Dose selection for radioiodine therapy of borderline hyperthyroid patients according to thyroid uptake of 99mTc-pertechnetate: Applicability to unifocal thyroid autonomy?

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 33, Issue 5, 2006, Pages 608-612

  Reinhardt, Michael J ^a,b   Biermann, Kim ^a   Wissmeyer, Michael ^c   Juengling, Freimut D ^b,c   Brockmann, Holger ^a   Von Mallek, Dirk ^a   Ezziddin, Samer ^a   Joe, Alexius Y ^a,b   Krause, Thomas M ^b,c  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Dose calculation; Radioiodine therapy; Unifocal thyroid autonomy

Indexed keywords

LEVOTHYROXINE; PERTECHNETIC ACID TC 99M; RADIOACTIVE IODINE; THYROTROPIN;

ADULT; AGED; ARTICLE; BORDERLINE HYPERTHYROIDISM; DEVICE; DOSE CALCULATION; DRUG DOSE REGIMEN; DRUG UPTAKE; ECHOGRAPHY; EUTHYROIDISM; FEASIBILITY STUDY; FEMALE; HUMAN; HYPERTHYROIDISM; HYPOTHYROIDISM; MAJOR CLINICAL STUDY; MALE; RADIATION DOSE; RADIOISOTOPE THERAPY; SCINTIGRAPHY; SCINTILLATION CAMERA; THYROID DISEASE; THYROID GLAND; THYROID NODULE; THYROTROPIN BLOOD LEVEL; THYROTROPIN RELEASE; THYROTROPIN SUPPRESSION; UNIFOCAL THYROID ANOMALY;

ADULT; AGED; AGED, 80 AND OVER; DOSE FRACTIONATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEASIBILITY STUDIES; FEMALE; HUMANS; HYPERTHYROIDISM; IODINE RADIOISOTOPES; MALE; MIDDLE AGED; PROGNOSIS; RADIOPHARMACEUTICALS; RADIOTHERAPY DOSAGE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SODIUM PERTECHNETATE TC 99M; TREATMENT OUTCOME;

EID: 33646405482     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-005-0051-9     Document Type: Article

References (14)

1. 99mTc-pertechnetate thyroid uptake. Eur J Nucl Med Mol Imaging 2002;29:480-485
2. 99mTc pertechnetate. Acta Endocrinol (Copenh) 1987;115:175-182
3. Emrich D, Erlenmaier U, Pohl M, Luig H. Determination of the autonomously functioning volume of the thyroid. Eur J Nucl Med 1993;20:410-414
4. Miller JM, Horn RC, Block MA. The autonomous functioning thyroid nodule in the evolution of nodular goiter. J Clin Endocrinol Metab 1967;27:1264-1274
5. Ramelli F, Studer H, Bruggisser D. Pathogenesis of thyroid nodules in multinodular goiter. Am J Pathol 1982;109:215-223
6. Studer H, Ramelli F. Simple goiter and its variants: euthyroid and hyperthyroid multinodular goiters. Endocr Rev 1982;3:40-61
7. Peter HJ, Gerber H, Studer H, Smeds S. Pathogenesis of heterogeneity in human multinodular goiter. A study on growth and function of thyroid tissue transplanted onto nude mice. J Clin Invest 1985;76:1992-2002
8. Studer H, Peter HJ, Gerber H. Natural heterogeneity of thyroid cells: the basis for understanding thyroid function and nodular goiter growth. Endocr Rev 1989;10:125-135
9. Studer H, Peter HJ, Gerber H. Morphologic and functional changes in developing goiters. In: Hall R, Köbberling J, eds. Thyroid disorders associated with iodine deficiency and excess. New York: Raven Press; 1985; p.227-241
10. Brunn J, Block U, Ruf G, Bos I, Kunze WP, Scriba PC. Volumetric analysis of thyroid lobes by real-time ultrasound. Deut Med Wochenschr 1981;106:1338-1340
11. 99mTc-thyroid uptake test in thyroid diagnostics. Nuc Compact 1981;12:37-40
12. Marinelli LD, Quinby EH, Hine GJ. Dosage determination with radioactive isotopes. Practical considerations in therapy and protection. Am J Roentgenol 1948;59:260-281
13. s-optimized radioiodine therapy of multifocal and disseminated functional thyroid autonomy. Nuklearmedizin 1999;38:131-139
14. Meller J, Wisheu S, Munzel U, Behe M, Gratz S, Becker W. Radioiodine therapy for Plummer's disease based on the thyroid uptake of technetium-99 m pertechnetate. Eur J Nucl Med 2000;27:1286-1291