Defining the appropriate radiotherapy regimen for metastatic spinal cord compression in non-small cell lung cancer patients

European Journal of Cancer

Volumn 42, Issue 8, 2006, Pages 1052-1056

  Rades, Dirk ^a   Stalpers, Lukas J A ^b   Schulte, Rainer ^c   Veninga, Theo ^d   Basic, Hiba ^e   Engenhart Cabilic, Rita ^f   Schild, Steven E ^g   Hoskin, Peter J ^h  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b Trop Med AIDS E0127 Acad M   (Netherlands)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d DR BERNARD VERBEETEN INSTITUTE   (Netherlands)

^e University Hospital   (Bosnia and Herzegovina)

^f PHILIPPS UNIVERSITY MARBURG   (Germany)

^g MAYO CLINIC   (United States)

^h MOUNT VERNON CANCER CENTRE   (United Kingdom)

Author keywords

Metastatic spinal cord compression; Non small cell lung cancer; Radiotherapy

Indexed keywords

ADULT; ARTICLE; CANCER RADIOTHERAPY; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SPINAL CORD COMPRESSION; SPINAL CORD METASTASIS;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; COHORT STUDIES; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; RADIOTHERAPY DOSAGE; RETROSPECTIVE STUDIES; SPINAL CORD COMPRESSION; SPINAL CORD NEOPLASMS; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 33646406281     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2005.12.022     Document Type: Article

References (16)

1. Poortmans P., Vulto A., and Raaijmakers E. Always on a Friday? Time pattern of referral for spinal cord compression. Acta Oncol 40 (2001) 88-91
2. Patchell R., Tibbs P.A., Regine W.F., et al. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet 366 (2005) 643-648
3. Maranzano E., and Latini P. Effectiveness of radiation therapy without surgery in metastatic spinal cord compression: final results from a prospective trial. Int J Radiat Oncol Biol Phys 32 (1995) 959-967
4. Sørensen P.S., Børgesen S.E., Rohde K., et al. Metastatic epidural spinal cord compression. Cancer 65 (1990) 1502-1508
5. Hoskin P.J., Grover A., and Bhana R. Metastatic spinal cord compression: radiotherapy outcome and dose fractionation. Radiother Oncol 68 (2003) 175-180
6. Sioutos P.J., Arbit E., Meshulam C.F., and Galicich J.H. Spinal metastases from solid tumours. Analysis of factors affecting survival. Cancer 76 (1995) 1453-1459
7. Tatsui H., Onomura T., Morishita S., Oketa M., and Inoue T. Survival rates of patients with metastatic spinal cancer after scintigraphic detection of abnormal radioactive accumulation. Spine 21 (1996) 2143-2148
8. Van der Linden Y.M., Dijkstra S.P.D.S., Vonk E.J.A., et al. Prediction of survival in patients with metastases in the spinal column. Cancer 103 (2004) 320-328
9. Prasad D., and Schiff D. Malignant spinal cord compression. Lancet Oncol 6 (2005) 15-24
10. Tomita T., Galicich J.H., and Sundaresan N. Radiation therapy for spinal epidural metastases with complete block. Acta Radiol Oncol 22 (1983) 135-143
11. Maranzano E., Latini P., Beneventi S., et al. Comparison of two different radiotherapy schedules for spinal cord compression in prostate cancer. Tumouri 84 (1998) 472-477
12. Maranzano E., Bellavita R., Rossi R., et al. Short-course versus split-course radiotherapy in metastatic spinal cord compression: results of a phase III, randomized, multicenter trial. J Clin Oncol 23 (2005) 3358-3365
13. Rades D., Stalpers L.J.A., Veninga T., et al. Evaluation of five radiation schedules and prognostic factors for metastatic spinal cord compression. J Clin Oncol 23 (2005) 3366-3375
14. Rades D., Heidenreich F., and Karstens J.H. Final results of a prospective study for the prognostic value of the time of developing motor deficits before irradiation in metastatic spinal cord compression. Int J Radiat Oncol Biol Phys 53 (2002) 975-979
15. Manabe S., Tanaka H., Higo Y., Park P., Ohno T., and Tateishi A. Experimental analysis of the spinal cord compressed by spinal metastasis. Spine 14 (1989) 1308-1315
16. Emami B., Lyman J., Brown A., et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 21 (1991) 109-122