Role of whole body positron emission tomography/computed tomography scan with 18F-fluorodeoxyglucose in patients with biopsy proven tumor metastases from unknown primary site

Quarterly Journal of Nuclear Medicine and Molecular Imaging

Volumn 50, Issue 1, 2006, Pages 15-22

  Pelosi, E ^a   Pennone, M ^a   Deandreis, D ^a   Douroukas, A ^b   Mancini, M ^b   Bisi, Gianni ^a,c  

^a MOLINETTE HOSPITAL   (Italy)

^b PET Center IRMET SpA   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

Computed tomography; Emission computed; Etiology; Fluorodeoxyglucose; Metastases; Neoplasms; Tomography; Tumor staging

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ADULT; AGED; ARTICLE; CANCER LOCALIZATION; CANCER STAGING; COLON CANCER; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; FEMALE; FOLLOW UP; HUMAN; IMAGE ANALYSIS; LABORATORY TEST; LUNG CANCER; LYMPH NODE BIOPSY; MAJOR CLINICAL STUDY; MALE; METASTASIS; METASTASIS POTENTIAL; NASOPHARYNX CANCER; OROPHARYNX CANCER; PANCREAS CANCER; PHYSICAL EXAMINATION; TUMOR BIOPSY; UTERUS CANCER;

ADULT; AGED; BIOPSY; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; ITALY; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASMS, UNKNOWN PRIMARY; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SUBTRACTION TECHNIQUE; TOMOGRAPHY, X-RAY COMPUTED; WHOLE BODY IMAGING;

