-
1
-
-
0347364629
-
Gi protein activation in intact cells involves subunit rearrangement rather than dissociation
-
Bunemann, M., M. Frank, and M. J. Lohse. 2003. Gi protein activation in intact cells involves subunit rearrangement rather than dissociation. Proc. Natl. Acad. Sci. USA. 100:16077-16082.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 16077-16082
-
-
Bunemann, M.1
Frank, M.2
Lohse, M.J.3
-
2
-
-
0032557490
-
Molecular basis for interactions of G protein betagamma subunits with effectors
-
Ford, C. E., N. P. Skiba, H. Bae, Y. Daaka, E. Reuveny, L. R. Shekter, R. Rosal, G. Weng, C. S. Yang, R. Iyengar, R. J. Miller, L. Y. Jan, R. J. Lefkowitz, and H. E. Hamm. 1998. Molecular basis for interactions of G protein betagamma subunits with effectors. Science. 280:1271-1274.
-
(1998)
Science
, vol.280
, pp. 1271-1274
-
-
Ford, C.E.1
Skiba, N.P.2
Bae, H.3
Daaka, Y.4
Reuveny, E.5
Shekter, L.R.6
Rosal, R.7
Weng, G.8
Yang, C.S.9
Iyengar, R.10
Miller, R.J.11
Jan, L.Y.12
Lefkowitz, R.J.13
Hamm, H.E.14
-
3
-
-
0033605365
-
Resolution of a signal transfer region from a general binding domain in Gbeta for stimulation of phospholipase C-beta2
-
Buck, E., J. Li, Y. Chen, G. Weng, S. Scarlata, and R. Iyengar. 1999. Resolution of a signal transfer region from a general binding domain in Gbeta for stimulation of phospholipase C-beta2. Science. 283:1332-1335.
-
(1999)
Science
, vol.283
, pp. 1332-1335
-
-
Buck, E.1
Li, J.2
Chen, Y.3
Weng, G.4
Scarlata, S.5
Iyengar, R.6
-
5
-
-
0029743416
-
Localization of the effector-specifying regions of Gi2alpha and Gqalpha
-
Medina, R., G. Grishina, E. G. Meloni, T. R. Muth, and C. H. Berlot. 1996. Localization of the effector-specifying regions of Gi2alpha and Gqalpha. J. Biol. Chem. 271:24720-24727.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24720-24727
-
-
Medina, R.1
Grishina, G.2
Meloni, E.G.3
Muth, T.R.4
Berlot, C.H.5
-
6
-
-
0035865394
-
Evidence that a protein-protein interaction 'hot spot' on heterotrimeric G protein betagamma subunits is used for recognition of a subclass of effectors
-
Scott, J. K., S.-F. Huang, B. P. Gangadhar, G. M. Samoriski, P. Clapp, R. A. Gross, R. Taussig, and A. V. Smrcka. 2001. Evidence that a protein-protein interaction 'hot spot' on heterotrimeric G protein betagamma subunits is used for recognition of a subclass of effectors. EMBO J. 20:767-776.
-
(2001)
EMBO J.
, vol.20
, pp. 767-776
-
-
Scott, J.K.1
Huang, S.-F.2
Gangadhar, B.P.3
Samoriski, G.M.4
Clapp, P.5
Gross, R.A.6
Taussig, R.7
Smrcka, A.V.8
-
7
-
-
0030034646
-
Crystal structure of a G-protein beta gamma dimer at 2.1 Å resolution
-
Sondek, J., A. Bohm, D. G. Lambright, H. E. Hamm, and P. B. Sigler. 1996. Crystal structure of a G-protein beta gamma dimer at 2.1 Å resolution. Nature. 379:369-374.
-
(1996)
Nature
, vol.379
, pp. 369-374
-
-
Sondek, J.1
Bohm, A.2
Lambright, D.G.3
Hamm, H.E.4
Sigler, P.B.5
-
8
-
-
0029593456
-
The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2
-
Wall, M. A., D. E. Coleman, E. Lee, J. A. Iniguez-Lluhi, B. A. Posner, A. G. Gilman, and S. R. Sprang. 1995. The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2. Cell. 83:1047-1058.
