Relationship between THC concentration in blood and impairment in apprehended drivers

Traffic Injury Prevention

Volumn 7, Issue 2, 2006, Pages 111-116

  Khiabani, Hassan Z ^a   Bramness, Jørgen G ^a   Bjørneboe, Anders ^a   Mørland, Jørg ^a  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

Author keywords

Cannabis; Drugged Driving; Psychomotor Impairment; THC Concentration

Indexed keywords

CANNABIS; DRONABINOL;

ADULT; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; DECISION MAKING; DRIVING ABILITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NORWAY; POLICE; PSYCHOMOTOR PERFORMANCE; RISK ASSESSMENT; TRAFFIC ACCIDENT;

ACCIDENTS, TRAFFIC; ADULT; AGE FACTORS; AUTOMOBILE DRIVING; DATA INTERPRETATION, STATISTICAL; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MARIJUANA ABUSE; PSYCHOMOTOR PERFORMANCE; RISK FACTORS; SEX FACTORS; SUBSTANCE ABUSE DETECTION; TETRAHYDROCANNABINOL;

EID: 33646491146     PISSN: 10286586     EISSN: 1538957X     Source Type: Journal    
DOI: 10.1080/15389580600550172     Document Type: Article

References (37)

1. Bachs L, Skurtveit S, Morland J. (2003) Codeine and clinical impairment in samples in which morphine is not detected. Eur. J. Clin. Pharmacol., Vol. 58, pp. 785-789.
2. Berghaus G, Kruger HP, Vollrath M. (1998a) Beeinträchtigung fahrrelevanter leistungen nach rauchen von cannabis und alcohol-consum. Eine vergleichende metaanalyse experimenteller studien, in Cannabis im StraBenverkehr, Ed. G. Berghaus, H.P. Kruger, G. Fisher, Verlag, Stuttgart, pp. 99-111.
3. Berghaus G, Schultz E, Szegedi A. (1998b) Cannabis und fahrtüchtigkeit. Ergebnisse der experimentelle forschung, in Cannabis im StraBenverkehr. Ed. G. Berghaus, H.P. Kruger, G. Fisher, Verlag, Stuttgart, pp. 73-97.
4. Blows S, Ivers RQ, Connor J, Ameratunga S, Woodward M, Norton R. (2005) Marijuana use and car crash injury, Addiction, Vol. 100, pp. 605-611.
5. Bramness JG, Skurtveit S, Morland J. (2002) Clinical impairment of benzodiazepines - relation between benzodiazepine concentrations and impairment in apprehended drivers. Drug and Alcohol Dependence, Vol. 68, pp. 131-141.
6. Bramness JG, Skurtveit S, Morland J. (2004) Impairment Due to Intake of Carisoprodol. Drug and Alcohol Dependence, Vol. 74, pp. 311-318.
7. Chait ED, Pierri J. (1992) Effects of smoked marijuana on human performance: A critical review, in Marijuana/Cannabinoids: Neurobiology and neurophysiology. Ed. E. Murphy, A. Bartke, CRC Press, Boca Raton, pp. 387-423.
8. Christophersen AS. (1986) Tetrahydrocannabinol stability in whole blood: Plastic versus glass containers. J. Anal.Toxicol., Vol. 10, pp. 129-131.
9. Christophersen AS, Gjerde H, Bjorneboe A, Sakshaug J, Morland J. (1990) Screening for drug use among Norwegian drivers suspected of driving under influence of alcohol or drugs. Forensic science international, Vol. 45, pp. 5-14.
10. Drummer, OH. (1994) Drugs in Drivers Killed in Australiana Road Traffic Accidents, Victorian Institute of Forensic Pathology, Institute of Forensic Medicine, Monash University, Melbourne, Australia, 0594.
11. Drummer OH, Gerostamoulos J, Batziris H, Chu M, Caplehorn JR, Robertson MD, Swann P. (2003) The incidence of drugs in drivers killed in Australian road traffic crashes. Forensic Science International, Vol. 134, pp. 154-162.
12. Drummer OH, Gerostamoulos J, Batziris H, Chu M, Caplehorn J, Robertson MD, Swann P (2004) The involvement of drugs in drivers of motor vehicles killed in Australian road traffic crashes. Accident Analysis and Prevention, Vol. 36, pp. 239-248.
13. Gjerde H. (1991) Screening for cannabinoids in blood using EMIT: Concentrations of delta-9-tetrahydrocannabinol in relation to EMIT results. Forensic Sci. Int, Vol. 50, pp. 121-124.
14. Gjerde H, Christophersen AS, Skuterud B, Klemetsen K, Morland J. (1990) Screening for drugs in forensic blood samples using EMIT urine assays, Forensic Sci. Int., Vol. 44, pp. 179-185.
15. Gjerde H, Kinn G. (1991) Impairment in drivers due to cannabis in combination with other drugs. Forensic Science International, Vol. 50, pp. 57-60.
16. Gmel, G. (2002) Cannabiskonsum in der Schweiz, Schweizerische Fachstelle für alkohol und andere drogenprobleme, Lausanne.
