Malignant acanthosis nigricans, tripe palms and the sign of Leser-Tre'lat, a hint to the diagnosis of early stage ovarian cancer: A case report and review of the literature

Gynecologic Oncology

Volumn 101, Issue 2, 2006, Pages 353-355

  Kebria, Mehdi M ^a   Belinson, Jerome ^a   Kim, Robert ^a   Mekhail, Tarek M ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Malignant acanthosis nigricans; Ovarian cancer; The sign of Leser Tre'lat; Tripe palms

Indexed keywords

CARBOPLATIN; PACLITAXEL;

ABDOMINAL HYSTERECTOMY; ACANTHOSIS NIGRICANS; ADULT; ARTICLE; CANCER CHEMOTHERAPY; CASE REPORT; CLINICAL EXAMINATION; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; CONVALESCENCE; EARLY CANCER; ECHOGRAPHY; FEMALE; HAND PALM; HUMAN; LAPAROTOMY; NUCLEAR MAGNETIC RESONANCE IMAGING; OVARY ADENOCARCINOMA; PELVIS LYMPHADENECTOMY; PRIORITY JOURNAL; SALPINGOOOPHORECTOMY; SEBORRHEIC KERATOSIS; SKIN BIOPSY; SKIN MALFORMATION; SKIN MANIFESTATION; SKINFOLD; TREATMENT OUTCOME;

ACANTHOSIS NIGRICANS; FEMALE; HAND DERMATOSES; HUMANS; KERATODERMA, PALMOPLANTAR; KERATOSIS, SEBORRHEIC; MIDDLE AGED; OVARIAN NEOPLASMS; PARANEOPLASTIC SYNDROMES; SKIN DISEASES;

EID: 33646426401     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2005.12.024     Document Type: Article

References (33)