-
(1995)
Cell
, vol.83
, pp. 1047-1058
-
-
Wall, M.A.1
Coleman, D.E.2
Lee, E.3
Iniguez-Lluhi, J.A.4
Posner, B.A.5
Gilman, A.G.6
Sprang, S.R.7
-
9
-
-
0030297912
-
Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin
-
Gaudet, R., A. Bohm, and P. B. Sigler. 1996. Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin. Cell. 87:577-588.
-
(1996)
Cell
, vol.87
, pp. 577-588
-
-
Gaudet, R.1
Bohm, A.2
Sigler, P.B.3
-
10
-
-
0037799206
-
Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gbetagamma
-
Lodowski, D. T., J. A. Pitcher, W. D. Capel, R. J. Lefkowitz, and J. J. G. Tesmer. 2003. Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma. Science. 300:1256-1262.
-
(2003)
Science
, vol.300
, pp. 1256-1262
-
-
Lodowski, D.T.1
Pitcher, J.A.2
Capel, W.D.3
Lefkowitz, R.J.4
Tesmer, J.J.G.5
-
13
-
-
0028322077
-
Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits
-
Reuveny, E., P. A. Slesinger, J. Inglese, J. M. Morales, J. A. Iniguez-Lluhi, R. J. Lefkowitz, H. R. Bourne, Y. N. Jan, and L. Y. Jan. 1994. Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits. Nature. 370:143-146.
-
(1994)
Nature
, vol.370
, pp. 143-146
-
-
Reuveny, E.1
Slesinger, P.A.2
Inglese, J.3
Morales, J.M.4
Iniguez-Lluhi, J.A.5
Lefkowitz, R.J.6
Bourne, H.R.7
Jan, Y.N.8
Jan, L.Y.9
-
14
-
-
0032610005
-
G protein gated potassium channels
-
Sui, J. L., K. W. Chan, M. N. Langan, M. Vivaudou, and D. E. Logothetis. 1999. G protein gated potassium channels. Adv. Second Messenger Phosphoprotein Res. 33:179-201.
-
(1999)
Adv. Second Messenger Phosphoprotein Res.
, vol.33
, pp. 179-201
-
-
Sui, J.L.1
Chan, K.W.2
Langan, M.N.3
Vivaudou, M.4
Logothetis, D.E.5
-
15
-
-
0027219695
-
Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel
-
Kubo, Y., E. Reuveny, P. A. Slesinger, Y. N. Jan, and L. Y. Jan. 1993. Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel. Nature. 364:802-806.
-
(1993)
Nature
, vol.364
, pp. 802-806
-
-
Kubo, Y.1
Reuveny, E.2
Slesinger, P.A.3
Jan, Y.N.4
Jan, L.Y.5
-
18
-
-
0032415101
-
Protein regulation of potassium ion channels
-
Yamada, M., A. Inanobe, and Y. G. Kurachi. 1998. Protein regulation of potassium ion channels. Pharmacol. Rev. 50:723-757.
-
(1998)
Pharmacol. Rev.
, vol.50
, pp. 723-757
-
-
Yamada, M.1
Inanobe, A.2
Kurachi, Y.G.3
-
21
-
-
0037183977
-
Distinct sites on G protein beta gamma subunits regulate different effector functions
-
Mirshahi, T., V. Mittal, H. Zhang, M. E. Linder, and D. E. Logothetis. 2002. Distinct sites on G protein beta gamma subunits regulate different effector functions. J. Biol. Chem. 277:36345-36350.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36345-36350
-
-
Mirshahi, T.1
Mittal, V.2
Zhang, H.3
Linder, M.E.4
Logothetis, D.E.5
-
22
-
-
0028854127
-
Dominant solvation effects from primary shell of hydration: Approximation for molecular dynamics simulations
-
Beglov, D., and B. Roux. 1995. Dominant solvation effects from primary shell of hydration: approximation for molecular dynamics simulations. Biopolymers. 35:171-178.
