Regulation of ERK MAPK in oridonin-enhanced phagocytosis of apoptotic bodies in human macrophage-like U937 cells

Chinese Pharmacological Bulletin

Volumn 22, Issue 1, 2006, Pages 110-113

  Liu, Yan Qiu ^a   You, Song ^a   Tashiro, Shin Ichi ^b   Onodera, Satoshi ^b   Ikejima, Takashi ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

ERK; Oridonin; Phagocytosis; U937 cell

Indexed keywords

GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE; ORIDONIN; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; STAUROSPORINE;

APOPTOSIS; ARTICLE; CELL STRAIN U937; CONTROLLED STUDY; HUMAN; HUMAN CELL; MACROPHAGE; PHAGOCYTOSIS; PHOSPHORYLATION; WESTERN BLOTTING;

EID: 33646171293     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Liu VQ, You S, Zhang CL et al. Oridonin enhances phagocytosis of UV-irradiated apoptotic U937 cells[J]. Biol Pharm Bull, 2005, 28(3):461-7.
2. Suzuki K, Hino M, Kutsuna H et al. Selective activation of p38 Mitogen-ativated protein kinase in human neutrophils stimulated by IL-1β[J]. J Immunol, 2001, 167(10):5940-7.
3. Smith JA. Neutrophils, host defense, and inflammation:a double-edged sword[J]. J Leukocyte Biol, 1994, 56(6):672-86.
4. Procyk KJ, Kovarik P, Gabain A et al. Salmonella typhimurium and lipopolysaccharide stimulate extracellularly regulated kinase activation in macrophages by a mechanism involving phosphatidylinositol 3-kinase and phospholipase D as novel intermediates[J]. Infection Immunity, 1999, 67(3):1011-7.
5. Savill J, Fadok V. Corpse clearance defines the meaning of cell death[J]. Nature, 2000, 407(6805):784-8.
6. Osawa K, Yasuda H, Maruyama T et al. Antibacterial trichorabdal diterpenes from Rabdosia Trichocarpa[J]. Phytochemistry, 1994, 36(5):1287-91.
7. Zhang CL, Wu LJ, Zuo HJ et al. Oridonin induces a caspase-independent but mitochondria- and MAPK-dependent cell death in the murine fibrosarcoma cell line L929[J]. Biol Pharm Bull, 2004, 27(10):1527-31.
8. Liu MK, Herrera-Velit P, Brownsey RW et al. CD14-dependent activation of protein kinase C and mitogen-activated protein kinases (p42 and p44) in human monocytes treated with bacterial lipopolysaccharide[J]. J Immunol, 1994,153(6):2642-52.
9. Greenberg S, Chang P, Silverstein SC. Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages[J]. J Exp Med, 1993, 177(2):529-34.
10. Hu B, Punturieri A, Todt J et al. Recognition and phagocytosis of apoptotic T cells by resident murine tissue macrophages require multiple signal transduction events[J]. J Leukoc Biol, 2002, 71 (5):881-9.
11. Downey GP, Butler JR, Tapper H et al. Importance of MEK in neutrophil rnicrobicidal responsiveness[J]. J Immunol, 1998, 160 (1):434-43.