1    Shurafa, M.S.2
  • 47
    • 0037343949 scopus 로고    scopus 로고
    • Polycythemia vera responds to imatinib mesylate
    • Jones CM, Dickinson TM. Polycythemia vera responds to imatinib mesylate. Am J Med Sci 2003;325:149-152
    • (2003) Am J Med Sci , vol.325 , pp. 149-152
    • Jones, C.M.1    Dickinson, T.M.2
  • 48
    • 33646482221 scopus 로고    scopus 로고
    • Imatinib (Glivcc®) therapy in patients with polycythemia vera. Interim analyses of an open label phase II trial
    • abst 235
    • Merx K, Maywald O, Fabarius A, et al. Imatinib (Glivcc®) therapy in patients with polycythemia vera. Interim analyses of an open label phase II trial. Onkologie 2005;27(suppl 3):80 (abst 235)
    • (2005) Onkologie , vol.27 , Issue.SUPPL. 3 , pp. 80
    • Merx, K.1    Maywald, O.2    Fabarius, A.3
  • 49
    • 0022743990 scopus 로고
    • Adverse effects of antiaggregating platelet therapy in the treatment of polycythemia vera
    • Tartaglia A, Goldberg JD, Berk PD, Wasserman LR. Adverse effects of antiaggregating platelet therapy in the treatment of polycythemia vera. Semin Hematol 1986;23:172-176
    • (1986) Semin Hematol , vol.23 , pp. 172-176
    • Tartaglia, A.1    Goldberg, J.D.2    Berk, P.D.3    Wasserman, L.R.4
  • 50
    • 84983134916 scopus 로고    scopus 로고
    • Low dose aspirin in polycythemia vera: A pilot study
    • Gruppo Italiano Studio Polycythemia vera. Low dose aspirin in polycythemia vera: a pilot study. Br J Haematol 1997;97:453-456
    • (1997) Br J Haematol , vol.97 , pp. 453-456
  • 51
    • 0346727336 scopus 로고    scopus 로고
    • Efficacy and safety of low dose aspirin in polycythemia vera
    • Landolfi R, Marchioli R, Kutti J, et al. Efficacy and safety of low dose aspirin in polycythemia vera. N Engl J Med 2004;350:114-124
    • (2004) N Engl J Med , vol.350 , pp. 114-124
    • Landolfi, R.1    Marchioli, R.2    Kutti, J.3


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