-
(1995)
Biopolymers
, vol.35
, pp. 171-178
-
-
Beglov, D.1
Roux, B.2
-
23
-
-
84986512474
-
CHARMM: A program for macromolecular energy, minimization, and dynamics calculations
-
Brooks, B. R., R. Bruccoleri, B. Olafson, D. States, S. Swaminathan, and M. Karplus. 1983. CHARMM: a program for macromolecular energy, minimization, and dynamics calculations. J. Comput. Chem. 4:187-217.
-
(1983)
J. Comput. Chem.
, vol.4
, pp. 187-217
-
-
Brooks, B.R.1
Bruccoleri, R.2
Olafson, B.3
States, D.4
Swaminathan, S.5
Karplus, M.6
-
24
-
-
0028304962
-
Satisfying hydrogen-bonding potential in proteins
-
McDonald, I. K., and J. M. Thornton. 1994. Satisfying hydrogen-bonding potential in proteins. J. Mol. Biol. 238:777-793.
-
(1994)
J. Mol. Biol.
, vol.238
, pp. 777-793
-
-
McDonald, I.K.1
Thornton, J.M.2
-
26
-
-
0001664516
-
+ activation of the muscarinic K+ channel by a G-protein-independent mechanism
-
+ activation of the muscarinic K+ channel by a G-protein-independent mechanism. J. Gen. Physiol. 108:381-391.
-
(1996)
J. Gen. Physiol.
, vol.108
, pp. 381-391
-
-
Sui, J.L.1
Chan, K.W.2
Logothetis, D.E.3
-
27
-
-
0346118921
-
Critical determinants of the G protein gamma subunits in the Gbetagamma stimulation of G protein-activated inwardly rectifying potassium (GIRK) channel activity
-
Peng, L., T. Mirshahi, H. Zhang, J. P. Hirsch, and D. E. Logothetis. 2003. Critical determinants of the G protein gamma subunits in the Gbetagamma stimulation of G protein-activated inwardly rectifying potassium (GIRK) channel activity. J. Biol. Chem. 278:50203-50211.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50203-50211
-
-
Peng, L.1
Mirshahi, T.2
Zhang, H.3
Hirsch, J.P.4
Logothetis, D.E.5
-
28
-
-
0032530652
-
Structural basis of activity and subunit recognition in G protein heterotrimers
-
Wall, M. A., B. A. Posner, and S. R. Sprang. 1998. Structural basis of activity and subunit recognition in G protein heterotrimers. Structure. 6:1169-1183.
-
(1998)
Structure
, vol.6
, pp. 1169-1183
-
-
Wall, M.A.1
Posner, B.A.2
Sprang, S.R.3
-
29
-
-
0028031159
-
Direct interaction of the alpha and gamma subunits of the G proteins. Purification and analysis by limited proteolysis
-
Rahmatullah, M., and J. D. Robishaw. 1994. Direct interaction of the alpha and gamma subunits of the G proteins. Purification and analysis by limited proteolysis. J. Biol. Chem. 269:3574-3580.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 3574-3580
-
-
Rahmatullah, M.1
Robishaw, J.D.2
-
30
-
-
0034662983
-
Activation and inhibition of G protein-coupled inwardly rectifying potassium (Kir3) channels by G protein beta gamma subunits
-
Lei, Q., M. B. Jones, E. M. Talley, A. D. Schrier, W. E. McIntire, J. C. Garrison, and D. A. Bayliss. 2000. Activation and inhibition of G protein-coupled inwardly rectifying potassium (Kir3) channels by G protein beta gamma subunits. Proc. Natl. Acad. Sci. USA. 97:9771-9776.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 9771-9776
-
-
Lei, Q.1
Jones, M.B.2
Talley, E.M.3
Schrier, A.D.4
McIntire, W.E.5
Garrison, J.C.6
Bayliss, D.A.7
-
31
-
-
0031436257
-
Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants
-
Vivaudou, M., K. W. Chan, J. L. Sui, L. Y. Jan, E. Reuveny, and D. E. Logothetis. 1997. Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants. J. Biol. Chem. 272:31553-31560.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 31553-31560
-
-
Vivaudou, M.1
Chan, K.W.2
Sui, J.L.3
Jan, L.Y.4
Reuveny, E.5
Logothetis, D.E.6
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