The effect of organotin compounds on gender specific androstenedione metabolism in the freshwater ramshorn snail Marisa cornuarietis

Journal of Steroid Biochemistry and Molecular Biology

Volumn 99, Issue 2-3, 2006, Pages 147-156

  Janer, G ^a   Bachmann, J ^b   Oehlmann, J ^b   Schulte Oehlmann, U ^b   Porte, C ^a  

^a DEPARTMENT OF ENVIRONMENTAL CHEMISTRY   (Spain)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Androstenedione; Gastropod; Imposex; Organotin; Steroidogenesis

Indexed keywords

5ALPHA DIHYDROANDROSTENEDIONE; ANDROSTANOLONE; ANDROSTENEDIONE; ORGANOTIN COMPOUND; TESTOSTERONE 17BETA DEHYDROGENASE; TRIBUTYLTIN; TRIPHENYLTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FRESHWATER ENVIRONMENT; GASTROPOD; HORMONE METABOLISM; IN VITRO STUDY; MALE; MARISA CORNUARIETIS; NONHUMAN; SEX DIFFERENCE; SNAIL;

ANDROSTENEDIONE; ANIMALS; DIHYDROTESTOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GONADS; KINETICS; MALE; MICROSOMES; ORGANOTIN COMPOUNDS; SEX FACTORS; SNAILS; TESTOSTERONE; TIME FACTORS; TRIALKYLTIN COMPOUNDS; WATER POLLUTANTS;

GASTROPODA; MARISA CORNUARIETIS;

EID: 33646478553     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2005.12.003     Document Type: Article

References (30)

