An outbreak of Serratia marcescens bloodstream infections associated with misuse of drug vials in a surgical ward

Infection Control and Hospital Epidemiology

Volumn 27, Issue 1, 2006, Pages 79-82

  Pan, Angelo ^a,e   Dolcetti, Lucia ^b   Barosi, Catia ^c   Catenazzi, Patrizia ^b   Ceruti, Tomaso ^d   Ferrari, Lucio ^d   Magri, Silvia ^e   Roldan, Eugenia Quiros ^e   Soavi, Laura ^e   Carnevale, Giuseppe ^a  

^a Divisione di Malattie Infettive   (Italy)

^b Direzione Sanitaria   (Italy)

^c Servizio di Farmacia   (Italy)

^d Laboratorio di Microbiologia   (Italy)

^e UNIVERSITY OF BRESCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; CARBAPENEM DERIVATIVE; CEPHALOSPORIN DERIVATIVE; GLUCOSE; IMIPENEM; INSULIN; MEROPENEM; PEFLOXACIN; PLASMA SUBSTITUTE; POLIGELINE; QUINOLONE DERIVATIVE; TETRACYCLINE; UNCLASSIFIED DRUG; UREIDOPENICILLIN DERIVATIVE;

ADULT; AGED; ARTICLE; BACTERIUM CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG CONTAMINATION; DRUG MISUSE; DRUG STORAGE; ENTEROBACTER INFECTION; HUMAN; MALE; SEPSIS; SERRATIA MARCESCENS; SURGICAL WARD; TOTAL PARENTERAL NUTRITION; BACTEREMIA; COMMUNITY HOSPITAL; CROSS INFECTION; DRUG PACKAGING; EPIDEMIC; HAND WASHING; HOSPITAL SUBDIVISIONS AND COMPONENTS; ITALY; MIDDLE AGED; PRACTICE GUIDELINE;

AGED; AGED, 80 AND OVER; BACTEREMIA; CROSS INFECTION; DISEASE OUTBREAKS; DRUG CONTAMINATION; DRUG PACKAGING; GUIDELINE ADHERENCE; HANDWASHING; HOSPITAL UNITS; HOSPITALS, COMMUNITY; HUMANS; ITALY; MALE; MIDDLE AGED; SERRATIA INFECTIONS; SERRATIA MARCESCENS;

EID: 33646444317     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/500250     Document Type: Article

References (19)

1. Alfizah H, Nordiah AJ, Rozaidi WS. Using pulse-field gel electrophoresis in the molecular investigation of an outbreak of S. marcescens infection in an intensive care unit. Singapore Med J 2004; 45:214-218.
2. Furusyo N, Kubo N, Nakashima H, Kashigawi K, Etoh Y, Hayashi J. Confirmation of nosocomial hepatitis C virus infection in a hemodialysis unit. Infect Control Hosp Epidemiol 2004; 25:584-590.
3. Grohskopf LA, Roth VR, Feikin DR, et al. Serratia liquefaciens blood-stream infections from contamination of epoietin alfa at a hemodialysis center. N Engl J Med 2001; 344:1491-1497.
4. Magee L, Godsiff L, Matthew I, Farrington M, Park GR. Anesthetic drugs and bacterial contamination. Eur J Anaesthesiol Suppl 1995; 12:41-43.
5. Pegues DA, Arathoon EG, Samoya B, et al. Epidemic gram-negative bacteremia in a neonatal intensive care unit in Guatemala. Am J Infect Control 1994;22:163-171.
6. Kirschke DL, Jones TF, Craig AS, et al. Pseudomonas aeruginosa and Serratia marcescens contamination associated with a manufacturing defect in bronchoscopes. N Engl J Med 2003; 348:214-220.
7. Miranda-Novales MG, Gordillo-Perez MG, Solorzano-Santos F, Leanos-Miranda B, Villasis-Keever MA, Villegas-Silva R. Case-control study of an outbreak of S. marcescens in a neonatal intensive care unit [in Spanish]. Rev Invest Clin 1998; 50:13-18.
8. Boyce JM, Pittet D. Guideline for hand hygiene in health-care settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/API/IDSA Hand Hygiene Task Force. MMWR Recomm Rep 2002; 51:1-45.
9. Pittet D, Mourouga P, Perneger TV, et al. Compliance with hand washing in a teaching hospital. Ann Intern Med 1999; 130:126-130.
10. National Committee for Clinical Laboratory Standards. Approved standard M7-A5: methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. 5th ed. Villanova, PA: National Committee for Clinical Laboratory Standards, 2000.
11. Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ATS/ SIS International Sepsis Definitions Conference. Intensive Care Med 2003; 29:530-538.
12. Jang TN, Fung CP, Yang TL, Shen SH, Huang CS, Lee SH. Use of pulsed-field gel electrophoresis to investigate an outbreak of Serratia marcescens infection in a neonatal intensive care unit. J Hosp Infect 2001; 48:13-19.
13. Wilhelmi I, Bernaldo de Quiros JC, Romero-Vivas J, Duarte J, Rojo E, Bouza E. Epidemic outbreak of Serratia marcescens infection in a cardiac surgery unit. J Clin Microbiol 1987; 25:1298-1300.
14. Pittet D, Hugonnet S, Harbarth S, et al. Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Infection Control Programme. Lancet 2000; 356:1307-1312.
15. Blogg CE, Ramsay MA, Jarvis JD. Infection hazard from syringes. Br J Anaesth 1974; 46:260-262.
16. Haddy RI, Mann BL, Nadkarni DD, et al. Nosocomial infection in the community hospital: severe infection due to Serratia species. J Fam Pract 1996; 42:273-277.
17. Yu WL, Lin CW, Wang DY. Serratia marcescens bacteremia: clinical features and antimicrobial susceptibilities of the isolates. J Microbiol Immunol Infect 1998; 31:171-179.
18. Bochud PY, Calandra T. Pathogenesis of sepsis: new concepts and implications for future treatment. BMJ 2003; 326:262-266.
19. Harbarth S, Garbino J, Pugin J, Romand JA, Lew D, Pittet D. Inappropriate initial antimicrobial therapy and its effect on survival in a clinical trial of immunomodulating therapy for severe sepsis. Am J Med 2003; 115:529-535.