Comparison of antitumor effect between brucine and its liposome in mice transplanted with tumor in vivo

Chinese Traditional and Herbal Drugs

Volumn 37, Issue 3, 2006, Pages 389-393

  Deng, Xu Kun ^a,c   Cai, Bao Chang ^a   Lü, Xiao Yu ^a   Yin, Wu ^b   Wang, Lin ^a   Zhang, Xiao Chun ^a   Liu, Tao Shi ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b NANJING UNIVERSITY   (China)

^c SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES   (China)

Author keywords

Antitumor activity; Brucine; Liposome; Mice with transplanted tumor

Indexed keywords

BRUCINE; LIPOSOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER SURVIVAL; CANCER TRANSPLANTATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; GROWTH INHIBITION; IN VIVO STUDY; INOCULATION; MOUSE; NONHUMAN; SURVIVAL TIME;

EID: 33646359438     PISSN: 02532670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. 13C-NMR of sixteen Strychnos alkaloids [J]. Acta Pharm Sin 1994, 29(1): 44-48.
2. Cai B C, Wang T S, Masahiko K, et al. Cytotoxicities of alkaloids from processed and unprocessed seeds of Strychnos nui-vomica [J]. Acta Pharmacol Sin 1998, 19(5): 425-428.
3. Cai B C, Chen L, Namba T. Processing nux vomica IV. A comparison of nine alkaloids from processed seeds of Strychnos nux-vomica on tumor cell lines [J]. Nat Med, 1995, 49 (1): 39-42.
4. Chen L, Cai B C, Lu Y M, et al. A comparsion between brucine and isobrucine N-oxide on cytotoxicity on tumor cell and anti-oxidative damage action [J]. J Nanjing Univ Tradit Chin Med 1998, 14(6): 349-351.
5. Sihorkar Vyas S P. Potential of polysaccharide anchored liposomes in drug delivery, targeting, and immunization [J]. J Pharm Sci, 2001, 4(2): 138-158.
6. Budai M, Szogyi M. Liposomes as drug carrier systems. Preparation, classification, and therapeutic advantages of liposomes [J]. Acta Pharm Hung, 2001, 71(1): 114-118.
7. Wang J S, Zhu J B. Preparation of azithromycin liposome and its entrapment efficiency determination [J]. J China Pharm Univ 2004, 35(6): 499-502.
8. Zhang J, Yang J, Wu J L, et al. Preparation of isoliquiritigenin liposome and its inhibitive effects on proliferation of human cervical cancer cells in vitro [J]. Chin J Clin Pharmacol Ther 2004, 9(11): 1268-1272.
9. Liu J W, Ji G, Wei D Z. Pharmacology of Experimental Method - New Technology and Methodology [M]. Beijing: Chemical Industry Press, 2003.
10. Cheng L, Zhou X J. Review on anticancer mechanism of some plant alkaloid [J]. Chin Tradit Herb Drug 2004, 35(2): 216-221.
11. Leanne E, Karen A G, Andreas L, et al. Chromatographic analysis and pharmacokinetics of liposome-encapsulated doxorubicin in non-small cell lung cancer patients [J]. J Pharm Sci, 1993, 82: 627.
12. Lu Q Z, Zhang C. Pharmacokinetics of fluoroful temperature-sensitive liposome in rabbits [J]. Acad J Sec Mil Med Univ 2002, 23(11): 1227-1229.
13. Yin W, Wang T S, Yin F Z, et al. Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica [J]. EUR J Ethnopharmacol, 2003, 88(3-4): 205-214.