Analysis of metabolic fluxes for hyaluronic acid (HA) production by Streptococcus zooepidemicus

World Journal of Microbiology and Biotechnology

Volumn 22, Issue 4, 2006, Pages 399-408

  Gao, Hai Jun ^a   Du, Guo Cheng ^b   Chen, Jian ^b  

^a BEIJING INSTITUTE OF TECHNOLOGY   (China)

^b JIANGNAN UNIVERSITY   (China)

Author keywords

Dissolved oxygen tension (DOT); Fermentation; Hyaluronic acid; Metabolic flux analysis (MFA); Streptococcus zooepidemicus

Indexed keywords

BACTERIA; BIOMASS; CARBOXYLIC ACIDS; CELLS; FERMENTATION; OXYGEN;

DISSOLVED OXYGEN TENSION (DOT); HYALURONIC ACID; METABOLIC FLUX ANALYSIS (MFA); STREPTOCOCCUS ZOOEPIDEMICUS;

METABOLISM;

STREPTOCOCCUS EQUI SUBSP. ZOOEPIDEMICUS;

EID: 33646457371     PISSN: 09593993     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11274-005-9047-7     Document Type: Article

References (27)

1. Akasaka, H.M., Umasaki, H., Yanagi, M. & Kabushiki, K.S. 1983 Method of hyaluronic acid production Nihon kokai tokyo koho sho-58-56692 (Japan patent).
2. Armstrong, D.C., Cooney, M.J. & Johns, M.R. 1997 Growth and amino acid requirements of hyaluronic-acid-producing Streptococcus zooepidemicus. Applied Microbiology and Biotechnology 47, 309-312.
3. Atkinson, B. & Mavituna, F. 1991 Biochemical Engineering and Biotechnology Handbook, England: Macmillan publishers, ISBN 1561590126.
4. Barker, S.B. & Summerson, W.H. 1941 The colormetric determination of lactic acid in biological material. Journal of Biological Chemistry 138, 535-554.
5. Bitter, T. & Muri, H.M. 1962 A modified uronic acid carbazol reaction. Analytical Biochemistry 4, 330-334.
6. Bruinenberg, P.M., van Dijken, J.P. & Scheffers, W.A. 1983 A theoretical analysis of NADPH production and consumption in yeasts. Journal of General Microbiology 129, 953-964.
7. Buchanan, R.E. & Gibbons, N.E. 1974 Bergey's Manual of Determinative Bacteriology, 8th edition, Baltimore: Willams & Wilkins Company, ISBN 0683011170.
8. Crater, D.L. & Van de Rijn, I. 1995 Hyaluronic acid synthesis operon (has) expression in group A Streptococci. Journal of Biological Chemistry 270, 18452-18458.
9. De Luca, C., Lansing, M., Martin, I., Crescemzi, F., Shen, G.J., O'Reagan, M. & Wong, C.-H. 1995 Enzymatic synthesis of hyaluronic acid with regeneration of sugar nucleotides. Journal of the American Chemistry Society 117, 5869-5870.
10. Dorfman, A. 1955 Metabolism of mucopolysaccharides of connective tissue. Pharmacological Reviews 7, 1-13.
11. Dougherty, B.A. & de van Rijn, I. 1994 Molecular Characterize of hasA from an operon required for hyaluronic acid Synthesis in Group A streptococci. Journal of Biological Chemistry 269, 169-175.
12. Holmstrom, B. & Ricica, J. 1967 Production of hyaluronic acid by a Streptoccal strain in batch culture. Applied Microbiology 15, 1409-1413.
13. Johns, M.R., Goh, L.T. & Oeggerli, A. 1994 Effect of pH, agitation and aeration on hyaluronic acid produced by streptococcus zooepidemicus. Biotechnology Letters 16, 507-512.
14. Kim, J.H., Yoo, S.J., Oh, D.K., Kweon, Y.G., Park, D.W., Lee, C.H. & Gil, G.H. 1996 Selection of a Streptococcus equi mutant and optimization of culture conditions for the production of molecular weight hyaluronic acid. Enzyme and Microbial Technology 19, 440-445.
15. Markovitz, A., Cifonello, J.A. & Dorfman, A. 1959 The biosynthesis of hyaluronic acid by group A streptococcus. Journal of Biological Chemistry 234, 2343-2350.
16. Miller, G.L. 1960 Dinitrosalicylic acid reagent for determination of reducing sugar. Analytical Chemistry 31, 426-428.
17. Milligan, T.W., Doran, T.I., Straus, D.C. & Mattingly, S.J. 1978 Growth and amino acid requirements of various strains of group B streptococci. Journal of Clinical Microbiology 7, 28-33.
18. Nielson, J., Villadsen, J. & Lidén, G. 2003 Bioreaction Engineering Principles, NY: Kluwer Academic/Plenum press, ISBN 0306473496.
19. Nimrod, A., Greenman, B. & Landsberg, M. 1986 Method of producing high molecular weight sodium hyaluronate by fermentation of streptococcus. PCTpatent. WO 86/04355: PCT/US86/00066.
20. O'Regan, M., Martini, I., Crescenzi, F., de Luca, C. & Lansing, M. 1994 Molecular mechanisms and genetics of hyaluronan biosynthesis. International Journal of Biological Macromolecules 16, 283-286.
21. Sedewitz, B., Schleifer, K.H. & Gotz, F. 1984 Physiological role of pyruvate oxidase in the aerobic mechanism of Lactobacillus plantarum. Journal of Bacteriology 160, 462-465.
22. Stephanopoulos, G. & Vallino, J.J. 1991 Net rigidity and metabolic engineering in metabolic overproduction. Science 252, 1675-1681.
23. Swann, D.A. & Kuo, J.W. 1991 Hyaluronic acid. Biomaterials - Novel Materials from Biological Sources, In: Byrom D (ed.), New York, NY: Stockton Press. ISBN 1561590371.
24. Terleckyi, B. & Shockman, G.D. 1975 Amino acid requirements of Streptococcus mutants and other oral Streptococci. Infection and Immunity 11, 656-664.
25. Vallino, J.J. & Stephanopoulos, G. 1993 Metabolic flux distributions in Corynebaxterium glutamicum during growth and lysine over-production. Biotechnology and Bioengineering 41, 633-646.
26. Van Dijken, W.M. & Heijnen, J.J.A. 1995 Metabolic network stoichiometry analysis of microbial growth and product formation. Biotechnology and Bioengineering 48, 681-698.
27. 13C NMR. Biotechnology and Bioengineering 45, 292-303.