Atypical antipsychotic-induced akathiasia with depression: Therapeutic role of mirtazapine

Annals of Pharmacotherapy

Volumn 40, Issue 4, 2006, Pages 771-774

  Ranjan, Sanjeev ^a   Chandra, Prabha S ^a   Chaturvedi, Santosh K ^a   Prabhu, Santosh C ^a   Gupta, Arun ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

Akathisia; Depression; Mirtazapine; Olanzapine; Risperidone

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ATYPICAL ANTIPSYCHOTIC AGENT; DOPAMINE; HISTAMINE H1 RECEPTOR; MIRTAZAPINE; OLANZAPINE; PROPRANOLOL; RISPERIDONE;

ADULT; AKATHISIA; ARTICLE; BIPOLAR DISORDER; BRIEF PSYCHIATRIC RATING SCALE; CLINICAL ARTICLE; CLINICAL FEATURE; COMORBIDITY; DELUSIONAL DISORDER; DEPRESSION; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; FEMALE; GALACTORRHEA; HUMAN; MALE; MEMORY DISORDER; PRIORITY JOURNAL; PROBABILITY; PSYCHIATRIC DIAGNOSIS; SCHIZOPHRENIA; TREATMENT OUTCOME;

ADULT; AKATHISIA, DRUG-INDUCED; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; FEMALE; HUMANS; MALE; MIANSERIN; RISPERIDONE; SEROTONIN ANTAGONISTS; TREATMENT OUTCOME;

EID: 33646231531     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1G561     Document Type: Article

References (23)

1. Citrome L, Volavka J. The promise of atypical antipsychotics: fewer side effects mean enhanced compliance and improved functioning. Postgard Med 2004;116:49-63.
2. Wirshing DA, Marshall BD, Green MF, Mintz J, Marder SR, Wirshing WC. Risperidone in treatment-refractory schizophrenia. Am J Psychiatry 1999;156:1374-9.
3. Malla A, Norman R, Scholten D, et al. A comparison of two novel antipsychotics in first episode non-effective psychosis: one-year outcome on symptoms, motor side effects and cognition. Psychiatry Res 2004;129:159-69. DOI 10.1016/j.psychres.2004.07.008
4. Hiroe S. The causes of underdiagnosing akathisia. Schizophr Bull 2003;29:547-58.
5. Atbasoglu EC, Schultz SK, Andreasen NC. The relationship of akathisia with suicidality and depersonalization among patients with schizophrenia. J Neuropsychiatry Clin Neurosci 2001;13:336-41.
6. Sachdev P, Kruk J. Clinical characteristics and predisposing factors in acute drug-induced akathisia. Arch Gen Psychiatry 1994;51:963-74.
7. Poyurovsky M, Weizman A. Serotonin-based pharmacotherapy for acute neuroleptic-induced akatishia: a new approach to an old problem. Br J Psychiatry 2001;179:4-8.
8. Patten SB, Barbui C. Drug-induced depression: a systematic review to inform clinical practice. Psychother Psychosom 2004;73:207-15.
9. 2 antagonist mianserin. Double-blind, placebo-controlled study. Br J Psychiatry 1999;174:238-42.
10. Lane RM. SSRI induced extrapyramidal side effects and akathisia: implications for treatment. J Psychopharmacol 1998;12:192-214.
11. Fischel T, Hermesh H, Aizenberg D, et al. Cyproheptadine vs propranolol for the treatment of acute neuroleptic-induced akathisia: a comparative double-blind study. J Clin Psychopharmacol 2001;21:612-5.
12. Poyurovsky M, Weizman A. Low dose mirtazapine ameliorates acute neuroleptic-induced akathisia (letter). Am J Psychiatry 2001;158:819.
13. Poyurovsky M, Epshtein S, Fuchs C, Schneidman M, Weizman R, Weizman A. Efficacy of low-dose mirtazapine in neuroleptic-induced akathisia: a double-blind randomized placebo-controlled pilot study. J Clin Psychopharmacol 2003;23:305-8.
14. Naranjo CA, Busto U, Sellers M, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol 1981;30:239-45.
15. 2 receptor occupancy of olanzapine in schizophrenia: a PET investigation. Am J Psychiatry 1998;155:921-8.
16. Meltzer HY. The role of serotonin in antipsychotic drug action. Neuropsychopharmacology 1999;21(suppl 2):106S-15S.
17. Vinson DR. Diphenhydramine in the treatment of akathisia induced by prochlorperazine. J Emerg Med 2004;26:265-70. DOI 10.1016/j.jemermed.2003.11.011
18. Devoto P, Flore G, Pira L, Longu G, Gessa GL. Mirtazapine-induced corelease of dopamine and noradrenaline from noradrenergic neurons in the medial prefrontal and occipital cortex. Eur J Pharmacol 2004;487:105-11. DOI 10.1186/1471-2202-6-31.
19. Wilson MS. Mirtazapine for akathisia in bipolar disorder. J Clin Psychopharmacol 2005;25:394-5.
20. Simpson GM, Flower CJ. Beta adrenergic receptor antagonists. In: Saddock BJ, Saddock VA, eds. Kaplan and Saddock's comprehensive textbook of psychiatry. Philadelphia: Lippincott Williams and Wilkins, 2000:2317-24.
21. Koutouvidis N, Pratikakis M, Fotiadou A. The use of mirtazapine in a group of 11 patients following poor compliance to selective serotonin reuptake inhibitor treatment due to sexual dysfunction. Int Clin Psychopharmacol 1999;14:253-5.
22. Labbate LA, Croft HA, Oleshansky MA. Antidepressant-related erectile dysfunction: management via avoidance, switching antidepressants, antidotes, and adaptation. J Clin Psychiatry 2003;64:11-9.
23. Ballenger JC. Benzodiazepine receptor agonists and antagonists. In: Saddock BJ, Saddock VA, eds. Kaplan and Saddock's comprehensive textbook of psychiatry. Philadelphia: Lippincott Williams and Wilkins, 2000:2271-6.