Human herpesvirus 6 causes hepatitis in transplant recipients

Internal Medicine

Volumn 45, Issue 7, 2006, Pages 417-418

  Yoshikawa, Tetsushi ^a  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Hepatitis; HHV 6; HSCT

Indexed keywords

AMINOTRANSFERASE; FOSCARNET; GANCICLOVIR; VIRUS ANTIGEN; VIRUS DNA; VIRUS RNA;

AMINOTRANSFERASE BLOOD LEVEL; CHRONIC HEPATITIS; CLINICAL FEATURE; DIAGNOSTIC ACCURACY; DISEASE COURSE; EDITORIAL; EXANTHEMA SUBITUM; EXCHANGE BLOOD TRANSFUSION; FATALITY; GRAFT RECIPIENT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEPATITIS; HERPES VIRUS INFECTION; HISTOPATHOLOGY; HUMAN; HUMAN CYTOMEGALOVIRUS; HUMAN HERPESVIRUS 6; IMMUNE DEFICIENCY; IN SITU HYBRIDIZATION; INCIDENCE; INFECTION RISK; ORGAN TRANSPLANTATION; POLYMERASE CHAIN REACTION; RISK FACTOR; SEQUENCE HOMOLOGY; VIRUS REACTIVATION; VIRUS VIRULENCE;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEPATITIS, VIRAL, HUMAN; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 6, HUMAN; HUMANS; IMMUNOCOMPETENCE; IMMUNOCOMPROMISED HOST; INFANT; MIDDLE AGED; TRANSPLANTS;

EID: 33646437243     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.45.0147     Document Type: Editorial

References (12)

1. Salahuddin SZ, Ablashi DV, Markham PD, et al. Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders. Science 234: 596-601, 1986.
2. Yamanishi K, Okuno T, Shiraki K, et al. Identification of human herpesvirus-6 as a causal agent for exanthem subitum. Lancet 1: 1065-1067, 1988.
3. Yoshikawa T, Suga S, Asano Y, Yazaki T, Kodama H, Ozaki T. Distribution of antibodies to a causative agent of exanthem subitum (human herpesvirus-6) in healthy individuals. Pediatrics 84: 675-677, 1989.
4. Suga S, Yoshikawa T, Asano Y, et al. Clinical and virological analyses of 21 infants with exanthem subitum (roseola infantum) and central nervous system complications. Ann Neurol 33: 597-603, 1993.
5. Asano Y, Yoshikawa T, Suga S, Yazaki T, Kondo K, Yamanishi K. Fatal fulminant hepatitis in an infant with human herpesvirus-6 infection. Lancet 335: 862-863, 1990.
6. Asano Y, Nakashima T, Yoshikawa T, Suga S, Yazaki T. Severity of human herpesvirus-6 viremia and clinical findings in infants with exanthem subitum. J Pediatr 118: 891-895, 1991.
7. Tajiri H, Tanaka-Taya K, Ozaki Y, Okada S, Mushiake S, Yamanishi K. Chronic hepatitis in an infant, in association with human herpesvirus-6 infection. J Pediatr 131: 473-475, 1997.
8. Aita K, Jin Y, Irie H, et al. Are there histopathologic characteristics particular to fulminant hepatic failure caused by human herpesvirus-6 infection? A case report and discussion. Hum Pathol 32: 887-889, 2001.
9. Ishikawa K, Hasegawa K, Naritomi T, et al. Prevalence of herpesviridae and hepatitis virus sequences in the livers of patients with fulminant hepatitis of unknown etiology in Japan. J Gastroenterol 37: 523-530, 2002.
10. Yoshikawa T. Human herpesvirus 6 infection in hematopoietic stem cell transplant patients. Br J Haematol 124: 421-432, 2004.
11. Kuribayashi K, Matsunaga T, Iyama S, et al. Human herpesvirus 6 hepatitis associated with Cyclosporine-A encephalitis after bone marrow transplantation for chronic myeloid leukemia. Intern Med 45: 475-478, 2006.
12. Singh N, Paterson DL. Encephalitis caused by human herpesvirus-6 in transplant recipients: relevance of a novel neurotropic virus. Transplantation 69: 2474-2479, 2000.