1. Mindnich R., Moller G., and Adamski J. The role of 17β-hydroxysteroid dehydrogenases. Mol. Cell. Endocrinol. 218 (2004) 7-20
2. Janer G., LeBlanc G.A., and Porte C. A comparative study on androgen metabolism in three invertebrate species. Gen. Comp. Endocrinol. 143 3 (2005) 211-221
3. Ollevier F., De Clerck D., Diederik H., and De Loof A. Identification of nonecdysteroid steroids in hemolymph of both male and female Astacus leptodactylus (Crustacea) by gas chromatography-mass spectrometry. Gen. Comp. Endocrinol. 61 2 (1986) 214-228
4. Bose R., Majumdar C., and Bhattacharya S. Steroids in Achatina fulica (Bowdich): steroid profile in haemolymph and in vitro release of steroids from endogenous precursors by ovotestis and albumen gland. Comp. Biochem. Physiol. C 116 (1997) 179-182
5. Verslycke T., De Wasch K., De Brabander H.F., and Janssen C.R. Testosterone metabolism in the estuarine mysid Neomysis integer (Crustacea; Mysidacea): identification of testosterone metabolites and endogenous vertebrate-type steroids. Gen. Comp. Endocrinol. 126 (2002) 190-199
6. Reis-Henriques M.A., LeGuellec D., Remy-Martin J.P., and Adessi G.L. Studies on endogenous steroid from the marine mollusc Mytilus edulis L. by gas chromatography and mass spectrometry. Comp. Biochem. Physiol. B 95 (1990) 303-309
7. Takeda N. Hormonal control of head-wart development in the snail Euchadra peliomphala. J. Embryol. Exp. Morphol. 60 (1980) 57-59
8. Spooner N., Gibbs P.E., Bryan G.W., and Goad L.J. The effect of tributyltin upon steroid titers in the female dogwhelk, Nucella lapillus, and the development of imposex. Mar. Environ. Res. 32 (1991) 37-49
9. Bettin C., Oehlmann J., and Stroben E. TBT-induced imposex in marine neogastropods is mediated by an increasing androgen level. Helgol. Meeresunters 50 (1996) 299-317
10. Oberdörster E., and McClellan-Green P. The neuropeptide APGWamide induces imposex in the mud snail, Ilyanassa obsoleta. Peptides 21 (2000) 1323-1330
11. Gottfried H., and Dorfman R.I. Steroids of invertebrates V. The in vitro biosynthesis of steroids by the male-phase ovotestis of the slug (Ariolimax californicus). Gen. Comp. Endocrinol. 15 (1970) 120-138
12. De Longcamp D., Lubet P., and Drosdowsky M. The in vitro biosynthesis of steroids by the gonad of the mussel (Mytilus edulis). Gen. Comp. Endocrinol. 22 (1974) 116-127
13. Gooding M.P., and LeBlanc G.A. Seasonal variation in the regulation of testosterone levels in the eastern mud snail (Ilyanassa obsoleta). Invert. Biol. 123 (2004) 237-243
14. Fent K. Ecotoxicology of organotin compounds. Crit. Rev. Toxicol. 26 (1996) 1-117
15. Gooding M.P., Wilson V.S., Folmar L.C., Marcovich D.T., and LeBlanc G.A. The biocide tributyltin reduces the accumulation of testosterone as fatty acid esters in the mud snail (Ilyanassa obsoleta). Environ. Health Perspect. 111 (2003) 426-430
16. Morcillo Y., Ronis M.J.J., and Porte C. Effects of tributyltin on the Phase I testosterone metabolism and steroid titres of the clam Ruditapes decussata. Aquat. Toxicol. 42 (1998) 1-13
17. Le Curieux-Belfond O., Moslemi S., Mathieu M., and Séralini G.E. Androgen metabolism in oyster Crassostera gigas: evidence for 17β-HSD activities and characterization of an aromatase-like activity inhibited by pharmacological compounds and a marine pollutant. J. Steroid Biochem. Mol. Biol. 78 (2001) 359-366
18. Morcillo Y., Albalat A., and Porte C. Mussels as sentinels of organotin pollution: bioaccumulation and effects on P450-mediated aromatase activity. Environ. Toxicol. Chem. 18 (1999) 1203-1208
19. Santos M.M., ten Hallers-Tjabbes C.C., Vieira N., Boon J.P., and Porte C. Cytochrome P450 differences in normal and imposex-affected female whelk Buccinum undatum from the open North Sea. Mar. Environ. Res. 54 3-5 (2002) 661-665
20. Ronis M.J.J., and Mason A.Z. The metabolism of testosterone by the periwinkle (Littorina littorea) in vitro and in vivo: effects of tribultyl tin. Mar. Environ. Res. 42 (1996) 161-166
21. Schulte-Oehlmann U., Bettin C., Fioroni P., Oehlmann J., and Stroben E. Marisa cornuarietis (Gastropoda, Prosobranchia): a potential TBT bioindicator for freshwater environments. Ecotoxicology 4 (1995) 372-384
22. Lowry O.M., Rosenbrough W.J., Farr A.L., and Randall R.J. Protein measurement with folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
23. Thibaut R., and Porte C. Effects of endocrine disrupters on sex steroid synthesis and metabolism pathways in fish. J. Steroid Biochem. Mol. Biol. 92 (2004) 485-494
24. Hines G.A., Bryan P.J., Wasson K.M., McClintock J.B., and Watts S.A. Sex steroid metabolism in the antarctic pteropod Clione antarctica (Mollusca: Gastropoda). Invert. Biol. 115 (1996) 113-119
25. Normington K., and Russell D.W. Tissue distribution and kinetic characteristics of rat steroid 5α-reductase isozymes. Evidence for distinct physiological functions. J. Biol. Chem. 267 (1992) 19548-19554
26. Lo S., Allera A., Albers P., Heimbrecht J., Jantzen E., Klingmüller D., and Steckelbroeck S. Dithioerythritol (DTE) prevents inhibitory effects of triphenyltin (TPT) on the key enzymes of the human sex steroid hormone metabolism. J. Steroid Biochem. Mol. Biol. 84 (2003) 569-576
27. Baldwin W.S., Graham S.E., Shea D., and LeBlanc G.A. Metabolic androgenization of female Daphnia magna by the xenoestrogen 4-nonylphenol. Environ. Toxicol. Chem. 16 (1997) 1905-1911
28. Oberdörster E., Rittschof D., and LeBlanc G.A. Alteration of [14C]-testosterone metabolism after chronic exposure of Daphnia magna to tributyltin. Arch. Environ. Contam. Toxicol. 34 1 (1998) 21-25
29. Verslycke T., Poelmans S., De Wasch K., De Brabander H.F., and Janssen C.R. Testosterone and energy metabolism in the estuarine mysid Neomysis integer (Crustacea: Mysidacea) following exposure to endocrine disruptors. Environ. Toxicol. Chem. 23 5 (2004) 1289-1296
30. G. Janer, A. Lyssimachou, J. Bachmann, J. Oehlmann, U. Schulte-Oehlmann, C. Porte, Sexual dimorphism in esterified steroid levels in the gastropod Marisa cornuarietis: the effect of xenoandrogenic compounds, Steroids, in press.