Suppressive effects of young radish cultivated with sulfur on growth and metastasis of B16-F10 melanoma cells

Archives of Pharmacal Research

Volumn 29, Issue 3, 2006, Pages 235-240

  Kim, Soo Jin ^a   Kim, Byung Sam ^a   Kyung, Tae Wook ^a   Lee, Sang Chul ^a   Rho, Chi Woong ^b   Choi, Kyung Rak ^b   Hwang, Hae Jun ^b   Choi, Hye Seon ^a  

^a University of Ulsan   (South Korea)

^b Gyeongsangnam do Agricultural Research and Extension Service   (South Korea)

Author keywords

Isothiocyanate; Melanoma; Quinone reductase; Radish; Sulfur

Indexed keywords

ANTINEOPLASTIC AGENT; GLUTATHIONE TRANSFERASE; PLANT EXTRACT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SULFORAFAN; SULFUR; THIOCYANIC ACID DERIVATIVE;

ANIMAL; ARTICLE; C57BL MOUSE; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; EXPERIMENTAL MELANOMA; LIVER; LUNG; LUNG TUMOR; MALE; METABOLISM; METASTASIS; MOUSE; PATHOLOGY; PLANT LEAF; RADISH;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE TRANSFERASE; LIVER; LUNG; LUNG NEOPLASMS; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NAD(P)H DEHYDROGENASE (QUINONE); PLANT EXTRACTS; PLANT LEAVES; RAPHANUS; SULFUR; THIOCYANATES;

EID: 33646472135     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF02969399     Document Type: Article

References (15)

1. Chung, F. L., Conaway, C. C., Rao, C. V., and Reddy, B. S., Chemoprevention of colonic aberrant cryptic foci in Fisher Rats by sulforaphane and phenethyl isothiocyanate. Carcinogenesis, 21, 2287-2291 (2000).
2. Fahey, J. W., Haristory, X., Dolan, P. M., Kensler, T. W., Scholtus, I., Stephenson, K. K., Talay, P., and Lozniewski, A., Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pyroli and prevents benzo[a]pyrene-induced stomach tumors. Proc. Natl. Acad. Sci. U.S.A., 99, 7610-7615 (2002).
3. Finley, J. W., Davis, C. D., and Feng, Y., Selenium from high selenium broccoli protects rats from colon cancer. J. Nutr., 130, 2384-2389 (2000).
4. Gao, X., Dinkova-Kostyova A. T., and Talalay, P., Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: The indirect antioxidant effects of sulforaphane. Proc. Natl. Acad. Sci. U.S.A., 98, 15221-15226 (2001).
5. Haenszel, W., Locke, F. B., and Segi, M., A case control study of large bowel cancer in Japan. J. Natl. Cancer Inst., 64, 17-22 (1980).
6. Hecht, S. S., Inhibition of carcinogenesis by isothiocyanates. Drug Metab. Rev., 32, 395-411 (2000).
7. Kim, K. A., Rho, C. W., Choi, K. R., Hwang, H. J., and Choi, H. S., Quinone Reductase Inducer from Radish Leaf Cultivated in the Soil Containing Sulfur. J. Korean Soc. Food Sci. Nutr., 33, 946-950 (2004).
8. Posner, G. H., Cho, C. G., Green, J. V., Zhang, Y., and Talalay, P., Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes. J. Med. Chem., 37, 170-176 (1994).
9. Watenberg, L. W., In Cancer chemoprevention. Eds.: Wattenberg, M., Lipkin, C. W., Boone, C. W., and Kelloff, F. L., CRC Press, Boca Raton, pp. 19-30, (1992).
10. Wortelboer, H. M., DeKruif, C. A., Van Lersel, A. A. J., Noorhoek, H. M., Blaauboer, B. J., Van Bladeren P. J., and Flake, H. E., Effects of cooked Brussels sprouts on cP450 profile and phase II enzymes in liver and small intestinal mucosa of the rat. Food Chem. Toxicol., 30, 589-599 (1992).
11. Zhang, Y., Talalay, P. Cho, C. G., and Posner, G. H., A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc. Natl. Acad. Sci. U.S.A., 89, 2399-2403 (1992).
12. Zhang, Y., Kensler, T. W., Cho, C.-G., posner, G. H., and Talay, P., Anticarcinogenic activities of sulforaphane and structurally related synthetic norbonyl isothiocyanates. Proc. Natl. Acad. Sci. U.S.A., 91, 3147-3150 (1994).
13. Zhang, Y. and Talalay, P., Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanism. Cancer Res. (suppl), 54, 1976s-1981s (1994).
14. Zhang, Y. and Talay, P., Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic phase 2 enzymes. Cancer Res., 58, 4632-4639 (1998).
15. Zhang, J., Svehlikova, V., Bao Y., Howie, A. F., Beckett, G. J., and Williamson, G., Synergy between sulforaphane and selenium in the induction of thioredoxin reductase 1 requires both transcriptional and translational modulation. Carcinogenesis, 24, 497-503 (2003).