An alternative paclitaxel self-emulsifying microemulsion formulation: Preparation, pharmacokinetic profile, and evaluation

PDA Journal of Pharmaceutical Science and Technology

Volumn 60, Issue 2, 2006, Pages 89-94

  Zhang, Xue Nong ^a,c   Tang, Li Hua ^a   Gong, Jin Hong ^a   Yan, Xue Ying ^b   Zhang, Qiang ^c  

^a SOOCHOW UNIVERSITY   (China)

^b HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Hypersensitivity; Microemulsion; Paclitaxel; Pharmacokinetics; Self emulsifying emulsification

Indexed keywords

ALCOHOL; EMULSIFYING AGENT; OIL; PACLITAXEL; PHOSPHATIDYLCHOLINE; POLOXAMER; SODIUM CHLORIDE; TRIBUTYRIN; TRIHEXANOIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; COMPARTMENT MODEL; DILUTION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG HYPERSENSITIVITY; DRUG RETENTION; EVALUATION; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MEAN RESIDENCE TIME; MICROEMULSION; NONHUMAN; PARTICLE SIZE; PRESCRIBED BURNING; RAT; RAT STRAIN; SELF EMULSIFYING MICROEMULSION FORMULATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHEMISTRY, PHARMACEUTICAL; DRUG HYPERSENSITIVITY; EMULSIONS; GUINEA PIGS; MALE; PACLITAXEL; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY;

EID: 33646227652     PISSN: 10797440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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