The role of mitomycin C in reducing recurrence of epidural fibrosis after repeated operation in a laminectomy model in rats

Journal of Neurosurgery: Spine

Volumn 4, Issue 4, 2006, Pages 329-333

  Lee, Jin Yul ^a   Stenzel, Werner ^a   Löhr, Mario ^a   Stützer, Hartmut ^a   Ernestus, Ralf Ingo ^a   Klug, Norfrid ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Antibiotic therapy; Laminectomy; Peridural fibrosis; Rat; Repeated surgery

Indexed keywords

MITOMYCIN C; ALKYLATING AGENT; MITOMYCIN;

ADHESION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DURA MATER; EPIDURAL SPACE; FIBROSIS; HISTOLOGY; LAMINECTOMY; LUMBAR SPINE; MALE; NEUROLOGIC DISEASE; NONHUMAN; RECURRENT DISEASE; REPEAT PROCEDURE; SCAR FORMATION; ANIMAL; CHI SQUARE DISTRIBUTION; PATHOLOGY; POSTOPERATIVE COMPLICATION; RAT; REOPERATION; WISTAR RAT;

ADHESIONS; ALKYLATING AGENTS; ANIMALS; CHI-SQUARE DISTRIBUTION; EPIDURAL SPACE; FIBROSIS; LAMINECTOMY; MALE; MITOMYCIN; POSTOPERATIVE COMPLICATIONS; RATS; RATS, WISTAR; RECURRENCE; REOPERATION;

EID: 33646453386     PISSN: 15475654     EISSN: None     Source Type: Journal    
DOI: 10.3171/spi.2006.4.4.329     Document Type: Article

References (34)

