메뉴 건너뛰기




Volumn 11, Issue 4, 2006, Pages 573-579

Spironolactone induces apoptosis in human mononuclear cells. Association between apoptosis and cytokine suppression

Author keywords

Anti inflammatory drugs; Apoptosis; Cytokines; Human mononuclear cells; Spironolactone; Spironolactone analogues (R203602; POD17 0175; POD07 0854; 1N 11448 and 1N 28123); Steroid hormones

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; SPIRONOLACTONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 33646417666     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-4919-3     Document Type: Article
Times cited : (9)

References (20)
  • 2
    • 0141539404 scopus 로고    scopus 로고
    • Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis
    • Bendtzen K, Hansen PR, Rieneck K. Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis. Clin Exp Immunol 2003; 134: 151-158.
    • (2003) Clin Exp Immunol , vol.134 , pp. 151-158
    • Bendtzen, K.1    Hansen, P.R.2    Rieneck, K.3
  • 3
    • 1542272535 scopus 로고    scopus 로고
    • Spironolactone inhibits production of proinflammatory cytokines by human mononuclear cells
    • Hansen PR, Rieneck K, Bendtzen K. Spironolactone inhibits production of proinflammatory cytokines by human mononuclear cells. Immunol Lett 2004; 91: 87-91.
    • (2004) Immunol Lett , vol.91 , pp. 87-91
    • Hansen, P.R.1    Rieneck, K.2    Bendtzen, K.3
  • 4
    • 0024477650 scopus 로고
    • Spironolactone metabolism: Steady-state serum levels of the sulfur-containing metabolites
    • Gardiner P, Schrode K, Quinlan D, et al. Spironolactone metabolism: Steady-state serum levels of the sulfur-containing metabolites. J Clin Pharmacol 1989; 29: 342-347.
    • (1989) J Clin Pharmacol , vol.29 , pp. 342-347
    • Gardiner, P.1    Schrode, K.2    Quinlan, D.3
  • 5
    • 0030176429 scopus 로고    scopus 로고
    • Simultaneous determination of spironolactone and its metabolites in human plasma
    • Jankowski A, Skorek-Jankowska A, Lamparczyk H. Simultaneous determination of spironolactone and its metabolites in human plasma. J Pharm Biomed Anal 1996; 14: 1359-1365.
    • (1996) J Pharm Biomed Anal , vol.14 , pp. 1359-1365
    • Jankowski, A.1    Skorek-Jankowska, A.2    Lamparczyk, H.3
  • 6
    • 0037908647 scopus 로고    scopus 로고
    • Apoptosis: The complex scenario for a silent cell death
    • Bohm I, Schild H. Apoptosis: The complex scenario for a silent cell death. Mol Imaging Biol 2003; 5: 2-14.
    • (2003) Mol Imaging Biol , vol.5 , pp. 2-14
    • Bohm, I.1    Schild, H.2
  • 7
    • 0036170701 scopus 로고    scopus 로고
    • Process of apoptosis induced by TNF-alpha in murine fibroblast Ltk-cells: Continuous observation with video enhanced contrast microscopy
    • Okamoto K, Mizuno M, Nakahara N, et al. Process of apoptosis induced by TNF-alpha in murine fibroblast Ltk-cells: Continuous observation with video enhanced contrast microscopy. Apoptosis 2002; 7: 77-86.
    • (2002) Apoptosis , vol.7 , pp. 77-86
    • Okamoto, K.1    Mizuno, M.2    Nakahara, N.3
  • 8
    • 0038723231 scopus 로고    scopus 로고
    • "Recruitment signals" from apoptotic cells: Invitation to a quiet meal
    • Ravichandran KS. "Recruitment signals" from apoptotic cells: Invitation to a quiet meal. Cell 2003; 113: 817-820.
    • (2003) Cell , vol.113 , pp. 817-820
    • Ravichandran, K.S.1
  • 10
    • 0024595042 scopus 로고
    • Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
    • Hansen MB, Nielsen SE, Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 1989; 119: 203-210.
    • (1989) J Immunol Methods , vol.119 , pp. 203-210
    • Hansen, M.B.1    Nielsen, S.E.2    Berg, K.3
  • 11
    • 0033989435 scopus 로고    scopus 로고
    • Production of interleukin (IL)-1beta, IL-1 receptor antagonist and IL-10 by blood mononuclear cells in chronic arthritis
    • Andersen LS, Petersen J, Bendtzen K. Production of interleukin (IL)-1beta, IL-1 receptor antagonist and IL-10 by blood mononuclear cells in chronic arthritis. Cytokine 2000; 12: 62-68.
    • (2000) Cytokine , vol.12 , pp. 62-68
    • Andersen, L.S.1    Petersen, J.2    Bendtzen, K.3
  • 12
    • 0035678637 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha (TNF), lymphotoxin and TNF receptor levels in serum from patients with Wegener's granulomatosis
    • Jonasdottir O, Petersen J, Bendtzen K. Tumour necrosis factor-alpha (TNF), lymphotoxin and TNF receptor levels in serum from patients with Wegener's granulomatosis. APMIS 2001; 109: 781-786.
    • (2001) APMIS , vol.109 , pp. 781-786
    • Jonasdottir, O.1    Petersen, J.2    Bendtzen, K.3
  • 14
    • 0141539404 scopus 로고    scopus 로고
    • Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis
    • Bendtzen K, Hansen PR, Rieneck K. Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis. Clin Exp Immunol 2003; 134: 151-158.
    • (2003) Clin Exp Immunol , vol.134 , pp. 151-158
    • Bendtzen, K.1    Hansen, P.R.2    Rieneck, K.3
  • 15
    • 1542272535 scopus 로고    scopus 로고
    • Spironolactone inhibits production of proinflammatory cytokines by human mononuclear cells
    • Hansen PR, Rieneck K, Bendtzen K. Spironolactone inhibits production of proinflammatory cytokines by human mononuclear cells. Immunol Lett 2004; 91: 87-91.
    • (2004) Immunol Lett , vol.91 , pp. 87-91
    • Hansen, P.R.1    Rieneck, K.2    Bendtzen, K.3
  • 16
    • 0025255629 scopus 로고
    • A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence
    • Rubartelli A, Cozzolino F, Talio M, Sitia R. A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence. EMBO J 1990; 9: 1503-1510.
    • (1990) EMBO J , vol.9 , pp. 1503-1510
    • Rubartelli, A.1    Cozzolino, F.2    Talio, M.3    Sitia, R.4
  • 17
    • 0025996804 scopus 로고
    • Release of IL-1 from mononuclear phagocytes
    • Hogquist KA, Unanue ER, Chaplin DD. Release of IL-1 from mononuclear phagocytes. J Immunol 1991; 147: 2181-2186.
    • (1991) J Immunol , vol.147 , pp. 2181-2186
    • Hogquist, K.A.1    Unanue, E.R.2    Chaplin, D.D.3
  • 18
    • 0026828978 scopus 로고
    • Effects of human anti-IL-1 alpha autoantibodies on receptor binding and biological activities of IL-1
    • Svenson M, Hansen MB, Kayser L, Rasmussen AK, Reimert CM, Bendtzen K. Effects of human anti-IL-1 alpha autoantibodies on receptor binding and biological activities of IL-1. Cytokine 1992; 4: 125-133.
    • (1992) Cytokine , vol.4 , pp. 125-133
    • Svenson, M.1    Hansen, M.B.2    Kayser, L.3    Rasmussen, A.K.4    Reimert, C.M.5    Bendtzen, K.6
  • 19
    • 3142660196 scopus 로고    scopus 로고
    • IL-1beta: An endosomal exit
    • Wewers MD. IL-1beta: An endosomal exit. Proc Natl Acad Sci USA 2004; 101: 10241-10242.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10241-10242
    • Wewers, M.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.