Prednisone withdrawal in pediatric kidney transplant recipients on tacrolimus-based immunosuppression: Four-year data

Pediatric Transplantation

Volumn 10, Issue 3, 2006, Pages 337-344

  Hamiwka, Lorraine A ^a   Burns, Angela ^b   Bell, Lorraine ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b MONTREAL CHILDREN S HOSPITAL   (Canada)

Author keywords

Children; Immunosuppression; Kidney transplantation; Prednisone withdrawal; Tacrolimus

Indexed keywords

AZATHIOPRINE; CREATININE; CYTOMEGALOVIRUS ANTIBODY; DACLIZUMAB; GANCICLOVIR; LIPID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; TACROLIMUS; THYMOCYTE ANTIBODY;

ACNE; ACUTE GRAFT REJECTION; ADULT; BARTTER SYNDROME; BLOOD PRESSURE; BODY MASS; CATCH UP GROWTH; CLINICAL ARTICLE; CONGENITAL NEPHROTIC SYNDROME; CORTICOSTEROID THERAPY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; CYSTINOSIS; CYTOMEGALOVIRUS INFECTION; DEMOGRAPHY; DRASH SYNDROME; DRUG HYPERSENSITIVITY; DRUG WITHDRAWAL; EPSTEIN BARR VIRUS; FEMALE; FOLLOW UP; GLOMERULONEPHRITIS; GRAFT SURVIVAL; GROWTH RETARDATION; HEMOLYTIC UREMIC SYNDROME; HLA MATCHING; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KAPLAN MEIER METHOD; KIDNEY CORTEX NECROSIS; KIDNEY DYSPLASIA; KIDNEY FAILURE; KIDNEY POLYCYSTIC DISEASE; KIDNEY TRANSPLANTATION; LIPID BLOOD LEVEL; LOW DRUG DOSE; MAINTENANCE THERAPY; MALE; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; NEUTROPENIA; OBSTRUCTIVE UROPATHY; PATIENT COMPLIANCE; REVIEW; STATISTICAL ANALYSIS; VESICOURETERAL REFLUX; VIRUS INFECTION; WEIGHT GAIN;

ADOLESCENT; ADULT; AZATHIOPRINE; CHILD; CHILD, PRESCHOOL; CREATININE; FEMALE; HUMANS; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; INFANT; KIDNEY TRANSPLANTATION; MALE; PREDNISONE; STEROIDS; TACROLIMUS; TIME FACTORS;

EID: 33646269736     PISSN: 13973142     EISSN: 13993046     Source Type: Journal    
DOI: 10.1111/j.1399-3046.2005.00476.x     Document Type: Review

References (46)