1. Andreev V.C. Malignant acanthosis nigricans. Semin. Dermatol. 3 (1984) 265-272
2. Schwartz R.A. Acanthosis nigricans. J. Am. Acad. Dermatol. 31 (1994) 1-9
3. Lee H.W., and Chang S.E. Hyperkeratosis of the nipple associated with acanthosis nigricans: treatment with topical calcipotriol. J. Am. Acad. Dermatol. 52-3 (2005) 529-530
4. Pentenero M., and Carrozzo M. Oral acanthosis nigricans, tripe palms and sign of Leser-Trélat in a patient with gastric adenocarcinoma. Int. J. Dermatol. 43 (2004) 530-532
5. Schwartz R.A. Acanthosis nigricans. J. Am. Acad. Dermatol. 31 (1994) 1-19
6. Matsuoka L.Y., Wortsman J., and Goldman J. Acanthosis nigricans. Clin. Dermatol. 11 (1993) 21-25
7. Kahn C.R., Flier J.S., Bar R.S., Arecher J.A., Gordon P., Martin M.M., et al. The syndromes of insulin resistance and acanthosis nigricans: insulin receptor disorder in man. N. Engl. J. Med. 294 (1976) 739-745
8. Schwartz R.A. Acanthosis nigricans, florid cutaneous paplillomatosis and the sign of Leser-Tre'lat. Cutis 28 (1981) 319-325
9. Breathnach S.M., and Wells G.C. Acanthosis palmaris: tripe palms. A distinctive pattern of palmar keratoderma frequently associated with internal malignancy. Clin. Exp. Dermatol. 5 (1980) 181-189
10. Cohen P.R., Grossman M.E., Almeida L., and Kurzrock R. Tripe palms and malignancy. J. Clin. Oncol. 7 5 (1989) 669-678
11. Cohen P.R., Grossman M.E., Silver D.N., and Kurzrock R. Tripe palms and cancer. Clin. Dermatol. 11 (1993) 165-173
12. Ellis D.L., and Yates R.A. Sign of Leser-Trelat. Clin. Dermatol. 11 (1993) 141-148
13. Schwartz R.A. Sign of Leser-Trélat. J. Am. Acad. Dermatol. 35 (1996) 88-95
14. Gorisek B., and Krajnc I. Case report: malignant acanthosis nigricans and tripe palms in a patient with endometrial adenocarcinoma-A case report and review of literature. Gynecol. Oncol. 65 (1997) 539-542
15. Curth-Ollendorff H., Hilberg A.W., and Machacek G.F. The site and histology of the cancers associated with acanthosis nigricans. Cancer 15 (1962) 364-382
16. Badawi R.A., and Birns J. Acanthosis nigricans associated with acute myeloid leukaemia. Eur. J. Int. Med. 15 7 (2004) 473
17. Hrenschlager M.M., Vocks E., et al. Tripe palms and malignant acanthosis nigricans: cutaneous signs of imminent metastasis in bladder cancer. J. Urol. 165 (2001) 1629-1630
18. Hiranandani M., Kaur I., et al. Malignant acanthosis nigricans in adrenal carcinoma. Indian Pediatr. 32 8 (1995) 920-923
19. Ravnborg L., and Thomsen K. Acanthosis nigricans and bile duct malignancy. Acta Derm. Venereol. 73 5 (1993) 378-379
20. Janier M., Blanchet-Bardon C., et al. Malignant acanthosis nigricans associated with non-Hodgkin's lymphoma. Report of 2 cases. Dermatologica 176 3 (1988) 133-137
21. Garrott T.C. Malignant acanthosis nigricans associated with osteogenic sarcoma. Arch. Dermatol. 106 3 (1972) 384-385
22. Curth H.O. Cancer associated acanthosis nigricans: review of the literature and report of a case of acanthosis nigricans with cancer of the breast. Arch. Surg. 47 (1943) 517-552
23. Curth H.O., Tovell H.M., and Janovski N. Malignant acanthosis nigricans associated with endometrial adenocarcinoma. Bull Sloane Hosp. Wom. NY 8 (1962) 141-146
24. Gorisek B., Krajnc I., Rems D., and Kuheli J. Malignant acanthosis nigricans and tripe palms in a patient with endometrial adenocarcinoma-A case report and review of the literature. Gynecol. Oncol. 65 (1997) 539-542
25. Mikhail G.R., Fachnie D.M., Drukker B.H., Farah R., and Allen H.M. Generalized malignant acanthosis nigricans. Arch. Dermatol. 115 2 (1979) 201-202
26. Gross G., Pfister B., Hellenthal B., and Hagedorn M. Acanthosis nigricans maligna. Dermatologica 168 (1984) 265-272
27. Mekhail T.M., and Markman M. Acanthosis nigricans with endometrial carcinoma: case report and review of the literature. Gynecol. Oncol. 84 2 (2002 (Feb.)) 332-334
28. Dawe C.J., Banfield W.G., and Morgan W.D. Growth in continuous culture, and in hamsters, of cells from a neoplasm associated with acanthosis nigricans. J. Natl. Cancer Inst. 33 (1964) 441-456
29. Ellis D.L., Kaka S.P., Chow J.C., et al. Melanoma, growth factors, acanthosis nigricans, the sign of Leser-Trelat, and multiple acrocondrons: a possible role for alpha transforming growth factor in cutaneous paraneoplastic syndromes. N. Engl. J. Med. 317 (1987) 1582-1587
30. Koyoma S., Ikeda K., et al. Transforming growth factor-alpha (TGF alpha)-producing gastric carcinoma with acanthosis nigricans: an endocrine effect of TGF alpha in the pathogenesis of cutaneous paraneoplastic syndrome and epithelial hyperplasia of the esophagus. J. Gastroenterol. 32 1 (1997) 71-77
31. Cohen P.R., Grossman M.E., Almeida L., and Kurzrock R. Tripe palms and malignancy. J. Clin. Oncol. 7 (1989) 669-678
32. Anderson S.H., et al. Malignant acanthosis nigricans: potential role of chemotherapy. Br. J. Dermatol. 141 4 (1999) 714-716
33. Requena L., Aguilar A., et al. Tripe palms: a cutaneous marker of internal malignancy. J. Dermatol. 22 7 (1995 (Jul.)) 492-495