Neutrophil elastase predicts trastuzumab responsiveness in metastatic breast cancer [6]

Breast Journal

Volumn 12, Issue 3, 2006, Pages 288-

  Yamashita, June Ichi ^a   Akizuki, Miwa ^a   Jotsuka, Toko ^a   Harao, Michiko ^a   Nakano, Shogo ^a  

^a AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTASE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GENE PRODUCT; GLYCOPROTEIN E; TRASTUZUMAB;

BREAST CANCER; DRUG RESPONSE; GENE AMPLIFICATION; GENE OVEREXPRESSION; HUMAN; LETTER; MAJOR CLINICAL STUDY; METASTASIS; NEUTROPHIL;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CLINICAL TRIALS; FEMALE; HUMANS; LEUKOCYTE ELASTASE; NEOPLASM METASTASIS; RECEPTOR, ERBB-2;

EID: 33646247627     PISSN: 1075122X     EISSN: 15244741     Source Type: Journal    
DOI: 10.1111/j.1075-122X.2006.00265.x     Document Type: Letter

References (5)

1. Carter P Presta L Gorman CM et al. Humanization of an anti p185HER2 antibody for human cancer therapy Proc Natl Acad Sci USA 1992 89 4285 89
2. Vogel CL Cobleigh MA Tripathy D et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer J Clin Oncol 2002 20 719 26
3. Yamashita J Ogawa M Ikei S et al. Production of immunoreactive polymorphonuclear leukocyte elastase in human breast cancer cells: possible role of polymorphonuclear leukocyte elastase in the progression of human breast cancer Br J Cancer 1994 69 72 76
4. Yamashita J Ogawa M Shirakusa T Free-form neutrophil elastase is an independent marker predicting recurrence in primary breast cancer J Leukocyte Biol 1995 57 375 78
5. DiCamillo SJ Carreras I Panchenko MV et al. Elastase-released epidermal growth factor recruits epidermal growth factor receptor and extracellular signal-regulated kinases to down-regulate tropoelastin mRNA in lung fibroblasts J Biol Chem 2002 277 18938 46