1. Harmon WE McDonald RA Reyes JD et al Pediatric transplantation, 1994-2003 Am J Transplant 2005 5 887 903
2. Veenstra DL Best JH Hornberger J Sullivan S Hricik DE Incidence and long-tem cost of steroid-related side effects after renal transplantation Am J Kidney Dis 1999 33 829 839
3. Pascual M Theruvath T Kawai T Tolkoff-Rubin N Cosimi AB Strategies to improve long-term outcomes after renal transplantation N Engl J Med 2002 346 580 590
4. Hricik DE Steroid withdrawal in renal transplant recipients pro point of view Transplant Proc 1998 30 1380 1382
5. Fine RN Growth following solid-organ transplantation Pediatr Transplantation 2002 6 47 52
6. Klaus G Jeck N Konrad M Forster B Soergel M Risk of steroid withdrawal in pediatric renal transplant patients with suspected steroid toxicity Clin Nephrol 2001 56 S37 S42
7. Dunn TB Asolati M Holman DM et al Long-term outcome of a prospective trial of steroid withdrawal after kidney transplantation Surgery 1999 125 155 159
8. Ratcliffe PJ Dudley CR Higgins RM Firth JD Smith B Morris PJ Randomised controlled trial of steroid withdrawal in renal transplant recipients receiving triple immunosuppression Lancet 1996 348 643 648
9. Roberti I Reisman L Lieberman KV Burrows L Risk of steroid withdrawal in pediatric renal allograft recipients (a 5-year follow-up) Clin Transplantation 1994 8 405 408
10. Sinclair NR Low-dose steroid therapy in cyclosporine-treated renal transplant recipients with well-functioning grafts. The Canadian Multicentre Transplant Study Group CMAJ 1992 147 645 657
11. Kasiske BL Chakkera HA Louis TA Ma JZ A meta-analysis of immunosuppression withdrawal trials in renal transplantation J Am Soc Nephrol 2000 11 1910 1917
12. Vanrenterghem Y Lebranchu Y Hene R Oppenheimer F Ekberg H for the Steroid Dosing Study Group. Double-blind comparison of two corticosteroid regimens plus mycophenolate mofetil and cyclosporine for prevention of acute renal allograft rejection Transplantation 2000 70 1352 1359
13. Ahsan N Hricik D Matas A et al Prednisone withdrawal in kidney transplant recipients on cyclosporine and mycophenolate mofetil - a prospective randomized study. Steroid Withdrawal Study Group Transplantation 1999 68 1865 1874
14. Gonin JM Maintenance immunosuppression new agents and persistent dilemmas Adv Renal Replacement Therapy 2000 7 95 116
15. Hricik DE Steroid-free immunosuppression in kidney transplantation an editorial review Am J Transplant 2002 2 19 24
16. Hocker B John U Plank C et al Successful withdrawal of steroids in pediatric renal transplant recipients receiving cyclosporine A and mycophenolate mofetil treatment results after four years Transplantation 2004 78 228 234
17. Shapiro R Scantlebury VP Jordan ML et al Tacrolimus in pediatric renal transplantation Transplantation 1996 62 1752 1758
18. Shapiro R Scantlebury VP Jordan ML et al Pediatric renal transplantation under tacrolimus-based immunosuppression Transplantation 1999 67 299 303
19. Chakrabarti P Wong HY Scantlebury VP et al Outcome after steroid withdrawal in pediatric renal transplant patients receiving tacrolimus-based immunosuppression Transplantation 2000 70 760 764
20. Pascual J Quereda C Zamora J Hernandez D Spanish Group for Evidence-Based Medicine in Renal Transplantation. Steroid withdrawal in renal transplant patients on triple therapy with a calcineurin inhibitor and mycophenolate mofetil a meta-analysis of randomized, controlled trials Transplantation 2004 78 1548 1556
21. Schwartz GJ Brion LP Spitzer A The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents Pediatr Clin North Am 1987 34 571 590
22. Hamill PV Drizd TA Johnson CL et al NCHS growth curves for children birth - 18 years. United States. Vital & Health Statistics - Series II data from the National Health Survey 1977 165 1 74
23. National High Blood Pressure Education Program Working Group. Update on the 1987 Task Force Report on High Blood Pressure in Children and Adolescents a working group report from the National High Blood Pressure Education Program Pediatrics 1996 98 649 658
24. Resnicow K Morley-Kotchen J Wynder E Plasma cholesterol levels of 6585 children in the United States results of the know your body screening in five states Pediatrics 1989 84 969 976
