The Chemotaxis Response Regulator CheY Can Catalyze its Own Acetylation

Journal of Molecular Biology

Volumn 359, Issue 2, 2006, Pages 251-265

  Barak, Rina ^a   Yan, Jianshe ^a   Shainskaya, Alla ^a   Eisenbach, Michael ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

acetylation; autoacetylation; bacterial chemotaxis; chemotaxis; CheY

Indexed keywords

ACETYL COENZYME A SYNTHETASE; BACTERIAL PROTEIN; CARBON 14; CHEA KINASE; PHOSPHATASE; PHOSPHATE; PROTEIN CHEY; PROTEIN CHEZ; UNCLASSIFIED DRUG;

ACETYLATION; AMINO ACID SEQUENCE; ARTICLE; BACTERIAL FLAGELLUM; CATALYSIS; CHEMOTAXIS; CONTROLLED STUDY; ESCHERICHIA COLI; GENE DELETION; GENE ISOLATION; GENE MUTATION; IN VIVO STUDY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STRUCTURE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 33646187138     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.03.033     Document Type: Article

References (46)

1. Eisenbach M. Chemotaxis (2004), Imperial College Press, London
2. Barak R., Welch M., Yanovsky A., Oosawa K., and Eisenbach M. Acetyladenylate or its derivative acetylates the chemotaxis protein CheY in vitro and increases its activity at the flagellar switch. Biochemistry 31 (1992) 10099-10107
3. Barak R., Prasad K., Shainskaya A., Wolfe A.J., and Eisenbach M. Acetylation of the chemotaxis response regulator CheY by acetyl-CoA synthetase from Escherichia coli. J. Mol. Biol. 342 (2004) 383-401
4. Barak R., and Eisenbach M. Co-regulation of acetylation and phosphorylation of CheY, a response regulator in chemotaxis of Escherichia coli. J. Mol. Biol. 342 (2004) 375-381
5. Barak R., and Eisenbach M. Acetylation of the response regulator, CheY, is involved in bacterial chemotaxis. Mol. Microbiol. 40 (2001) 731-743
6. Sterner D.E., and Berger S.L. Acetylation of histones and transcription-related factors. Microbiol. Mol. Biol. Rev. 64 (2000) 435-459
7. Herrera J.E., Bergel M., Yang X.J., Nakatani Y., and Bustin M. The histone acetyltransferase activity of human GCN5 and PCAF is stabilized by coenzymes. J. Biol. Chem. 272 (1997) 27253-27258
8. Creaven M., Hans F., Mutskov V., Col E., Caron C., Dimitrov S., and Khochbin S. Control of the histone-acetyltransferase activity of Tip60 by the HIV-1 transactivator protein, Tat. Biochemistry 38 (1999) 8826-8830
9. Allen S.C., and Hebbes T.R. Myb induced myeloid protein 1 (Mim-1) is an acetyltransferase. FEBS Letters 534 (2003) 119-124
10. Santos-Rosa H., Valls E., Kouzarides T., and Martinez-Balbas M. Mechanisms of P/CAF auto-acetylation. Nucl. Acids Res. 31 (2003) 4285-4292
11. Thompson P.R., Wang D., Wang L., Fulco M., Pediconi N., Zhang D., et al. Regulation of the p300 HAT domain via a novel activation loop. Nature Struct. Mol. Biol. 11 (2004) 308-315
12. Choi C.H., Hiromura M., and Usheva A. Transcription factor IIB acetylates itself to regulate transcription. Nature 424 (2003) 965-969
13. Choi C.H., Burton Z.F., and Usheva A. Auto-acetylation of transcription factors as a control mechanism in gene expression. Cell Cycle 3 (2004) 114-115
14. Borchers C., Parker C.E., Deterding L.J., and Tomer K.B. Preliminary comparison of precursor scans and liquid chromatography-tandem mass spectrometry on a hybrid quadrupole time-of-flight mass spectrometer. J. Chromatog. sect. A 854 (1999) 119-130
15. Kim J.Y., Kim K.W., Kwon H.J., Lee D.W., and Yoo J.S. Probing lysine acetylation with a modification-specific marker ion using high-performance liquid chromatography/electrospray-mass spectrometry with collision-induced dissociation. Anal. Chem. 74 (2002) 5443-5449
16. Vallari D.S., and Jackowski S. Biosynthesis and degradation both contribute to the regulation of Coenzyme A content in Escherichia coli. J. Bacteriol. 170 (1988) 3961-3966
17. Silverman M., and Simon M. Flagellar rotation and the mechanism of bacterial motility. Nature 249 (1974) 73-74
18. Montrone M., Eisenbach M., Oesterhelt D., and Marwan W. Regulation of switching frequency and bias of the bacterial flagellar motor by CheY and fumarate. J. Bacteriol. 180 (1998) 3375-3380
19. Prasad K., Caplan S.R., and Eisenbach M. Fumarate modulates bacterial flagellar rotation by lowering the free energy difference between the clockwise and counterclockwise states of the motor. J. Mol. Biol. 280 (1998) 821-828
