Leaching of diethylhexyl phthalate from polyvinyl chloride materials into etoposide intravenous solutions

Journal of Oncology Pharmacy Practice

Volumn 11, Issue 4, 2005, Pages 155-157

  De Lemos, Mário L ^a   Hamata, Linda ^a   Vu, Thanh ^a  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

Diethylhexyl phthalate; Drug incompatibility; Etoposide; Polyvinyl chloride

Indexed keywords

ETOPOSIDE; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; POLYVINYLCHLORIDE; SODIUM CHLORIDE;

ARTICLE; CANCER CENTER; CONTINUOUS INFUSION; DRUG CONTAMINATION; DRUG INFUSION; EMBASE; HUMAN; INFORMATION RETRIEVAL; LEACHING; MALIGNANT NEOPLASTIC DISEASE; MEDICAL INFORMATION; MEDICAL LITERATURE; MEDLINE; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; DIETHYLHEXYL PHTHALATE; DRUG CONTAMINATION; DRUG PACKAGING; ETOPOSIDE; INFUSIONS, INTRAVENOUS; PHARMACEUTICAL SOLUTIONS; POLYVINYL CHLORIDE; SOLUBILITY;

EID: 33646190758     PISSN: 10781552     EISSN: None     Source Type: Journal    
DOI: 10.1191/1078155205jp164oa     Document Type: Article

References (20)

1. Demore D, Vigneron A, Perrin A, et al. Leaching of diethylhexyl phthalate from polyvinyl chloride bags into intravenous etoposide solution. J Clin Pharm Ther 2002; 27: 139-42.
2. Bagel-Boithias S, Satou-Miranda V, Bourdeaux D, et al. Leaching of diethylhexyl phthalate from multilayer tubing into infusion solutions. Am J Health Syst Pharm 2005; 62(2): 182-88.
3. Government of Canada. Priority substances list assessment report. Bis(2-ethylhexyl) phthalate. 1994.
4. Pearson SD, Trissel LA. Leaching of diethylhexyl phthalate from polyvinyl chloride containers by selected drugs and formulation components. Am J Hosp Pharm 1993; 50(7): 1405-409.
5. Barthes DM, Rochard EB, Pouliquen IJ, et al. Stability and compatibility of etoposide in 0.9% sodium chloride injection in three containers. Am J Hosp Pharm 1994; 51(21): 2706-709.
6. Bristol Laboratories of Canada. Vepesid product monograph. Bristol-Myers Squibb Canada Inc., March, 2000.
7. Novopharm Limited. Etoposide injection. Novopharm Ltd., 27 January, 1997.
8. Kinda K. Personal communication. Associate, Medical Information and Drug Safety, Bristol-Myers Squibb Canada, 2005.
9. Bagel-Boithias S, Sautou-Miranda V, Bourdeaux D, et al. Leaching of diethylhexyl phthalate from multilayer tubing into etoposide infusion solutions. Am J Health Syst Pharm 2005; 62(2): 182-88.
10. Douchet L. Personal communication. Staff Pharmacist, Cross Cancer Institute, Edmonton, Alberta, 2005.
11. Kagoma S. Personal communication. Pharmacy Manager, Hamilton Regional Cancer Centre, Hamilton, Ont., 2005.
12. The Ottawa Hospital. Parenteral drug therapy manual, 2005.
13. Ng P. Personal communication. Drug Information Pharmacist, Princess Margaret Hospital, Toronto, Ont., 2005.
14. Sims-McCallum R. Personal communication. PharmD Children's Hospital of Michigan, Detroit, 2005.
15. Karpinski J. Personal communication. Clinical Specialist - Drug Information, MD Anderson Cancer Center, Houston, TX, 2005.
16. Leather H. Personal communication. BPharm, BCPS, Clinical Pharmacy Specialist BMT/Leukemia, 2005.
17. Blake D. Personal communication. Lead Pharmacist, North London Cancer Network, 2005.
18. Sautou-Miranda V. Personal communication. Pharmacist, Montpied Hospital Complex, University City: Clermont-Ferrand, France, 2005.
19. Demoré B. Personal communication. Pharmacie Brabois Adultes - Centre Hospitalier Universitaire de Nancy, 30 April, 2005.
20. Lees J. Personal communication. PharmD, Royal Adelaide Hospital, Australia, 2005.