1. Baba H, Chen Q, Kamitani K, Imura S, Tomita K: Revision surgery for lumbar disc herniation. An analysis of 45 patients. Int Orthop 19:98-102, 1995
2. Benoist M, Ficat C, Baraf P, Cauchoix J: Postoperative lumbar epiduro-arachnoiditis. Diagnostic and therapeutic aspects. Spine 5:432-436, 1980
3. Bernard TN Jr: Using computed tomography/discography and enhanced magnetic resonance imaging to distinguish between scar tissue and recurrent lumbar disc herniation. Spine 19:2826-2832, 1994
4. Burton CV, Kirkaldy-Willis WH, Yong-Hing K, Heithoff KB: Causes of failure of surgery on the lumbar spine. Clin Orthop Relat Res 157:191-199, 1981
5. Cabukoǧlu C, Güven O, Yildirim Y, Kara H, Ramadan SS: Effect of sagittal plane deformity of the lumbar spine on epidural fibrosis formation after laminectomy: an experimental study in the rat. Spine 29:2242-2247, 2004
6. Cauchoix J, Ficat C, Girard B: Repeat surgery after disc excision. Spine 3:256-259, 1978
7. Cooper RG, Mitchel WS, Illingworth KJ, Forbes WS, Gillespie JE, Jayson MI: The role of epidural fibrosis and defective fibrinolysis in the persistence of postlaminectomy back pain. Spine 16:1044-1048, 1991
8. de La Porte C, Siegfried J: Lumbosacral spinal fibrosis (spinal arachnoiditis). Its diagnosis and treatment by spinal cord stimulation. Spine 8:593-603, 1983
9. Devulder J, Bogaert L, Castille F, Moerman A, Rolly G: Relevance of epidurography and epidural adhesiolysis in chronic failed back surgery patients. Clin J Pain 11:147-150, 1995
10. Dullerud R, Graver V, Haakonsen M, Haaland AK, Loeb M, Magnaes B: Influence of fibrinolytic factors on scar formation after lumbar discectomy. A magnetic resonance imaging follow-up study with clinical correlation performed 7 years after surgery. Spine 23:1464-1469, 1998
11. Fager CA, Freidberg SR: Analysis of failures and poor results of lumbar spine surgery. Spine 5:87-94, 1980
12. Fandino J, Botana C, Viladrich A, Gomez-Bueno J: Reoperation after lumbar disc surgery: results in 130 cases. Acta Neurochir (Wien) 122:102-104, 1993
13. Ferguson B, Gray SD, Thibeault S: Time and dose effects of mitomycin C on extracellular matrix fibroblasts and proteins. Laryngoscope 115:110-115, 2005
14. Finnegan WJ, Fenlin JM, Marvel JP, Nardini RJ, Rothman RH: Results of surgical intervention in the symptomatic multiply-operated back patient: analysis of sixty-seven cases followed for three to seven years. J Bone Joint Surg Am 61:1077-1082, 1979
15. Grane P: The post-operative lumbar spine. A radiological investigation of the lumbar spine after discectomy using MR imaging and CT. Acta Radiol Suppl 414:1-23, 1998
16. Herron L: Recurrent lumbar disc herniation: results of repeat laminectomy and discectomy. J Spinal Disord 7:161-166, 1994
17. Hoyland JA, Freemont AJ, Denton J, Thomas AM, McMillan JJ, Jayson MI: Retained surgical swab debris in post-laminectomy arachnoiditis and peridural fibrosis. J Bone Joint Surg Br 70:659-662, 1988
18. Johnston JD, Matheny JB: Microscopic lysis of lumbar adhesive arachnoiditis. Spine 3:36-39, 1978
19. Jönsson B, Strömqvist B: Repeat decompression of lumbar nerve roots. A prospective two-year evaluation. J Bone Joint Surg Br 75:894-897, 1993
20. Kim SS, Michelsen CB: Revision surgery for failed back surgery syndrome. Spine 17:957-960, 1992
21. Law JD, Lehman RA, Kirsch WM: Reoperation after lumbar intervertebral disc surgery. J Neurosurg 48:259-263, 1978
22. Lee JY, Stenzel W, Ebel H, Wedekind C, Ernestus RI, Klug N: Mitomycin C in preventing spinal epidural fibrosis in a laminectomy model in rats. J Neurosurg 100 (1 Suppl):52-55, 2004
23. Lewis PJ, Weir BKA, Broad RW, Grace MG: Long-term prospective study of lumbosacral discectomy. J Neurosurg 67: 49-53, 1987
24. Long DM, McAfee PC: Reoperation on lumbar spine, in Atlas of Spinal Surgery. Baltimore: Williams & Wilkins, 1992, pp 23-57
25. Merrild U, Sogaard I: Sciatica caused by perifibrosis of the sciatic nerve. J Bone Joint Surg Br 68:706, 1986
26. North RB, Campbell JN, James CS, Conover-Walker MK, Wang H, Piantadosi S, et al: Failed back surgery syndrome: 5-year follow-up in 102 patients undergoing repeated operation. Neurosurgery 28:685-691, 1991
27. Nykvist F, Hurme M, Alaranta H, Kaitsaari M: Severe sciatica: a 13-year follow-up of 342 patients. Eur Spine J 4:335-338, 1995
28. Raiskup F, Solomon A, Landau D, Ilsar M, Frucht-Pery J: Mitomycin C for pterygium: long term evaluation. Br J Ophthalmol 88:1425-1428, 2004
29. Ross JS, Robertson JT, Frederickson RC, Petrie JL, Obuchowski N, Modic MT, et al: Association between peridural scar and recurrent radicular pain after lumbar discectomy: magnetic resonance evaluation. ADCON-L European Study Group. Neurosurgery 38:855-863, 1996
30. Shiraishi T, Crock HV: Re-exploration of the lumbar spine following simple discectomy: a review of 23 cases. Eur Spine J 4:84-87, 1995
31. Silvers HR, Lewis PJ, Asch HL, Clabeaux DE: Lumbar diskectomy for recurrent disc herniation. J Spinal Disord 7:408-419, 1994
32. Siqueira EB, Kranzler LI, Dharkar DD: Fibrosis of the dura mater. A cause of "failed back" syndrome. Surg Neurol 19:168-170, 1983
33. Thomalske G, Galow W, Ploke G: Critical comments on a comparison of two series (1000 patients each) of lumbar disc surgery. Adv Neurosurg 4:22-27, 1977
34. Yonemura Y, Fujimura T, Fushida S, Takegawa S, Kamata K, Katayama K, et al: Hyperthermo-chemotherapy combined with cytoreductive surgery for the treatment of gastric cancer with peritoneal dissemination. World J Surg 15:530-536, 1991