EID: 33646186320     PISSN: 18244785     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Chorost MI, Lee MC, Yeoh CB, Molina M, Ghosh BC. Unknown primary. J Surg Oncol 2004;87:191-203.
2. Levi F, Te VC, Erler G, Randimbison L, La Vecchia C. Epidemiology of unknown primary tumours. Eur J Cancer 2002;38:1810-2.
3. Pavlidis N, Briasoulis E, Hainsworth J, Greco FA. Diagnostic and therapeutic management of cancer of unknown primary. Eur J Cancer 2003;39:1990-2005.
4. Abbruzzese JL, Abbruzzese MC, Lenzi R, Hess KR, Raber MN. Analysis of a diagnostic strategy for patients with suspected tumors of unknown origin. J Clin Oncol 1995;13:2094-103.
5. Le Chevalier T, Cvitkovic E, Caille P, Harvey J, Contesso G, Spielmann M et al. Early metastatic cancer of unknown primary origin at presentation. A clinical study of 302 consecutive autopsied patients. Arch Intern Med 1988;148:2035-9.
6. Braams JW, Pruim J, Kole AC, Nikkels PG, Vaalburg W, Vermey A et al. Detection of unknown primary head and neck tumors by positron emission tomography. Int J Oral Maxillofac Surg 1997;26: 112-5.
7. AAssar OS, Fischbein NJ, Caputo GR, Kaplan MJ, Price DC, Singer MI et al. Metastatic head and neck cancer: role and usefulness of FDG PET in locating occult primary tumors. Radiology 1999;210: 177-81.
8. Hanasono MM, Kunda LD, Segall GM, Ku GH, Terris DJ. Uses and limitations of FDG positron emission tomography in patients with head and neck cancer. Laryngoscope 1999;109:880-5.
9. Kole AC, Nieweg OE, Pruim J, Hoekstra HJ, Koops HS, Roodenburg JL et al. Detection of unknown occult primary tumors using positron emission tomography. Cancer 1998;82:1160-6.
10. 18F-FDG whole body positron emission tomography (PET) in patients with unknown primary tumours (UPT). Eur J Cancer 1999; 35:1076-82.
11. Bohuslavizki KH, Klutmann S, Kroger S, Sonnemann U, Buchert R, Werner JA et al. FDG PET detection of unknown primary tumors. J Nucl Med 2000;41:816-22.
12. Lonneux M, Reffad A. Metastases from unknown primary tumor. PET-FDG as initial diagnostic procedure? Clin Positron Imaging 2000;3:137-41.
13. Reske SN, Kotzerke J. FDG-PET for clinical use. Results of the 3rd German Interdisciplinary Consensus Conference, "Onko-PET III", 21 July and 19 September 2000. Eur J Nucl Med 2001;28:1707-23.
14. Delgado-Bolton RC, Fernandez-Perez C, Gonzalez-Mate A, Carreras JL. Meta-Analysis of the performance of 18F-FDG PET in primary tumor detection in unknown primary tumors. J Nucl Med 2003;44:1301-14.
15. Beyer T, Townsend DW, Brun T, Kinahan PE, Charron M, Roddy R et al. A combined PET/CT scanner for clinical oncology. J Nucl Med 2000;41:1369-79.
16. Kluetz PG, Meltzer CC, Villemagne VL, Kinahan PE, Chander S, Martinelli MA et al. Combined PET/TC imaging in oncology. Impact on patient management. Clin Positron Imaging 2000;3:223-30.
17. Townsend DW. A combined PET/CT scanner: the choices. J Nucl Med 2001;42:533-4.
18. Hany TF, Steinert HC, Goerres GW, Buck A, von Schulthess GK. PET diagnostic accuracy: improvement with in-line PET-CT system: initial results. Radiology 2002;225:575-81.
19. Lardinois D, Weder W, Hany TF, Kamel EM, Korom S, Seifert B et al. Staging of non-small-cell lung cancer with integrated positron-emission tomography and computed tomography. N Engl J Med 2003;348:2500-7.
20. Bar-Shalom R, Yefremov N, Guralnik L, Gaitini D, Frenkel A, Kuten A et al. Clinical performance of PET/CT in evaluation of cancer: additional value for diagnostic imaging and patient management. J Nucl Med 2003;44:1200-9.
21. Pelosi E, Messa C, Sironi S, Picchio M, Landoni C, Bettinardi V et al. Value of integrated PET/CT for lesion localisation in cancer patients: a comparative study. Eur J Nucl Med Mol Imaging 2004;31:932-9.
22. Gutzeit A, Antoch G, Kuhl H, Egelhof T, Fischer M, Hauth E et al. Unknown primary tumors: detection with dual-modality PET/CT: initial experience. Radiology 2005;234:227-34.
23. Nanni C, Rubello D, Castellucci P, Farsad M, Franchi R, Toso S et al. Role of 18F-FDG PET-CT imaging for the detection of an unknown primary tumour: preliminary results in 21 patients. Eur J Nucl Med Mol Imaging 2005;32:589-92.
24. Lenzi R, Hess KR, Abbruzzese MC, Raber MN, Ordonez NG, Abbruzzese JL. Poorly differentiated carcinoma and poorly differentiated adenocarcinoma of unknown origin: favorable subsets of patients with unknown-primary carcinoma? J Clin Oncol 1997;15:2056-66.
25. Rusthoven KE, Koshy M, Paulino AC. The role of fluorodeoxyglucose positron emission tomography in cervical lymph node metastases from an unknown primary tumor. Cancer 2004;101:2641-9.
26. Joshi U, van der Hoeven JJ, Comans EF, Herder GJ, Teule GJ, Hoekstra OS. In search of an unknown primary tumour presenting with extracervical metastases: the diagnostic performance of FDG-PET. Br J Radiol 2004;77:1000-6.
27. Ghosh L, Dahut W, Kakar S, Posadas EM, Torres CG, Cancel-Santiago R et al. Management of patients with metastatic cancer of unknown primary. Curr Probl Surg 2005;42:12-66.
28. Naresh KN. Do metastatic tumours from an unknown primary reflect angiogenic incompetence of the tumour at the primary site? A hypothesis. Med Hypotheses 2002;59:357-60.