20. Barak R., and Eisenbach M. Fumarate or a fumarate metabolite restores switching ability to rotating flagella of bacterial envelopes. J. Bacteriol. 174 (1992) 643-645
21. Barak R., Giebel I., and Eisenbach M. The specificity of fumarate as a switching factor of the bacterial flagellar motor. Mol. Microbiol. 19 (1996) 139-144
22. Tso W.-W., and Adler J. Negative chemotaxis in Escherichia coli. J. Bacteriol. 118 (1974) 560-576
23. Shioi J.-I., Galloway R.J., Niwano M., Chinnock R.E., and Taylor B.L. Requirement of ATP in bacterial chemotaxis. J. Biol. Chem. 257 (1982) 7969-7975
24. Adler J. Chemotaxis in bacteria. Harvey Lect. 72 (1978) 195-230
25. Springer M.S., Goy M.F., and Adler J. Protein methylation in behavioral control mechanisms and in signal transduction. Nature 280 (1979) 279-284
26. Yan, J. (2005). CheY acetylation in bacterial chemotaxis: function and regulation. PhD thesis, Weizmann Institute of Science, Rehovot, Israel.
27. Khan S., and Macnab R.M. The steady-state counterclockwise/clockwise ratio of bacterial flagellar motors is regulated by proton-motive force. J. Mol. Biol. 138 (1980) 563-597
28. Khan S., and Macnab R.M. Proton chemical potential, proton electrical potential and bacterial motility. J. Mol. Biol. 138 (1980) 599-614
29. Dailey F.E., and Berg H.C. Change in direction of flagellar rotation in Escherichia coli mediated by acetate kinase. J. Bacteriol. 175 (1993) 3236-3239
30. Wolfe A.J., Conley M.P., and Berg H.C. Acetyladenylate plays a role in controlling the direction of flagellar rotation. Proc. Natl Acad. Sci. USA 85 (1988) 6711-6715
31. Kumari S., Tishel R., Eisenbach M., and Wolfe A.J. Cloning, characterization, and functional expression of acs, the gene which encodes acetyl-coenzyme A synthetase in Escherichia coli. J. Bacteriol. 177 (1995) 2878-2886
32. Barak R., Abouhamad W.N., and Eisenbach M. Both acetate kinase and acetyl Coenzyme A synthetase are involved in acetate-stimulated change in the direction of flagellar rotation in Escherichia coli. J. Bacteriol. 180 (1998) 985-988
33. Ramakrishnan R., Schuster M., and Bourret R.B. Acetylation at Lys-92 enhances signaling by the chemotaxis response regulator protein CheY. Proc. Natl Acad. Sci. USA 95 (1998) 4918-4923
34. Lukat G.S., McCleary W.R., Stock A.M., and Stock J.B. Phosphorylation of bacterial response regulator proteins by low molecular weight phospho-donors. Proc. Natl Acad. Sci. USA 89 (1992) 718-722
35. Mayover T.L., Halkides C.J., and Stewart R.C. Kinetic characterization of CheY phosphorylation reactions: comparison of P-CheA and small-molecule phosphodonors. Biochemistry 38 (1999) 2259-2271
36. Wolfe A.J. The acetate switch. Microbiol. Mol. Biol. Rev. 69 (2005) 12-50
37. Kumari S., Beatty C.M., Browning D.F., Busby S.J.W., Simel E.J., Hovel-Miner G., and Wolfe A.J. Regulation of acetyl coenzyme A synthetase in Escherichia coli. J. Bacteriol. 182 (2000) 4173-4179
38. Vogel H.J., and Bonner D.M. Acetylornithinase of Escherichia coli, partial purification and some properties. J. Biol. Chem. 218 (1956) 97-106
39. Blat Y., and Eisenbach M. Phosphorylation-dependent binding of the chemotaxis signal molecule CheY to its phosphatase, CheZ. Biochemistry 33 (1994) 902-906
40. Ravid S., and Eisenbach M. Correlation between bacteriophage chi adsorption and mode of flagellar rotation of Escherichia coli chemotaxis mutants. J. Bacteriol. 154 (1983) 604-611
41. Berg H.C., and Block S.M. A miniature flow cell designed for rapid exchange of media under high-power microscope objectives. J. Gen. Microbiol. 130 (1984) 2915-2920
42. Stanley P.E., and Williams S.G. Use of liquid scintillation spectrometer for determining adenosine triphosphate by luciferase enzyme. Anal. Biochem. 29 (1969) 381-392
43. 2+-ATPase reveal novel features of its pumping mechanism. J. Biol. Chem. 279 (2004) 43971-43981
44. Shevchenko A., Wilm M., Vorm O., and Mann M. Anal. Chem. 68 (1966) 850-858
45. Wilm M., Neubauer G., and Mann M. Parent ion scans of unseparated peptide mixtures. Anal. Chem. 68 (1996) 527-533
46. Parkinson J.S. Complementation analysis and deletion mapping of Escherichia coli mutants defective in chemotaxis. J. Bacteriol. 135 (1978) 45-53