Effects of antiepileptics phenytoin, zonisamide and valproate on bone metabolism in growing rats

International Congress Series

Volumn 1284, Issue , 2005, Pages 87-88

  Takahashi, Atsushi ^a   Onodera, Kenji ^b   Saito, Takashi ^a   Sugawara, Masato ^c   Shinoda, Hisashi ^c   Mayanagi, Hideaki ^a,c  

^a Tohoku University Dental Hospital   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

Antiepileptic agent; Bone disorder; Bone mineral density; Osteopenia

Indexed keywords

EID: 33646454887     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/j.ics.2005.06.102     Document Type: Review

References (3)

1. Hunter J., et al. Altered calcium metabolism in epileptic children on anticonvulsants. Br. Med. J. 4 (1971) 202-204
2. Onodera K., et al. Phenytoin-induced bone loss and its prevention with alfacalcidol or calcitriol in growing rats. Calcif. Tissue Int. 69 (2001) 109-116
3. Takahashi A., et al. Effects of chronic administration of zonisamide, an antiepileptic drug, on bone mineral density and their prevention with alfacalcidol in growing rats. J. Pharmacol. Sci. 91 (2003) 313-318