Simultaneous determination of metoprolol tartrate and felodipine in skin diffuse solution by HPLC

Chinese Pharmaceutical Journal

Volumn 41, Issue 2, 2006, Pages 143-146

  Wang, Wen Gang ^a   Yun, Liu Hong ^a   Wang, Rui ^b   Zhou, Xiao Qing ^b  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Felodipine; HPLC; Metoprolol tartrate; Skin permeation

Indexed keywords

ACETIC ACID; FELODIPINE; METHANOL; METOPROLOL TARTRATE; SODIUM 1 HEPTANESULFONATE; SOLVENT; TURPENTINE OIL; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; NONHUMAN; PH; QUANTITATIVE ANALYSIS; RAT; RELIABILITY; REPRODUCIBILITY; SKIN PERMEABILITY; VALIDATION STUDY;

EID: 33646236778     PISSN: 10012494     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. DAHLOF B, HOSIE J. Antihypertensive efficacy and tolerability of a new once-daily felodipine-metoprolol combination compared with each component alone[J]. Blood Press, 1993,2( Suppl 1):22-29.
2. DAHLOF B, JONSSON L, BORGHOLST O, et al. Improved antihypertensive efficacy of the felodipine-metoprolol extended-release tablet compared with each drag alone[J]. Blood Press, 1993,2(Suppl 1):37-45.
3. HOFFMAN J. Comparison of a felodipine-metoprolol tablet vs each component alone as antihypertensive therapy[J]. Blood Press, 1993,2 (Suppl 1):30-36.
4. ABERT J, ABRAHAMSSON B, GRIND M, et al. Bioequivalence, pharmacokinetic and pharmacodynamic response to combined extended release formulations of felodipine and metoprolol in healthy volunteers[J]. Eur J Clin Pharmacol, 1997,52(4):471-477.
5. HUANG B L, WU J, WANG H Q, et al. Determination of metoprolol in serum by reversed-phase high performance liquid chromatography [J]. Chin J Mod Appl Pharm(Chinese character), 2000,17 (5):408-410.
6. ZHANG B K, YUAN H Y, GUO J P, et al. Study on relative bioavailability, pharmacokinetics and pharmacodynamics of metoprolol tartrate tablet[J]. Chin Hosp Pharm J(Chinese character), 2001, 21 (10):589-592.
7. WU Y P, LUO W. Simultaneous determination of propafenone and metoprolol plasma by HPLC[J]. Chin J New Drugs(Chinese character), 2000,9 (2):99-100.
8. QU F J, ZHANG X J, SONG L, et al. Studies on the pharmacokinetics interaction between metoprolol and captopril in healthy volunteers[J]. Chin Pharm J(Chinese character), 2001,36(2):111-113.