Isolation of hepatocytes from livers from non-heart-beating donors for cell transplantation

Liver Transplantation

Volumn 12, Issue 5, 2006, Pages 713-717

  Hughes, Robin D ^a   Mitry, Ragai R ^a   Dhawan, Anil ^a   Lehec, Sharon C ^a   Girlanda, Raffaele ^a   Rela, Mohamed ^a   Heaton, Nigel D ^a   Muiesan, Paolo ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7; COLLAGENASE;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD CLOTTING FACTOR 7 DEFICIENCY; CELL ISOLATION; CELL POPULATION; CELL VIABILITY; CHILD; CLINICAL ARTICLE; CLINICAL PROTOCOL; CORRELATION ANALYSIS; CRIGLER NAJJAR SYNDROME; CRYOPRESERVATION; DISEASE DURATION; FEMALE; FREEZE THAWING; GOOD MANUFACTURING PRACTICE; HEART BEAT; HEPATOCYTE TRANSPLANTATION; HIGH TEMPERATURE PROCEDURES; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; LIVER BIOPSY; LIVER DISEASE; LIVER ISCHEMIA; LIVER METABOLISM; LIVER PARENCHYMA; LIVER PERFUSION; LOW TEMPERATURE PROCEDURES; MALE; NEEDLE BIOPSY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; BIOPSY; CELL SEPARATION; CHILD; FEMALE; HEART ARREST; HEPATOCYTES; HUMANS; INFANT; LIVER; MALE; MIDDLE AGED; TISSUE DONORS;

EID: 33646452424     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.20732     Document Type: Article

References (21)

1. Horslen SP, Fox IJ. Hepatocyte transplantation. Transplantation 2004;77:1481-1486.
2. Fox IJ, Roy-Chowdhury J. Hepatocyte transplantation. J Hepatol 2004;40:878-886.
3. Strom SC, Fisher RA, Thompson MT, Sanyal AJ, Cole PE, Ham JM, et al. Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure. Transplantation 1997;63:559-569.
4. Bilir BM, Guinette D, Karrer F, Kumpe DA, Krysl J, Stephens J, et al. Hepatocyte transplantation in acute liver failure. Liver Transplant 2000;6:32-40.
5. Fox IJ, Chowdhury JR, Kaufman SS, Goertzen TC, Chowdhury NR, Warkentin PI, et al. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation. N Engl J Med 1998;338:1422-1426.
6. Muraca M, Gerunda G, Neri D, Vilei MT, Granato A, Feltracco P, et al. Hepatocyte transplantation as a treatment for glycogen storage disease type 1a. Lancet 2002;359: 317-318.
7. Horslen SP, McCowan TC, Goertzen TC, Warkentin PI, Cai HB, Strom SC, et al. Isolated hepatocyte transplantation in an infant with a severe urea cycle disorder. Pediatrics 2003;111:1262-1267.
8. Dhawan A, Mitry RR, Hughes RD, Lehec C, Terry C, Bansal S, et al. Hepatocyte transplantation for inherited factor VII deficiency. Transplantation 2004;78:1812-1814.
9. Muiesan P. Can controlled non-heart-beating donors provide a solution to the organ shortage? Transplantation 2003;75:1627-1628.
10. Reddy S, Zilvetti M, Brockmann J, McLaren A, Friend P. Liver transplantation from non-heart-beating donors: current status and future prospects. Liver Transpl 2004;10: 1223-1232.
11. Muiesan P, Girlanda R, Jassem W, Vilca Melendez H, O'Grady J, Bowles M, et al. Single center experience with liver transplantation from controlled non-heart beating donors: a viable source of grafts. Ann Surg 2005;242:732-738.
12. Strom SC, Dorko K, Thompson MT, Pisarov LA, Nussler AK. Large scale isolation and culture of human hepatocytes. In: Franco D, Boudjema K, Varet B, eds. Îlots de Langerhans et hépatocytes. Paris: Les Editions INSERM; 1998:195.
13. Mitry RR, Hughes RD, Aw MM, Terry C, Mieli-Vergani G, Girlanda R, et al. Human hepatocyte isolation and relationship of cell viability to early graft function. Cell Transplant 2003;12:69-74.
14. Diener B, Utesch D, Beer N, Durk H, Oesch F. A method for the cryopreservation of liver parenchymal cells for studies of xenobiotics. Cryobiology 1993;30: 116-127.
15. Hughes RD, Mitry RR, Dhawan A. Hepatocyte transplantation for metabolic liver disease: UK experience. J R Soc Med 2005;98:341-345.
16. Mitry RR, Dhawan A, Hughes RD, Bansal S, Lehec C, Terry C, et al. One liver, three recipients - segment IV from split liver procedures as a source of hepatocytes for cell transplantation. Transplantation 2004;77:1614-1616.
17. Terry C, Mitry RR, Lehec SC, Muiesan P, Rela M, Heaton ND, et al. The effects of cryopreservation on human hepatocytes obtained from different sources of liver tissue. Cell Transplant 2005;14:585-594
18. Ikeda T, Yanaga K, Kishikawa K, Kakizoe S, Shimada M, Sugimachi K. Ischemic injury in liver transplantation: difference in injury sites between warm and cold ischemia in rats. Hepatology 1992;16:454-461.
19. Abt PL, Desai NM, Crawford MD, Forman LM, Markmann JW, Olthoff KM, Markmann JF. Survival following liver transplantation from non-heart-beating donors. Ann Surg 2004;239:87-92.
20. Jassem W, Koo DD, Muiesan P, Cerundolo L, Rela M, Fuggle SV, Heaton ND. Non-heart-beating versus cadaveric and living-donor livers: differences in inflammatory markers before transplantation. Transplantation 2003; 75:1386-1390.
21. Vilca Melendez H, Rela M, Murphy G, Heaton N. Assessment of graft function before liver transplantation: quest for the lost ark? Transplantation 2000;70:560-565.