17. Gustafson RA, Moolchan ET, Barnes A, Levine B, Huestis MA. (2003) Validated method for the simultaneous determination of delta 9-tetrahydrocannabinol (THC), 11-hydroxy-THC and 11-nor-9-carboxy-THC in human plasma using solid phase extraction and gas chromatography-mass spectrometry with positive chemical ionization, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., Vol. 798, pp. 145-154.
18. Hall W, Degenhardt L, Lynskey, M. (2001) The Health and Psychological Effects of Cannabis Use, National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Monograph series no. 44.
19. Howlett AC, Breivogel CS, Childers SR, Deadwyler SA, Hampson RE, Porrino LJ. (2004) Cannabinoid physiology and pharmacology: 30 years of progress. Neuropharmacology, Vol. 47 Suppl 1, pp. 345-358.
20. Huestis MA, Henningfield JE, Cone EJ. (1992) Blood cannabinoids. I. Absorption of THC and formation of 11-OH-THC and THC-COOH during and after smoking marijuana. J. Anal. Toxicol., Vol. 16, pp. 276-282.
21. Hunter CE, Lokan RJ, Longo MC. (1998) The Prevalence and Role of Alchohol, Cannabinoids, Benzodiazepines and Stimulants in Non-Fatal Crashes, Forensic Science, Department of Administration and Information Services, Adelaide, South Australia.
22. Krüger H, Berghaus G. (1995) Behaviroral Effects of Alcohol and Cannabis: Can Equipotencies be Established?, in Alcohol, Drugs and Traffic Safety-T'95 Volume 1, Ed. Kloeden C, McLean AJ, NHMRC Road Accident Research Unit. The university of adelaide 5005, Adelaide, Australia.
23. Kuitunen T. (1994) Drug and ethanol effects on the clinical test for drunkenness: Single doses of ethanol, hypnotic drugs, and antidepressant drugs. Pharmacology and Toxicology, Vol. 75, pp. 91-98.
24. Kurzthaler I, Hummer M, Miller C, Sperner-Unterweger B, Gunther V, Wechdorn H, Battista HJ, Fleischhacker WW. (1999) Effect of cannabis use on cognitive functions and driving ability. J. Clin. Psychiatry, Vol. 60, pp. 395-399.
25. Leirer VO, Yesavage JA, Morrow DG. (1989) Marijuana, aging, and task difficulty effects on pilot performance, Aviat. Space Environ. Med., Vol. 60, pp. 1145-1152.
26. Mason AP, McBay AJ. (1984) Ethanol, marijuana, and other drug use in 600 drivers killed in single-vehicle crashes in North Carolina. 1978-1981. J. Forensic Sci., Vol. 29, pp. 987-1026.
27. Movig KL, Mathijssen MP, Nagel PH, van Egmond T, de Gier JJ, Leufkens HG, Egberts AC. (2004) Psychoactive substance use and the risk of motor vehicle accidents. Accident Analysis and Prevention, Vol. 36, pp. 631-636.
28. Peel HW, Perrigo BJ. (1981) Detection of cannabinoids in blood using EMIT. J. Anal. Toxicol., Vol. 5, pp. 165-167.
29. Ramaekers JG, Robbe HW, O'Hanlon JF. (2000) Marijuana, alcohol and actual driving performance. Hum. Psychopharmacol., Vol. 15, pp. 551-558.
30. Reeve VC, Grant JD, Robertson W, Gillespie HK, Hollister LE. (1983) Plasma concentrations of delta-9-tetrahydrocannabinol and impaired motor function, Drug and Alcohol Dependence, Vol. 11, pp. 167-175.
31. Robbe HW. (1994) Influence of Marijuana on Driving, University of Limburg, Maastricht, The Netherlands.
32. Sexton BF, Turnbridge RJ, Brook-Carter N, Jackson PG, Wright K, Stark MM, Englehart K. (2000) The Influence of Cannabis on Driving, Transport Research Foundation Limited (TRL), United Kingdom, 477.
33. Smiley AM, Moskowitz H, Ziedman K. (1981) Driving Simulator Studies of Marijuana Alone and in Combination with Alchohol, in Proceedings of the 25th Conference of the American Association for Automotive Medicine, American Association for Automotive Medicine, USA, pp. 107-116.
34. Terhune KW, Fell JC. (1982) The Role of Alchohol, Marijuana and Other Drugs in the Accidents of Injured Drivers, Calspan Field Services Inc., Buffalo, New York, Tech. Rep. under Contract No. DOT-HS-5-01179.
35. Terhune KW, Ippolito CA, Hendriks DL, Michalovic JG. (1992) The Incidence and Role of Drugs in Fatally Injured Drivers, National Highway Traffic Safety Administration, Final Report Under Contract No. DTNH 22-88-C-07069.
36. Tzambazis K, Stough C. (2002) The SFST and Driving Ability. Are They Related?, Ed. Dussault C, ICADTS, Montreal, Quebec, Canada.
37. Waller PF, Blow FC, Maio RF, Singer K, Hill EM, Schaefer N. (1997) Crash characteristics and injuries of victims impaired by alcohol versus illicit drugs. Accident Analysis and Prevention, Vol. 29, pp. 817-827.