A phase 1 and pharmacokinetic study of gemcitabine and oxaliplatin in patients with solid tumors

Cancer Chemotherapy and Pharmacology

Volumn 58, Issue 2, 2006, Pages 157-164

  Gan, Hui K ^a   Mitchell, Paul L ^a   Galettis, Peter ^b   Davis, Ian D ^a   Cebon, Jonathan ^a   De Souza, Paul ^b   Links, Matthew ^b  

^a AUSTIN HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Gemcitabine; Mesothelioma; Neurotoxicity; Oxaliplatin; Pharmacokinetics; Phase 1

Indexed keywords

GEMCITABINE; MITOMYCIN; NITROSOUREA; OXALIPLATIN;

ADULT; AGED; ALOPECIA; AREA UNDER THE CURVE; ARTICLE; BLOOD TOXICITY; BONE MARROW SUPPRESSION; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; DIARRHEA; DOSE RESPONSE; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MECHANISM; DRUG TOLERABILITY; DYSARTHRIA; DYSESTHESIA; FATIGUE; FEBRILE NEUTROPENIA; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMAN; LIVER DYSFUNCTION; MALE; MAXIMUM TOLERATED DOSE; MESOTHELIOMA; MUCOSA INFLAMMATION; NAUSEA; NEUROTOXICITY; NEUTROPENIA; PARESTHESIA; PERIPHERAL NEUROPATHY; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SOLID TUMOR; THROMBOCYTOPENIA; VOMITING;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; AREA UNDER CURVE; DEOXYCYTIDINE; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; ORGANOPLATINUM COMPOUNDS;

EID: 33646469699     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-005-0152-y     Document Type: Article

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