Lipophilic statins merit additional study for breast cancer chemoprevention [3]

Journal of Clinical Oncology

Volumn 24, Issue 13, 2006, Pages 2128-2129

  Prowell, Tatiana M ^a   Stearns, Vered ^a   Trock, Bruce ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PRAVASTATIN;

BREAST CANCER; CANCER CELL; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG SAFETY; HORMONE SUBSTITUTION; HUMAN; IN VIVO STUDY; LETTER; LIPOPHILICITY; MEDICAL STUDENT; META ANALYSIS; POSTMENOPAUSE; PRESCRIPTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTEMATIC REVIEW; TREATMENT CONTRAINDICATION; TREATMENT DURATION; BREAST TUMOR; FEMALE; NOTE;

BREAST NEOPLASMS; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; RANDOMIZED CONTROLLED TRIALS;

EID: 33646450434     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2005.05.1649     Document Type: Letter

References (4)

1. Bonovas S, Filioussi K, Tsavaris N, et al: Use of statins and breast cancer: A meta-analysis of seven randomized clinical trials and nine observational studies. J Clin Oncol 23:8606-8612, 2005
2. Seeger H, Wallwiener D, Mueck AO: Statins can inhibit proliferation of human breast cancer cells in vitro. Exp Clin Endocrinol Diabetes 111:47-48, 2003
3. Esserman L, Campbell M, Shoemaker M, et al: Breast cancer inhibition by statins. J Clin Oncol 23:97s, 2004 (suppl; abstr 1003)
4. Kochhar R, Khurana V, Bejjanki H, et al: Statins to reduce breast cancer risk: A case control study in U.S. female veterans. J Clin Oncol 23:7s, 2005 (suppl; abstr 514)