Modification of a mammalian cell protein in the presence of [ 32P-adenylate]NAD: Evidence for ADP ribosylation activity associated with Helicobacter pylori

Infection and Immunity

Volumn 74, Issue 5, 2006, Pages 3071-3076

  Nossa, Carlos W ^b   Blanke, Steven R ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHORUS 32;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ANIMAL CELL; ARTICLE; BACTERIUM CULTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; ISOTOPE LABELING; MAMMAL CELL; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN TARGETING; STRAIN IDENTIFICATION; THERMOSTABILITY;

ADP RIBOSE TRANSFERASES; HELA CELLS; HELICOBACTER PYLORI; HUMANS; NAD; PHOSPHORUS RADIOISOTOPES; PROTEINS;

EID: 33646340663     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.74.5.3071-3076.2006     Document Type: Article

References (29)

1. Barbieri, J. T., and D. L. Burns. 2003. Bacterial toxins that covalently modify eukaryotic proteins by ADP ribosylation, p. 215-228. In D. L. Burns, J. T. Barbieri, B. H. Iglewski, and R. Rappuoli (ed.), Bacterial protein toxins. ASM Press, Washington, D.C.
2. Barbieri, J. T., L. M. Mende-Mueller, R. Rappuoli, and R. J. Collier. 1989. Photolabeling of Glu-129 of the S-1 subunit of pertussis toxin with NAD. Infect. Immun. 57:3549-3554.
3. Blanke, S. R. 2005. Micro-managing the executioner: pathogen targeting of mitochondria. Trends Microbiol. 13:64-71.
4. Blaser, M. J. 2005. The biology of cag in the Helicobacter pylori-human interaction. Gastroenterology 128:1512-1515.
5. Blaser, M. J., and J. C. Atherton. 2004. Helicobacter pylori persistence: biology and disease. J. Clin. Investig. 113:321-333.
6. Blaser, M. J., and D. E. Berg. 2001. Helicobacter pylori genetic diversity and risk of human disease. J. Clin. Investig. 107:767-773.
7. Cao, P., M. S. McClain, M. H. Forsyth, and T. L. Cover. 1998. Extracellular release of antigenic proteins by Helicobacter pylon. Infect. Immun. 66:2984-2986.
8. Carroll, S. F., and R. J. Collier. 1984. NAD binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD. Proc. Natl. Acad. Sci. USA 81:3307-3311.
9. Carroll, S. F., J. A. McCloskey, P. F. Crain, N. J. Oppenheimer, T. M. Marschner, and R. J. Collier. 1985. Photoaffinity labeling of diphtheria toxin fragment A with NAD: structure of the photoproduct at position 148. Proc. Natl. Acad. Sci. USA 82:7237-7241.
10. Cover, T. L., and S. R. Blanke. 2005. Helicobacter pylori VacA, a paradigm for toxin multifunctionality. Nat. Rev. Microbiol. 3:320-332.
11. Cover, T. L., and M. J. Blaser. 1999. Helicobacter pylori factors associated with disease. Gastroenterology 117:257-261.
12. Cover, T. L., and M. J. Blaser. 1992. Purification and characterization of the vacuolating toxin from Helicobacter pylori. J. Biol. Chem. 267:10570-10575.
13. Domenighini, M., and R. Rappuoli. 1996. Three conserved consensus sequences identify the NAD-binding site of ADP-ribosylating enzymes, expressed by eukaryotes, bacteria and T-even bacteriophages. Mol. Microbiol. 21:667-674.
14. Graham, D. Y., G. M. Lew, P. D. Klein, D. G. Evans, D. J. Evans, Jr., Z. A. Saeed, and H. M. Malaty. 1992. Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study. Ann. Intern. Med. 116:705-708.
15. Leunk, R. D., P. T. Johnson, B. C. David, W. G. Kraft, and D. R. Morgan. 1988. Cytotoxic activity in broth-culture filtrates of Campylobacter pylori. J. Med. Microbiol. 26:93-99.
16. Marburg, S., R. L. Tolman, and L. T. Callahan III. 1983. Pseudomonas exotoxin A: toxoid preparation by photoaffinity inactivation. Proc. Natl. Acad. Sci. USA 80:2870-2873.
17. Marshall, B. J., C. S. Goodwill, J. R. Warren, R. Murray, E. D. Blincow, S. J. Blackbourn, M. Phillips, T. E. Waters, and C. R. Sanderson. 1988. Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori. Lancet ii:1437-1442.
18. McGee, D. J., and H. L. Mobley. 1999. Mechanisms of Helicobacter pylori infection: bacterial factors. Curr. Top. Microbiol. Immunol. 241:155-180.
19. Medical and Chirurgical Faculty of the State of Maryland. 1994. Summary of the NIH consensus. Helicobacter pylori in peptic ulcer disease. Md. Med. J. 43:923-924.
20. Moss, S. F., and M. J. Blaser. 2005. Mechanisms of disease: inflammation and the origins of cancer. Nat. Clin. Pract. Oncol. 2:90-97.
21. Nomura, A., G. N. Stemmermann, P. H. Chyou, I. Kato, G. I. Perez-Perez, and M. J. Blaser. 1991. Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. N. Engl. J. Med. 325:1132-1136.
22. Odenbreit, S., J. Puls, B. Sedlmaier, E. Gerland, W. Fischer, and R. Haas. 2000. Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science 287:1497-1500.
23. Parsonnet, J., G. D. Friedman, D. P. Vandersteen, Y. Chang, J. H. Vogelman, N. Orentreich, and R. K. Sibley. 1991. Helicobacter pylori infection and the risk of gastric carcinoma. N. Engl. J. Med. 325:1127-1131.
24. Parsonnet, J., S. Hansen, L. Rodriguez, A. B. Gelb, R. A. Warnke, E. Jellum, N. Orentreich, J. H. Vogelman, and G. D. Friedman. 1994. Helicobacter pylori infection and gastric lymphoma. N. Engl. J. Med. 330:1267-1271.
25. Pizza, M., V. Masignani, and R. Rappuoli. 1999. Molecular, functional, and evolutionary aspects of ADP-ribosylating toxins, p. 45-72. In J. E. Alouf and J. H. Freer, The comprehensive sourcebook of bacterial protein toxins, 2nd ed. Academic Press, London, United Kingdom.
26. Sachs, G., D. L. Weeks, K. Melchers, and D. R. Scott. 2003. The gastric biology of Helicobacter pylori. Annu. Rev. Physiol. 65:349-369.
27. Schraw, W., M. S. McClain, and T. L. Cover. 1999. Kinetics and mechanisms of extracellular protein release by Helicobacter pylori. Infect. Immun. 67:5247-5252.
28. Stingl, K., K. Altendorf, and E. P. Bakker. 2002. Acid survival of Helicobacter pylori: how does urease activity trigger cytoplasmic pH homeostasis? Trends Microbiol. 10:70-74.
29. Wotherspoon, A. C., C. Doglioni, T. C. Diss, L. Pan, A. Moschini, M. de Boni, and P. G. Isaacson. 1993. Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet 342:575-577.