-
1
-
-
0036731485
-
Stats: Transcriptional control and biological impact
-
Levy, D. E., and Darnell, J. E., Jr. (2002) Stats: transcriptional control and biological impact, Nat. Rev. Mol. Cell Biol. 3, 651-662.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell Jr., J.E.2
-
2
-
-
0028349735
-
Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
-
Zhong, Z., Wen, Z., and Darnell, J. E., Jr. (1994) Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6, Science 264, 95-98.
-
(1994)
Science
, vol.264
, pp. 95-98
-
-
Zhong, Z.1
Wen, Z.2
Darnell Jr., J.E.3
-
3
-
-
0026770248
-
Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
-
Schinder, C., Shuai, K., Prezioso, V. R., and Darnell, J. E. (1992) Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor, Science 257, 809-813.
-
(1992)
Science
, vol.257
, pp. 809-813
-
-
Schinder, C.1
Shuai, K.2
Prezioso, V.R.3
Darnell, J.E.4
-
4
-
-
0027493650
-
A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma
-
Shuai, K., Stark, G. R., Kerr, I. M., and Darnell, J. E. (1993) A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma, Science 261, 1744-1746.
-
(1993)
Science
, vol.261
, pp. 1744-1746
-
-
Shuai, K.1
Stark, G.R.2
Kerr, I.M.3
Darnell, J.E.4
-
5
-
-
0031443156
-
Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells
-
Garcia, R., Yu, C. L., Hudnall, A., Catlett, R., Nelson, K. L., Smithgall, T., Fujita, D. J., Eithier, S. P., and Jove, R. (1997) Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells, Cell Growth Differ. 8, 1267-1276.
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 1267-1276
-
-
Garcia, R.1
Yu, C.L.2
Hudnall, A.3
Catlett, R.4
Nelson, K.L.5
Smithgall, T.6
Fujita, D.J.7
Eithier, S.P.8
Jove, R.9
-
6
-
-
0013689209
-
Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth in vitro
-
Grandis, J. R., Drenning, S. D., Chakraborty, A., Zhou, M. Y., Zeng, Q., Pitt, A. S., and Tweardy, D. J. (1998) Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth In vitro, J. Clin. Invest. 102, 1385-1392.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1385-1392
-
-
Grandis, J.R.1
Drenning, S.D.2
Chakraborty, A.3
Zhou, M.Y.4
Zeng, Q.5
Pitt, A.S.6
Tweardy, D.J.7
-
7
-
-
0029784886
-
Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell line
-
Weber-Nordt, R. M., Egen, C., Wehinger, J., Ludwig, W., Gouilleux-Gruart, V., Mertelsmann, R., and Finke, J. (1996) Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell line, Blood 88, 809-816.
-
(1996)
Blood
, vol.88
, pp. 809-816
-
-
Weber-Nordt, R.M.1
Egen, C.2
Wehinger, J.3
Ludwig, W.4
Gouilleux-Gruart, V.5
Mertelsmann, R.6
Finke, J.7
-
8
-
-
0029066128
-
Differentiation-regulated serine phosphorylation of STAT1 promotes GAF activation in macrophages
-
Eilers, A., Georgellis, D., Klose, B., Schindler, C., Ziemiecki, A., Harpur, A. G., Wilks, A. F., and Decker, T. (1995) Differentiation-regulated serine phosphorylation of STAT1 promotes GAF activation in macrophages, Mol. Cell Biol. 15, 3579-3586.
-
(1995)
Mol. Cell Biol.
, vol.15
, pp. 3579-3586
-
-
Eilers, A.1
Georgellis, D.2
Klose, B.3
Schindler, C.4
Ziemiecki, A.5
Harpur, A.G.6
Wilks, A.F.7
Decker, T.8
-
9
-
-
0029117304
-
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen, Z., Zhong, Z., and Darnell, J. E., Jr. (1995) Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation, Cell 82, 241-250.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnell Jr., J.E.3
-
10
-
-
0028942656
-
Requirement of serine phosphorylation for formation of STAT-promoter complexes
-
Zhang, X., Blenis, J., Li, H. C., Schindler, C., and Chen-Kiang, S. (1995) Requirement of serine phosphorylation for formation of STAT-promoter complexes, Science 267, 1990-1994.