25. Lockitch G Halstead AC Albersheim S MacCallum C Quigley G Age- and sex-specific pediatric reference intervals for biochemistry analytes as measured with the Ektachem-700 analyzer Clin Chem 1988 34 1622 1625
26. Kaplan EL Meier P Non parametric estimation from incomplete observations J Am Stat Assoc 1958 53 457 481
27. Reisman L Leiberman KV Burrows L Schanzer H Follow-up of cyclosporine-treated pediatric renal allograft recipients after cessation of prednisone Transplantation 1990 49 76 80
28. Sivaraman P Nussbaumer G Landsberg D Lack of long-term benefits of steroid withdrawal in renal transplant recipients Am J Kidney Dis 2001 37 1162 1169
29. Grinyo JM Gil-Vernet S Seron D et al Steroid withdrawal in mycophenolate mofetil-treated renal allograft recipients Transplantation 1997 63 1688 1690
30. Ahsan N Johnson C Gonwa T et al Randomized trial of tacrolimus plus mycophenolate mofetil or azathioprine versus cyclosporine oral solution (modified) plus mycophenolate mofetil after cadaveric kidney transplantation results at 2 years Transplantation 2001 72 245 250
31. Shapiro R Jordan ML Scantlebury VP et al A prospective, randomized trial of tacrolimus/prednisone versus tacrolimus/prednisone/mycophenolate mofetil in renal transplant recipients Transplantation 1999 67 411 415
32. Cattaneo D Perico N Gaspari F Gotti E Remuzzi G Glucocorticoids interfere with mycophenolate mofetil bioavailability in kidney transplantation Kidney Int 2002 62 1060 1067
33. van Duijnhoven EM Boots JM Christiaans MH Stolk LM Undre NA van Hooff JP Increase in tacrolimus trough levels after steroid withdrawal Transplant Int 2003 16 721 725
34. Ellis D Growth and renal function after steroid-free tacrolimus-based immunosuppression in children with renal transplants Pediatr Nephrol 2000 14 689 694
35. Jensen S Jackson EC Riley L Reddy S Goebel J Tacrolimus-based immunosuppression with steroid withdrawal in pediatric kidney transplantation - 4-year experience at a moderate-volume center Pediatr Transplantation 2003 7 119 124
36. Rocha PN Plumb TJ Miller SE Howell DN Smith SR Risk factors for BK polyomavirus nephritis in renal allograft recipients Clin Transplant 2004 18 456 462
37. Ginevri F De Santis R Comoli P et al Polyomavirus BK infection in pediatric kidney-allograft recipients a single-center analysis of incidence, risk factors, and novel therapeutic approaches Transplantation 2003 75 1266 1270
38. Bustami RT Ojo AO Wolfe RA et al Immunosuppression and the risk of post-transplant malignancy among cadaveric first kidney transplant recipients Am J Transplant 2004 4 87 93
39. Artz MA Boots JM Ligtenberg G et al Improved cardiovascular risk profile and renal function in renal transplant patients after randomized conversion from cyclosporine to tacrolimus J Am Soc Nephrol 2003 14 1880 1888
40. McCune TR Thacker LR Peters TG et al Effects of tacrolimus on hyperlipidemia after successful renal transplantation a Southeastern Organ Procurement Foundation multicenter clinical study Transplantation 1998 65 87 92
41. Boots JM van Duijnhoven EM Christiaans MH Wolffenbuttel BH van Hooff JP Glucose metabolism in renal transplant recipients on tacrolimus the effect of steroid withdrawal and tacrolimus trough level reduction J Am Soc Nephrol 2002 13 221 227
42. Sarwal MM Yorgin PD Alexander S et al Promising early outcomes with a novel, complete steroid avoidance immunosuppression protocol in pediatric renal transplantation Transplantation 2001 72 13 21
43. Cole E Landsberg D Russell D et al A pilot study of steroid-free immunosuppression in the prevention of acute rejection in renal allograft recipients Transplantation 2001 72 845 850
44. Khwaja K Asolati M Harmon J et al Outcome at 3 years with a prednisone-free maintenance regimen a single-center experience with 349 kidney transplant recipients Am J Transplant 2004 4 980 987
45. Hricik DE Whalen CC Lautman J et al Withdrawal of steroids after renal transplantation - clinical predictors of outcome Transplantation 1992 53 41 5
46. Dharnidharka VR Ho PL Stablein DM Harmon WE Tejani AH Mycophenolate, tacrolimus and post transplant lymphoproliferative disorder a report of the North American Pediatric Renal Transplant Cooperative Study Pediatr Transplant 2002 6 396 399