-
(1995)
Science
, vol.267
, pp. 1990-1994
-
-
Zhang, X.1
Blenis, J.2
Li, H.C.3
Schindler, C.4
Chen-Kiang, S.5
-
11
-
-
0030744123
-
Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3
-
Wen, Z., and Darnell, J. E., Jr. (1997) Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3, Nucleic Acids Res. 25, 2062-2067.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2062-2067
-
-
Wen, Z.1
Darnell Jr., J.E.2
-
12
-
-
0032515146
-
Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells
-
Yamashita, H., Xu, J., Erwin, R. A., Farrar, W. L., Kirken, R. A., and Rui, H. (1998) Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells, J. Biol. Chem. 273, 30218-30224.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30218-30224
-
-
Yamashita, H.1
Xu, J.2
Erwin, R.A.3
Farrar, W.L.4
Kirken, R.A.5
Rui, H.6
-
13
-
-
0030772458
-
STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation
-
Chung, J., Uchida, E., Grammer, T. C., and Blenis, J. (1997) STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation, Mol. Cell. Biol. 17, 6508-6516.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6508-6516
-
-
Chung, J.1
Uchida, E.2
Grammer, T.C.3
Blenis, J.4
-
14
-
-
0033598839
-
Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway
-
Kovarik, P., Stoiber, D., Eyers, P. A., Menghini, R., Neininger, A., Gaestel, M., Cohen, P., and Decker, T. (1999) Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway, Proc. Natl. Acad. Sci. U.S.A. 96, 13956-13961.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 13956-13961
-
-
Kovarik, P.1
Stoiber, D.2
Eyers, P.A.3
Menghini, R.4
Neininger, A.5
Gaestel, M.6
Cohen, P.7
Decker, T.8
-
15
-
-
0033834679
-
The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6
-
Zhang, T., Kee, WH., Seow, KH., Fung, W., and Cao, X. (2000) The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6, Mol. Cell. Biol. 20, 7132-7139.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7132-7139
-
-
Zhang, T.1
Kee, W.H.2
Seow, K.H.3
Fung, W.4
Cao, X.5
-
16
-
-
0033588229
-
Protein kinase C deka associates with and phosphorylates Stat3 in an interleukin-6-dependent manner
-
Jain, N., Zhang, T., Kee, W. H., Li, W., and Cao, X. (1999) Protein kinase C deka associates with and phosphorylates Stat3 in an interleukin-6-dependent manner, J. Biol. Chem. 274, 24392-24400.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 24392-24400
-
-
Jain, N.1
Zhang, T.2
Kee, W.H.3
Li, W.4
Cao, X.5
-
17
-
-
0033968596
-
Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR
-
Yokogami, K., Wakisaka, S., Avruch, J., and Reeves, S. A. (2000) Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR, Curr Biol. 10, 47-50.
-
(2000)
Curr Biol.
, vol.10
, pp. 47-50
-
-
Yokogami, K.1
Wakisaka, S.2
Avruch, J.3
Reeves, S.A.4
-
18
-
-
0034677195
-
Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways
-
Ramana, C. V., Grammalikakis, N., Chernov, M., Nguyen, H., Goh, K. C., Williams, B. R., and Stark, G. R. (2000) Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways, EMBO J. 19, 263-272.
-
(2000)
EMBO J.
, vol.19
, pp. 263-272
-
-
Ramana, C.V.1
Grammalikakis, N.2
Chernov, M.3
Nguyen, H.4
Goh, K.C.5
Williams, B.R.6
Stark, G.R.7
-
19
-
-
0034658024
-
Serine phosphorylation of STATs
-
Decker, T., and Kovarik, P. (2000) Serine phosphorylation of STATs, Oncogene 19, 2628-2637.
-
(2000)
Oncogene
, vol.19
, pp. 2628-2637
-
-
Decker, T.1
Kovarik, P.2
-
20
-
-
0035433029
-
Past and future of the mitotic spindle as an oncology target
-
Wood, K. W., Cornwell, W. D., and Jackson, J. R. (2001) Past and future of the mitotic spindle as an oncology target, Curr. Opin. Pharmacol. 1, 370-377.
-
(2001)
Curr. Opin. Pharmacol.
, vol.1
, pp. 370-377
-
-
Wood, K.W.1
Cornwell, W.D.2
Jackson, J.R.3
-
21
-
-
0037113913
-
Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells
-
Zhang, H., Shi, X., Zhang, Q. J., Hampong, M., Paddon, H., Wahyuningsih, D., and Pelech, S. (2002) Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells, J. Biol. Chem. 277, 43648-43658.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43648-43658
-
-
Zhang, H.1
Shi, X.2
Zhang, Q.J.3
Hampong, M.4
Paddon, H.5
Wahyuningsih, D.6
Pelech, S.7
-
22
-
-
4143144444
-
B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1
-
Zhang, H., Shi, X., Paddon, H., Hampong, M., Dai, W., and Pelech, S. (2004) B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1, J. Biol. Chem. 279, 35726-35734.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 35726-35734
-
-
Zhang, H.1
Shi, X.2
Paddon, H.3
Hampong, M.4
Dai, W.5
Pelech, S.6
-
23
-
-
0029916933
-
Activation and association of Stat3 with Src in v-Src-transformed cell lines
-
Cao, X., Tay, A., Guy, G. R., and Tan, Y. H. (1996) Activation and association of Stat3 with Src in v-Src-transformed cell lines, Mol. Cell. Biol. 16, 1595-1603.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1595-1603
-
-
Cao, X.1
Tay, A.2
Guy, G.R.3
Tan, Y.H.4
-
24
-
-
0037258952
-
Kinetworks protein-kinase multiblot analysis
-
Pelech, S., Sutter, C., and Zhang, H. (2003) Kinetworks protein-kinase multiblot analysis, Methods Mol. Biol. 218, 99-111.
-
(2003)
Methods Mol. Biol.
, vol.218
, pp. 99-111
-
-
Pelech, S.1
Sutter, C.2
Zhang, H.3
-
25
-
-
0034089542
-
Structure-based design modifications of the paullone molecular scaffold for cyclin-dependent kinase inhibition
-
Gussio, R., Zaharevitz, D. W., McGrath, C. F., Pattabiraman, N., Kellogg, G. E., Schultz, C., Link, A., Kunick, C., Leost, M., Meijer, L., and Sausville, E. A. (2000) Structure-based design modifications of the paullone molecular scaffold for cyclin-dependent kinase inhibition, Anticancer Drug Des. 15, 53-66.
-
(2000)
Anticancer Drug Des.
, vol.15
, pp. 53-66
-
-
Gussio, R.1
Zaharevitz, D.W.2
McGrath, C.F.3
Pattabiraman, N.4
Kellogg, G.E.5
Schultz, C.6
Link, A.7
Kunick, C.8
Leost, M.9
Meijer, L.10
Sausville, E.A.11
-
26
-
-
0036710767
-
Pharmacological inhibitors of cyclin-dependent kinases
-
Knockaert, M., Greengard, P., and Meijer, L. (2002) Pharmacological inhibitors of cyclin-dependent kinases, Trends Pharmacol. Sci. 23, 417-425.
-
(2002)
Trends Pharmacol. Sci.
, vol.23
, pp. 417-425
-
-
Knockaert, M.1
Greengard, P.2
Meijer, L.3
-
27
-
-
0025881168
-
Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase
-
dark-Lewis, I., Sanghera, J. S., and Pelech, S. L. (1991) Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase, J. Biol. Chem. 266, 15180-15184.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 15180-15184
-
-
Dark-Lewis, I.1
Sanghera, J.S.2
Pelech, S.L.3
-
28
-
-
0037321745
-
Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila
-
Chen, X., Oh, S. W., Zheng, Z., Chen, H. W., Shin, H. H., and Hou, S. X. (2003) Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila, Dev. Cell 4, 179-190.
-
(2003)
Dev. Cell
, vol.4
, pp. 179-190
-
-
Chen, X.1
Oh, S.W.2
Zheng, Z.3
Chen, H.W.4
Shin, H.H.5
Hou, S.X.6
-
29
-
-
2342483179
-
Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity
-
Fu, A. K., Fu, W. Y., Ng, A. K., Chien, W. W., Ng, Y. P., Wang, J. H., and Ip, N. Y. (2004) Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity, Proc. Natl. Acad. Sci. U.S.A. 101, 6728-6733.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 6728-6733
-
-
Fu, A.K.1
Fu, W.Y.2
Ng, A.K.3
Chien, W.W.4
Ng, Y.P.5
Wang, J.H.6
Ip, N.Y.7
-
30
-
-
0028122011
-
A brain-specific activator of cyclin-dependent kinase 5
-
Lew, J., Huang, Q. Q., Qi, Z., Winkfein, R. J., Aebersold, R., Hunt, T., and Wang, J. H. (1994) A brain-specific activator of cyclin-dependent kinase 5, Nature 371, 423-426.
-
(1994)
Nature
, vol.371
, pp. 423-426
-
-
Lew, J.1
Huang, Q.Q.2
Qi, Z.3
Winkfein, R.J.4
Aebersold, R.5
Hunt, T.6
Wang, J.H.7
-
31
-
-
0033538452
-
Regulation of angiotensin II-induced phosphorylation of STAT3 in vascular smooth muscle cells
-
Liang, H., Venema, V. J., Wang, X., Ju, H., Venema, R. C., and Marrero, M. B. (1999) Regulation of angiotensin II-induced phosphorylation of STAT3 in vascular smooth muscle cells, J. Biol. Chem. 274, 19846-19851.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19846-19851
-
-
Liang, H.1
Venema, V.J.2
Wang, X.3
Ju, H.4
Venema, R.C.5
Marrero, M.B.6
-
32
-
-
0030882317
-
STAT3 is a serine kinase target in T lymphocytes. Interleukin 2 and T cell antigen receptor signals converge upon serine 727
-
Ng, J., and Cantrell, D. (1997) STAT3 is a serine kinase target in T lymphocytes. Interleukin 2 and T cell antigen receptor signals converge upon serine 727, J. Biol. Chem. 272, 24542-24549.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24542-24549
-
-
Ng, J.1
Cantrell, D.2
-
33
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
Sherr, C. J., and Roberts, J. M. (1999) CDK inhibitors: positive and negative regulators of G1-phase progression, Genes Dev. 13, 1501-1512.
-
(1999)
Genes Dev.
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
34
-
-
0037474270
-
Opposite regulation of myc and p21waf1 transcription by STAT3 proteins
-
Barre, B., Avril, S., and Coqueret, O. (2003) Opposite regulation of myc and p21waf1 transcription by STAT3 proteins, J. Biol. Chem. 278, 2990-2996.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2990-2996
-
-
Barre, B.1
Avril, S.2
Coqueret, O.3
-
35
-
-
0034705540
-
Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1
-
Coqueret, O., and Gascan, H. (2000) Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1, J. Biol. Chem. 275, 18794-18800.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18794-18800
-
-
Coqueret, O.1
Gascan, H.2
-
36
-
-
0034612529
-
STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: Role for the cyclin-dependent kinase inhibitor p27(Kip1)
-
de Koning, J. P., Soede-Bobok, A. A., Ward, A. C., Schelen, A. M., Antonissen, C., van Leeuwen, D., Lowenberg, B., and Touw, I. P. (2000) STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: role for the cyclin-dependent kinase inhibitor p27(Kip1), Oncogene 19, 3290-3298.
-
(2000)
Oncogene
, vol.19
, pp. 3290-3298
-
-
De Koning, J.P.1
Soede-Bobok, A.A.2
Ward, A.C.3
Schelen, A.M.4
Antonissen, C.5
Van Leeuwen, D.6
Lowenberg, B.7
Touw, I.P.8
-
37
-
-
0028963841
-
p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
-
Macleod, K. F., Sherry, N., Hannon, G., Beach, D., Tokino, T., Kinzler, K., Vogelstein, B., and Jacks, T. (1995) p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage, Genes Dev. 9, 935-944.
-
(1995)
Genes Dev.
, vol.9
, pp. 935-944
-
-
Macleod, K.F.1
Sherry, N.2
Hannon, G.3
Beach, D.4
Tokino, T.5
Kinzler, K.6
Vogelstein, B.7
Jacks, T.8
-
38
-
-
0032952584
-
p21-(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption
-
Stewart, Z. A., Leach, S. D., and Pietenpol, J. A. (1999) p21-(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption, Mol. Cell. Biol. 19, 205-215.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 205-215
-
-
Stewart, Z.A.1
Leach, S.D.2
Pietenpol, J.A.3
|